Standard name Systematic name Name description Description
SGD1 YLR336C Essential nuclear protein Essential nuclear protein; required for biogenesis of the small ribosomal subunit; has a possible role in the osmoregulatory glycerol response; putative homolog of human NOM1 which is implicated in acute myeloid leukemia
Visualize the interactome of SGD1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.051 NaN NaN
Nucleolus 0.897 0.798 0.845
Nucleus 0.158 0.269 0.217
SpindlePole 0.128 0.067 0.353

GFP localization & abundance

GFP localization GFP abundance
nucleolus 3060

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SGD1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA physical 5 3 3 Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex
RRP9 YPR137W Protein involved in pre-rRNA processing physical 4 3 3 PCA, Two-hybrid, Two-hybrid, Reconstituted Complex
LCP5 YER127W Essential protein involved in maturation of 18S rRNA physical 3 2 2 Two-hybrid, Two-hybrid, Affinity Capture-Western
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 3 3 1 Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 2 2 2 Affinity Capture-MS, Two-hybrid
NOC4 YPR144C Nucleolar protein physical 2 2 2 Affinity Capture-MS, Two-hybrid
UTP10 YJL109C Nucleolar protein physical 2 2 2 Affinity Capture-MS, Two-hybrid
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 2 2 2 Dosage Rescue, Synthetic Lethality
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 2 1 2 Negative Genetic, Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 2 1 2 Negative Genetic, Negative Genetic
RRP36 YOR287C Component of 90S preribosomes physical 2 1 2 Two-hybrid, Two-hybrid
PLC1 YPL268W Phospholipase C physical 2 2 1 Affinity Capture-Western, Two-hybrid
PLC1 YPL268W Phospholipase C genetic 2 2 1 Dosage Rescue, Synthetic Growth Defect
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing physical 2 1 1 Two-hybrid, Two-hybrid
UTP6 YDR449C Nucleolar protein physical 2 1 1 Two-hybrid, Two-hybrid
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RSF2 YJR127C Zinc-finger protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
INO4 YOL108C Transcription factor involved in phospholipid synthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Two-hybrid
DIP2 YLR129W Nucleolar protein physical 1 1 1 Two-hybrid
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 1 1 1 Negative Genetic
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Two-hybrid
HCA4 YJL033W DEAD box RNA helicase physical 1 1 1 Two-hybrid
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
MUD1 YBR119W U1 snRNP A protein genetic 1 1 1 Negative Genetic
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
ENP1 YBR247C Protein associated with U3 and U14 snoRNAs physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
AEP2 YMR282C Mitochondrial protein genetic 1 1 1 Negative Genetic
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 1 1 1 Two-hybrid
MPP10 YJR002W Component of the SSU processome and 90S preribosome physical 1 1 1 Two-hybrid
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Negative Genetic
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
ESF2 YNR054C Essential nucleolar protein involved in pre-18S rRNA processing physical 1 1 1 Two-hybrid
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
ROK1 YGL171W RNA-dependent ATPase physical 1 1 1 Reconstituted Complex
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Dosage Rescue
PXR1 YGR280C Essential protein involved in rRNA and snoRNA maturation physical 1 1 1 Two-hybrid
ATG12 YBR217W Ubiquitin-like modifier involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
ZUO1 YGR285C Ribosome-associated chaperone physical 1 1 1 Affinity Capture-MS
YAP3 YHL009C Basic leucine zipper (bZIP) transcription factor physical 1 1 1 PCA
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Affinity Capture-MS
SQS1 YNL224C Protein that stimulates the ATPase and helicase activities of Prp43p physical 1 1 1 Two-hybrid
SGD1 YLR336C Essential nuclear protein physical 1 1 1 Two-hybrid
SLX9 YGR081C Protein required for pre-rRNA processing physical 1 1 1 Two-hybrid
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation physical 1 1 1 Two-hybrid
UTP30 YKR060W Subunit of U3-containing 90S preribosome complex physical 1 1 1 Two-hybrid
UTP30 YKR060W Subunit of U3-containing 90S preribosome complex genetic 1 1 1 Negative Genetic
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Lethality
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
DHR2 YKL078W Predominantly nucleolar DEAH-box ATP-dependent RNA helicase physical 1 1 1 Two-hybrid
ATG16 YMR159C Conserved protein involved in autophagy genetic 1 1 1 Negative Genetic
PEF1 YGR058W Penta-EF-hand protein genetic 1 1 1 Negative Genetic
PEX13 YLR191W Peroxisomal importomer complex component genetic 1 1 1 Negative Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
ARO8 YGL202W Aromatic aminotransferase I genetic 1 1 1 Negative Genetic
CAT2 YML042W Carnitine acetyl-CoA transferase genetic 1 1 1 Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family physical 1 1 1 Affinity Capture-MS
NOP19 YGR251W Ribosome biogenesis factor physical 1 1 1 Two-hybrid
SAS10 YDL153C Subunit of U3-containing Small Subunit (SSU) processome complex physical 1 1 1 Two-hybrid
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Negative Genetic
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum genetic 1 1 1 Negative Genetic
MRX19 YDL183C Protein that may form an active mitochondrial KHE system genetic 1 1 1 Positive Genetic