| FUS2 |
YMR232W |
Cell fusion regulator |
genetic |
9 |
2 |
6 |
Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Dosage Rescue, Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement |
| SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
physical |
5 |
2 |
3 |
Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
4 |
2 |
3 |
Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement |
| BNR1 |
YIL159W |
Formin |
physical |
3 |
2 |
3 |
Two-hybrid, Protein-peptide, Two-hybrid |
| CHS5 |
YLR330W |
Component of the exomer complex |
physical |
3 |
3 |
2 |
Co-localization, Two-hybrid, Affinity Capture-Western |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression |
| STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
regulation |
2 |
2 |
2 |
beta-galactosidase reporter gene assay evidence, chromatin immunoprecipitation-chip evidence |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
1 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
| BNI1 |
YNL271C |
Formin |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| PEA2 |
YER149C |
Coiled-coil 12S polarisome subunit |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| GIP4 |
YAL031C |
Cytoplasmic protein that regulates protein phosphatase 1 Glc7p |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| SEG2 |
YKL105C |
Eisosome component |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| SIR1 |
YKR101W |
Protein involved in silencing at mating-type loci HML and HMR |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| HAA1 |
YPR008W |
Transcriptional activator involved in adaptation to weak acid stress |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| SPA2 |
YLL021W |
Component of the polarisome |
genetic |
2 |
2 |
1 |
Dosage Rescue, Phenotypic Enhancement |
| MID2 |
YLR332W |
O-glycosylated plasma membrane protein |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MSN1 |
YOL116W |
Transcriptional activator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HCM1 |
YCR065W |
Forkhead transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
regulation |
1 |
1 |
1 |
northern blot evidence |
| ARG81 |
YML099C |
Zinc finger transcription factor involved in arginine-responsive genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| ARO80 |
YDR421W |
Zinc finger transcriptional activator of the Zn2Cys6 family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
regulation |
1 |
1 |
1 |
northern blot evidence |
| STB3 |
YDR169C |
Ribosomal RNA processing element (RRPE)-binding protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
physical |
1 |
1 |
1 |
Two-hybrid |
| CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AXL1 |
YPR122W |
Haploid specific endoprotease of a-factor mating pheromone |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| BUD2 |
YKL092C |
GTPase activating factor for Rsr1p/Bud1p |
physical |
1 |
1 |
1 |
Two-hybrid |
| FIR1 |
YER032W |
Protein involved in 3' mRNA processing |
physical |
1 |
1 |
1 |
Two-hybrid |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| SPA2 |
YLL021W |
Component of the polarisome |
physical |
1 |
1 |
1 |
Co-localization |
| PSK1 |
YAL017W |
PAS domain-containing serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| ROM1 |
YGR070W |
Guanine nucleotide exchange factor (GEF) for Rho1p |
physical |
1 |
1 |
1 |
Two-hybrid |
| VAC7 |
YNL054W |
Integral vacuolar membrane protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| YNL058C |
YNL058C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| PET127 |
YOR017W |
Protein with a role in 5'-end processing of mitochondrial RNAs |
physical |
1 |
1 |
1 |
Two-hybrid |
| IMP4 |
YNL075W |
Component of the SSU processome |
physical |
1 |
1 |
1 |
Two-hybrid |
| RQT4 |
YKR023W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
physical |
1 |
1 |
1 |
Two-hybrid |
| STE5 |
YDR103W |
Pheromone-responsive MAPK scaffold protein |
physical |
1 |
1 |
1 |
Protein-peptide |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SIP5 |
YMR140W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
| GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Two-hybrid |
| MET31 |
YPL038W |
Zinc-finger DNA-binding transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
| PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
| MID1 |
YNL291C |
Stretch-activated Ca2+-permeable cation channel |
physical |
1 |
1 |
1 |
PCA |
| YDL199C |
YDL199C |
Putative transporter |
physical |
1 |
1 |
1 |
PCA |
| MAL11 |
YGR289C |
High-affinity maltose transporter (alpha-glucoside transporter) |
physical |
1 |
1 |
1 |
PCA |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
physical |
1 |
1 |
1 |
PCA |
| LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| PRM1 |
YNL279W |
Pheromone-regulated multispanning membrane protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
| YNK1 |
YKL067W |
Nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTA1 |
YLR181C |
Multivesicular body (MVB) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCW2 |
YLR194C |
GPI-anchored protein involved in cell wall remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCL8 |
YPL219W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MMT2 |
YPL224C |
Putative metal transporter involved in mitochondrial iron accumulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HXT6 |
YDR343C |
High-affinity glucose transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM13 |
YOL125W |
2'-O-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| KEL2 |
YGR238C |
Protein that negatively regulates mitotic exit |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| EMP70 |
YLR083C |
Protein with a role in cellular adhesion and filamentous growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
physical |
1 |
1 |
1 |
PCA |
| APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |