ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
5 |
2 |
5 |
Co-purification, Co-purification, Co-purification, Co-purification, Affinity Capture-MS |
CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
3 |
2 |
3 |
Negative Genetic, Positive Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
2 |
2 |
Synthetic Haploinsufficiency, Negative Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SHE9 |
YDR393W |
Protein required for normal mitochondrial morphology |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
QCR9 |
YGR183C |
Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation- exonuclease evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HMS1 |
YOR032C |
bHLH protein with similarity to myc-family transcription factors |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HAP4 |
YKL109W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADK1 |
YDR226W |
Adenylate kinase, required for purine metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARE1 |
YCR048W |
Acyl-CoA:sterol acyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACF4 |
YJR083C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
ATG8 |
YBL078C |
Ub-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATP1 |
YBL099W |
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP4 |
YPL078C |
Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Co-purification |
ATP4 |
YPL078C |
Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
physical |
1 |
1 |
1 |
Biochemical Activity |
FRK1 |
YPL141C |
Protein kinase of unknown cellular role |
physical |
1 |
1 |
1 |
Biochemical Activity |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Two-hybrid |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
physical |
1 |
1 |
1 |
Two-hybrid |
BIT61 |
YJL058C |
Subunit of TORC2 membrane-associated complex |
physical |
1 |
1 |
1 |
Two-hybrid |
ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Protein-RNA |
ATP14 |
YLR295C |
Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ATP6 |
Q0085 |
Subunit a of the F0 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIC60 |
YKR016W |
Component of the MICOS complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ATP7 |
YKL016C |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATP7 |
YKL016C |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POM33 |
YLL023C |
Transmembrane nucleoporin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YAR029W |
YAR029W |
Member of DUP240 gene family but contains no transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
ATP15 |
YPL271W |
Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIM11 |
YDR322C-A |
Subunit e of mitochondrial F1F0-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FBP26 |
YJL155C |
Fructose-2,6-bisphosphatase, required for glucose metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYS3 |
YAL012W |
Cystathionine gamma-lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYS4 |
YGR155W |
Cystathionine beta-synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRP2 |
YER090W |
Anthranilate synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IPT1 |
YDR072C |
Inositolphosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PYC2 |
YBR218C |
Pyruvate carboxylase isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP5 |
YDR298C |
Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IDI1 |
YPL117C |
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE4 |
YLR146C |
Spermine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MET14 |
YKL001C |
Adenylylsulfate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRO2 |
YOR323C |
Gamma-glutamyl phosphate reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIB2 |
YOL066C |
Bifunctional DRAP deaminase tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP17 |
YDR377W |
Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MEP1 |
YGR121C |
Ammonium permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPH1 |
YPR160W |
Glycogen phosphorylase required for the mobilization of glycogen |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUT4 |
YOR348C |
Proline permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
URA2 |
YJL130C |
Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSH1 |
YBR161W |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
GRX1 |
YCL035C |
Glutathione-dependent disulfide oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
FUM1 |
YPL262W |
Fumarase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP14 |
YDL148C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUS1 |
YDL193W |
Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP6 |
YDR449C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCA1 |
YER168C |
ATP (CTP):tRNA-specific tRNA nucleotidyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDA1 |
YGR245C |
Protein required for actin organization and passage through Start |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLN1 |
YIL147C |
Transmembrane histidine phosphotransfer kinase and osmosensor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYR1 |
YJL005W |
Adenylate cyclase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAD2 |
YJL035C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP8 |
YOL144W |
Nucleolar protein required for 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VBA2 |
YBR293W |
Permease of basic amino acids in the vacuolar membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT5 |
YDL093W |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YSP2 |
YDR326C |
Sterol-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPQ2 |
YDR352W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NKP1 |
YDR383C |
Central kinetochore protein and subunit of the Ctf19 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFH5 |
YJL145W |
Unusual phosphatidylinositol transfer protein (PITP) that binds heme |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD7 |
YJR052W |
Nucleotide excision repair (NER) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTM1 |
YKL039W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSG1 |
YKL077W |
Protein that promotes the transport and maturation of Pma1 with Exp1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG5 |
YMR015C |
C-22 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL014W |
YOL014W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSK2 |
YOL045W |
PAS-domain containing serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAM3 |
YPL274W |
High-affinity S-adenosylmethionine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ALD4 |
YOR374W |
Mitochondrial aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
APA2 |
YDR530C |
Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II |
genetic |
1 |
1 |
1 |
Negative Genetic |