Standard name Systematic name Name description Description
SPC34 YKR037C Essential subunit of the Dam1 complex (aka DASH complex) Essential subunit of the Dam1 complex (aka DASH complex); complex couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; also localized to nuclear side of spindle pole body
Visualize the interactome of SPC34
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 148

CYCLoPs localization & abundance

WT1 WT2 WT3
Budsite 0.051 NaN NaN
Cytoplasm 0.076 0.388 0.984
Mito 0.056 0.059 NaN
Nucleolus 0.487 0.180 NaN
Peroxisome 0.076 0.075 NaN
SpindlePole 0.726 0.459 NaN

GFP localization & abundance

GFP localization GFP abundance
spindle pole technical problem

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SPC34 0 3 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) physical 16 5 13 Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Co-fractionation, Affinity Capture-MS, Co-purification, Two-hybrid, Two-hybrid, Two-hybrid, Co-purification, Co-purification, Two-hybrid, Two-hybrid, Reconstituted Complex
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) physical 15 5 11 Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Co-purification, Two-hybrid, Two-hybrid, Co-purification, Co-purification, Two-hybrid, Two-hybrid, Reconstituted Complex
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) physical 13 5 12 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Co-purification, Co-purification, Two-hybrid, Two-hybrid, Co-purification, Co-purification, Two-hybrid, Reconstituted Complex
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) physical 13 4 10 Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Co-fractionation, Co-purification, Two-hybrid, Two-hybrid, Co-purification, Co-purification, Two-hybrid, Two-hybrid, Reconstituted Complex
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) physical 8 4 8 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Co-purification, Co-purification, Reconstituted Complex
HSK3 YKL138C-A Essential subunit of the Dam1 complex (aka DASH complex) physical 7 4 7 Co-purification, Affinity Capture-MS, Co-purification, Two-hybrid, Co-purification, Co-purification, Reconstituted Complex
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) physical 6 4 6 Affinity Capture-MS, Co-purification, Two-hybrid, Co-purification, Co-purification, Reconstituted Complex
DAD4 YDR320C-A Essential subunit of the Dam1 complex (aka DASH complex) physical 5 4 5 Affinity Capture-MS, Co-purification, Two-hybrid, Co-purification, Reconstituted Complex
DAD3 YBR233W-A Essential subunit of the Dam1 complex (aka DASH complex) physical 5 3 5 Co-purification, Two-hybrid, Co-purification, Co-purification, Reconstituted Complex
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Synthetic Lethality, Positive Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 2 2 2 Co-purification, Reconstituted Complex
FKH1 YIL131C Forkhead family transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 2 1 2 Biochemical Activity, Biochemical Activity
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family physical 2 1 1 Two-hybrid, Two-hybrid
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) physical 2 1 1 Two-hybrid, Two-hybrid
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HCM1 YCR065W Forkhead transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 1 1 1 Synthetic Lethality
CTF3 YLR381W Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p genetic 1 1 1 Synthetic Growth Defect
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 1 1 1 Synthetic Lethality
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Synthetic Lethality
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization physical 1 1 1 Two-hybrid
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
KSP1 YHR082C Serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Synthetic Growth Defect
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Synthetic Lethality
BIM1 YER016W Microtubule plus end-tracking protein physical 1 1 1 Two-hybrid
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Synthetic Lethality
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Synthetic Lethality
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Reconstituted Complex
JSN1 YJR091C Member of the Puf family of RNA-binding proteins physical 1 1 1 Two-hybrid
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Synthetic Growth Defect
RFT1 YBL020W Membrane protein required for translocation of Man5GlcNac2-PP-Dol genetic 1 1 1 Synthetic Growth Defect
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Lethality
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Synthetic Growth Defect
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Synthetic Growth Defect
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 1 1 1 Co-purification
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
SPC34 YKR037C Essential subunit of the Dam1 complex (aka DASH complex) physical 1 1 1 Reconstituted Complex
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 PCA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Synthetic Growth Defect
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Synthetic Growth Defect
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
CNN1 YFR046C Kinetochore protein physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
NPY1 YGL067W NADH diphosphatase (pyrophosphatase) physical 1 1 1 Affinity Capture-MS
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Synthetic Growth Defect
SHE1 YBL031W Mitotic spindle protein physical 1 1 1 Two-hybrid
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 1 1 1 Synthetic Growth Defect