YNK1 |
YKL067W |
Nucleoside diphosphate kinase |
physical |
4 |
4 |
4 |
Two-hybrid, Biochemical Activity, PCA, Co-crystal Structure |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP95 |
YLR347C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Two-hybrid |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
1 |
1 |
1 |
Two-hybrid |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMD1 |
YBR109C |
Calmodulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM25 |
YJL201W |
Endocytic site protein required for stress-induced cell elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO4 |
YBR249C |
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPC54 |
YOR177C |
Component of the meiotic outer plaque |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJU2 |
YKL095W |
Essential protein required for pre-mRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSL1 |
YML100W |
Large subunit of trehalose 6-phosphate synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEN15 |
YMR059W |
Subunit of the tRNA splicing endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PPE1 |
YHR075C |
Protein with carboxyl methyl esterase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALD5 |
YER073W |
Mitochondrial aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Negative Genetic |
BNA5 |
YLR231C |
Kynureninase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
IME1 |
YJR094C |
Master regulator of meiosis that is active only during meiotic events |
genetic |
1 |
1 |
1 |
Negative Genetic |
AKR2 |
YOR034C |
Ankyrin repeat-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YSA1 |
YBR111C |
Nudix hydrolase family member with ADP-ribose pyrophosphatase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR105W |
YOR105W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR111W |
YOR111W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS24B |
YIL069C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCD1 |
YHR144C |
Deoxycytidine monophosphate (dCMP) deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOM40 |
YMR203W |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPR1 |
YLR014C |
Zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSY2 |
YLR258W |
Glycogen synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMA17 |
YIL029C |
Protein involved in targeting mitochondrial membrane protein precursor |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDR5 |
YOR153W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNK1 |
YKL171W |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FUS1 |
YCL027W |
Membrane protein localized to the shmoo tip |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRR1 |
YLR213C |
Putative glycoside hydrolase of the spore wall envelope |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADI1 |
YMR009W |
Acireductone dioxygenease involved in methionine salvage pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ3 |
YOL096C |
O-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BDH1 |
YAL060W |
NAD-dependent (R,R)-butanediol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHA1 |
YCL064C |
Catabolic L-serine (L-threonine) deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRE3 |
YHR104W |
Aldose reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IMO32 |
YGR031W |
Conserved mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATF2 |
YGR177C |
Alcohol acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
OSM1 |
YJR051W |
Fumarate reductase, catalyzes the reduction of fumarate to succinate |
genetic |
1 |
1 |
1 |
Positive Genetic |
PSA1 |
YDL055C |
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22B |
YLR367W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENT4 |
YLL038C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
GUD1 |
YDL238C |
Guanine deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
TMH11 |
YJR085C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUT1 |
YGL162W |
Zn(II)2Cys6 family transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
TMA17 |
YDL110C |
Regulatory gamma subunit of fatty acid synthase (FAS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
1 |
1 |
1 |
Positive Genetic |
MDL2 |
YPL270W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
QDR1 |
YIL120W |
Multidrug transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAS4 |
YOL132W |
1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
YLL058W |
YLL058W |
Putative protein of unknown function with similarity to Str2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTM1 |
YHR109W |
Cytochrome c lysine methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDT1 |
YGL224C |
Pyrimidine nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBX3 |
YDL091C |
Clathrin-coated vesicle component, regulator of endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR029W |
YAR029W |
Member of DUP240 gene family but contains no transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR287C |
YLR287C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR338C |
YDR338C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER078W-A |
YER078W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR326W |
YLR326W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |