Standard name Systematic name Name description Description
YPP1 YGR198W Cargo-transport protein involved in endocytosis Cargo-transport protein involved in endocytosis; interacts with phosphatidylinositol-4-kinase Stt4p; is required, along with Efr3p, for the assembly and recruitment of multiple copies of the kinase into phosphoinositide kinase (PIK) patches at the plasma membrane; positively regulates Stt4p; GFP-fusion protein localizes to the cytoplasm; YGR198W is an essential gene
Visualize the interactome of YPP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.108 0.082 NaN
Cell Periphery 0.247 0.261 0.325
Cort. Patches 0.258 0.232 0.250
Cytoplasm 0.516 0.605 0.625
ER 0.054 NaN NaN
Mito 0.075 NaN NaN
SpindlePole NaN NaN 0.050

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
YPP1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
STT4 YLR305C Phosphatidylinositol-4-kinase physical 6 4 5 Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Negative Genetic
EFR3 YMR212C Protein required for Stt4-containing PI kinase complex localization physical 3 2 3 PCA, Reconstituted Complex, Reconstituted Complex
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 2 1 2 Dosage Rescue, Dosage Rescue
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
ATG15 YCR068W Phospholipase genetic 2 2 1 Positive Genetic, Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED6 YHR058C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ADA2 YDR448W Transcription coactivator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein physical 1 1 1 Affinity Capture-MS
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Synthetic Growth Defect
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases genetic 1 1 1 Phenotypic Enhancement
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Negative Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
UTP6 YDR449C Nucleolar protein physical 1 1 1 Affinity Capture-MS
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Phenotypic Enhancement
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
PEP3 YLR148W Component of CORVET membrane tethering complex genetic 1 1 1 Phenotypic Enhancement
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
PTC3 YBL056W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
ROX3 YBL093C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-MS
CSI1 YMR025W Subunit of the Cop9 signalosome genetic 1 1 1 Negative Genetic
PIL1 YGR086C Eisosome core component genetic 1 1 1 Phenotypic Enhancement
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Phenotypic Enhancement
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles genetic 1 1 1 Negative Genetic
PEP5 YMR231W Histone E3 ligase, component of CORVET membrane tethering complex genetic 1 1 1 Phenotypic Enhancement
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) genetic 1 1 1 Negative Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Phenotypic Enhancement
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Phenotypic Enhancement
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Negative Genetic
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Negative Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Synthetic Lethality
INM1 YHR046C Inositol monophosphatase genetic 1 1 1 Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Positive Genetic
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Negative Genetic
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Positive Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
SNF8 YPL002C Component of the ESCRT-II complex genetic 1 1 1 Phenotypic Enhancement
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 1 1 1 Phenotypic Enhancement
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 1 1 1 Negative Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Phenotypic Enhancement
RPS1A YLR441C Ribosomal protein of the small (40S) subunit genetic 1 1 1 Negative Genetic
RPS1B YML063W Ribosomal protein of the small (40S) subunit genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Synthetic Lethality
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Synthetic Growth Defect
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 1 1 1 Synthetic Lethality
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
SNC1 YAL030W Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Phenotypic Enhancement
TRX1 YLR043C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Phenotypic Enhancement
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Phenotypic Enhancement
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 1 1 1 Phenotypic Enhancement
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Phenotypic Enhancement
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Phenotypic Enhancement
HRB1 YNL004W Poly(A+) RNA-binding protein genetic 1 1 1 Negative Genetic
SNX4 YJL036W Sorting nexin genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Phenotypic Enhancement
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Phenotypic Enhancement
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Phenotypic Enhancement
CQD1 YPL109C UbiB family mitochondrial protein genetic 1 1 1 Negative Genetic
SHG1 YBR258C Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 1 1 1 Phenotypic Enhancement
VPS25 YJR102C Component of the ESCRT-II complex genetic 1 1 1 Phenotypic Enhancement
VPS28 YPL065W Component of the ESCRT-I complex genetic 1 1 1 Phenotypic Enhancement
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MCR1 YKL150W Mitochondrial NADH-cytochrome b5 reductase genetic 1 1 1 Negative Genetic
RPL13A YDL082W Ribosomal 60S subunit protein L13A genetic 1 1 1 Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Negative Genetic
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Phenotypic Enhancement
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
CSR1 YLR380W Phosphatidylinositol transfer protein physical 1 1 1 Affinity Capture-MS
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 1 1 1 Positive Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Negative Genetic
TGL2 YDR058C Triacylglycerol lipase that is localized to the mitochondria genetic 1 1 1 Negative Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Negative Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Phenotypic Enhancement
VTA1 YLR181C Multivesicular body (MVB) protein genetic 1 1 1 Phenotypic Enhancement
VPS3 YDR495C Component of CORVET membrane tethering complex genetic 1 1 1 Phenotypic Enhancement
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 1 1 1 Phenotypic Enhancement
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Phenotypic Enhancement
APT2 YDR441C Potential adenine phosphoribosyltransferase genetic 1 1 1 Negative Genetic
YPP1 YGR198W Cargo-transport protein involved in endocytosis physical 1 1 1 Affinity Capture-Western
YPT53 YNL093W Stress-induced Rab family GTPase genetic 1 1 1 Phenotypic Enhancement
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Phenotypic Enhancement
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
VPS36 YLR417W Component of the ESCRT-II complex genetic 1 1 1 Phenotypic Enhancement
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
THI3 YDL080C Regulatory protein that binds Pdc2p and Thi2p transcription factors genetic 1 1 1 Negative Genetic
YGL242C YGL242C Protein of unknown function genetic 1 1 1 Negative Genetic