Standard name Systematic name Name description Description
FLO8 YER109C Transcription factor Transcription factor; required for flocculation, diploid filamentous growth, and haploid invasive growth; forms a heterodimer with Mss11p that interacts with the Swi/Snf complex during transcriptional activation of FLO1, FLO11, and STA1; S. cerevisiae genome reference strain S288C contains an internal in-frame stop at codon 142, which in other strains encodes tryptophan
Visualize the interactome of FLO8
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FLO8 6 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MSN1 YOL116W Transcriptional activator genetic 4 2 3 Dosage Rescue, Dosage Rescue, Dosage Rescue, Phenotypic Suppression
FLO11 YIR019C GPI-anchored cell surface glycoprotein (flocculin) regulation 3 3 3 beta-galactosidase reporter gene assay evidence, northern blot evidence, nucleic acid binding evidence
MSS11 YMR164C Transcription factor genetic 3 2 3 Dosage Rescue, Dosage Rescue, Phenotypic Suppression
SFL1 YOR140W Transcriptional repressor and activator genetic 3 2 3 Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression
MSS11 YMR164C Transcription factor physical 3 2 2 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade genetic 3 1 2 Dosage Rescue, Dosage Rescue, Dosage Rescue
SAC3 YDR159W mRNA export factor genetic 2 2 2 Phenotypic Suppression, Positive Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 2 1 2 Dosage Rescue, Dosage Rescue
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 2 1 2 Negative Genetic, Negative Genetic
YSP3 YOR003W Putative precursor of the subtilisin-like protease III genetic 2 1 2 Negative Genetic, Negative Genetic
FLO1 YAR050W Lectin-like protein involved in flocculation regulation 2 2 1 beta-galactosidase reporter gene assay evidence, chromatin immunoprecipitation-PCR evidence
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 2 1 1 Dosage Rescue, Dosage Rescue
SIS2 YKR072C Negative regulatory subunit of protein phosphatase 1 (Ppz1p) genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CMK2 YOL016C Calmodulin-dependent protein kinase regulation 1 1 1 DNA to cDNA expression microarray evidence
PST1 YDR055W Cell wall protein that contains a putative GPI-attachment site regulation 1 1 1 DNA to cDNA expression microarray evidence
YGP1 YNL160W Cell wall-related secretory glycoprotein regulation 1 1 1 DNA to cDNA expression microarray evidence
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II regulation 1 1 1 DNA to cDNA expression microarray evidence
CIP1 YPL014W Cyclin-dependent kinase inhibitor regulation 1 1 1 DNA to cDNA expression microarray evidence
HSP104 YLL026W Disaggregase regulation 1 1 1 DNA to cDNA expression microarray evidence
YDL023C YDL023C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
GLK1 YCL040W Glucokinase regulation 1 1 1 DNA to cDNA expression microarray evidence
GAD1 YMR250W Glutamate decarboxylase regulation 1 1 1 DNA to cDNA expression microarray evidence
GSY1 YFR015C Glycogen synthase regulation 1 1 1 DNA to cDNA expression microarray evidence
SPI1 YER150W GPI-anchored cell wall protein involved in weak acid resistance regulation 1 1 1 DNA to cDNA expression microarray evidence
NCW2 YLR194C GPI-anchored protein involved in cell wall remodeling regulation 1 1 1 DNA to cDNA expression microarray evidence
GYP7 YDL234C GTPase-activating protein for yeast Rab family members regulation 1 1 1 DNA to cDNA expression microarray evidence
CUP9 YPL177C Homeodomain-containing transcriptional repressor regulation 1 1 1 reporter gene assay evidence
TFS1 YLR178C Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p) regulation 1 1 1 DNA to cDNA expression microarray evidence
TSL1 YML100W Large subunit of trehalose 6-phosphate synthase/phosphatase complex regulation 1 1 1 DNA to cDNA expression microarray evidence
AIM23 YJL131C Mitochondrial translation initiation factor 3 (IF3, mIF3) regulation 1 1 1 DNA to cDNA expression microarray evidence
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p regulation 1 1 1 DNA to cDNA expression microarray evidence
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex regulation 1 1 1 DNA to cDNA expression microarray evidence
PGM2 YMR105C Phosphoglucomutase regulation 1 1 1 DNA to cDNA expression microarray evidence
TPO4 YOR273C Polyamine transporter of the major facilitator superfamily regulation 1 1 1 DNA to cDNA expression microarray evidence
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily regulation 1 1 1 DNA to cDNA expression microarray evidence
RGI1 YER067W Protein involved in energy metabolism under respiratory conditions regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR297W YLR297W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
PNS1 YOR161C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
TMA10 YLR327C Protein of unknown function that associates with ribosomes regulation 1 1 1 DNA to cDNA expression microarray evidence
YRO2 YBR054W Protein with a putative role in response to acid stress regulation 1 1 1 DNA to cDNA expression microarray evidence
YCL042W YCL042W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YDR365W-B YDR365W-B Retrotransposon TYA Gag and TYB Pol genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RIE1 YGR250C RNA binding protein and negative regulator of START regulation 1 1 1 DNA to cDNA expression microarray evidence
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity regulation 1 1 1 DNA to cDNA expression microarray evidence
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Synthetic Rescue
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Synthetic Rescue
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Dosage Rescue
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor genetic 1 1 1 Phenotypic Suppression
FIG1 YBR040W Integral membrane protein required for efficient mating genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Positive Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Negative Genetic
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade physical 1 1 1 Affinity Capture-Western
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression physical 1 1 1 Affinity Capture-Western
LTE1 YAL024C Protein similar to GDP/GTP exchange factors physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
MFG1 YDL233W Regulator of filamentous growth physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Reconstituted Complex
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Dosage Rescue
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth genetic 1 1 1 Dosage Rescue
KSS1 YGR040W Mitogen-activated protein kinase (MAPK) genetic 1 1 1 Dosage Rescue
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Synthetic Rescue
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Phenotypic Suppression
YDR124W YDR124W Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Negative Genetic
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 1 1 1 Dosage Rescue
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis genetic 1 1 1 Dosage Rescue
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Dosage Rescue
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Negative Genetic
TMH18 YPR098C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Phenotypic Suppression
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Phenotypic Suppression
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Positive Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Phenotypic Suppression
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Phenotypic Suppression
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) genetic 1 1 1 Phenotypic Suppression
TRK1 YJL129C Component of the Trk1p-Trk2p potassium transport system genetic 1 1 1 Phenotypic Suppression
TRK2 YKR050W Component of the Trk1p-Trk2p potassium transport system genetic 1 1 1 Phenotypic Suppression
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 1 1 1 Phenotypic Suppression
MTR10 YOR160W Nuclear import receptor genetic 1 1 1 Positive Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
GMH1 YKR030W Golgi membrane protein of unknown function genetic 1 1 1 Negative Genetic
SUR7 YML052W Plasma membrane protein, component of eisosomes genetic 1 1 1 Negative Genetic
IMP1 YMR150C Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
SPS4 YOR313C Protein whose expression is induced during sporulation genetic 1 1 1 Negative Genetic
SPO19 YPL130W Meiosis-specific prospore protein genetic 1 1 1 Negative Genetic
MRX4 YPL168W Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Phenotypic Suppression
RAD51 YER095W Strand exchange protein genetic 1 1 1 Negative Genetic
ARO80 YDR421W Zinc finger transcriptional activator of the Zn2Cys6 family genetic 1 1 1 Negative Genetic
FLO11 YIR019C GPI-anchored cell surface glycoprotein (flocculin) genetic 1 1 1 Phenotypic Enhancement
DNF2 YDR093W Aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
CTS1 YLR286C Endochitinase genetic 1 1 1 Dosage Rescue
AAD10 YJR155W Putative aryl-alcohol dehydrogenase genetic 1 1 1 Negative Genetic
FLO10 YKR102W Member of the FLO family of cell wall flocculation proteins genetic 1 1 1 Phenotypic Enhancement