Standard name Systematic name Name description Description
TPO4 YOR273C Polyamine transporter of the major facilitator superfamily Polyamine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane
Visualize the interactome of TPO4
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G2/M 141

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.105 0.080 NaN
Cell Periphery 0.602 0.780 0.864
Cort. Patches 0.293 0.344 0.388
Cytoplasm 0.331 0.190 0.080
Mito 0.158 0.085 0.257

GFP localization & abundance

GFP localization GFP abundance
cell periphery, bud 21400

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TPO4 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1261 (spermidine transport), r_1251 (putrescine transport), r_1252 (putrescine transport), r_1260 (spermidine transport), r_1262 (spermine transport), r_1263 (spermine transport)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
MHP1 YJL042W Microtubule-associated protein involved in microtubule organization genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
MSN2 YMR037C Stress-responsive transcriptional activator regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
YGR130C YGR130C Component of the eisosome with unknown function physical 2 1 2 PCA, PCA
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Positive Genetic, Positive Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 2 1 1 Negative Genetic, Negative Genetic
TPA1 YER049W Prolyl hydroxylase genetic 2 1 1 Negative Genetic, Negative Genetic
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 1 Negative Genetic, Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 2 1 1 Negative Genetic, Negative Genetic
RMA1 YKL132C Putative dihydrofolate synthetase genetic 2 1 1 Negative Genetic, Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 2 1 1 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ZAP1 YJL056C Zinc-regulated transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
NRG1 YDR043C Transcriptional repressor regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT2 YER161C Protein involved in negative regulation of transcription regulation 1 1 1 DNA to cDNA expression microarray evidence
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GAT3 YLR013W Protein containing GATA family zinc finger motifs regulation 1 1 1 DNA to cDNA expression microarray evidence
MAC1 YMR021C Copper-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
RGM1 YMR182C Putative zinc finger DNA binding transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
WTM2 YOR229W Transcriptional modulator regulation 1 1 1 DNA to cDNA expression microarray evidence
INO4 YOL108C Transcription factor involved in phospholipid synthesis regulation 1 1 1 DNA to cDNA expression microarray evidence
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis regulation 1 1 1 DNA to cDNA expression microarray evidence
YHP1 YDR451C Homeobox transcriptional repressor regulation 1 1 1 DNA to cDNA expression microarray evidence
RPH1 YER169W JmjC domain-containing histone demethylase regulation 1 1 1 DNA to cDNA expression microarray evidence
OAF1 YAL051W Oleate-activated transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CUP2 YGL166W Copper-binding transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
FLO8 YER109C Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
MBF1 YOR298C-A Transcriptional coactivator regulation 1 1 1 DNA to cDNA expression microarray evidence
KAP123 YER110C Karyopherin beta genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
LSP1 YPL004C Eisosome core component physical 1 1 1 PCA
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins physical 1 1 1 PCA
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein physical 1 1 1 PCA
FUB1 YCR076C Proteasome-binding protein genetic 1 1 1 Negative Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 1 1 1 PCA
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase physical 1 1 1 PCA
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
COX18 YGR062C Protein required for membrane insertion of C-terminus of Cox2p genetic 1 1 1 Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane physical 1 1 1 PCA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 PCA
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine physical 1 1 1 PCA
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance physical 1 1 1 PCA
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Negative Genetic
PLM2 YDR501W Putative transcription factor, contains Forkhead Associated domain physical 1 1 1 PCA
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Negative Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
FTR1 YER145C High affinity iron permease physical 1 1 1 PCA
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
GIP4 YAL031C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p genetic 1 1 1 Negative Genetic
MRPL32 YCR003W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MUB1 YMR100W MYND domain-containing protein genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
DGR2 YKL121W Protein of unknown function genetic 1 1 1 Negative Genetic
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase physical 1 1 1 PCA
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Negative Genetic
OSH6 YKR003W Oxysterol-binding phosphatidylserine transferase physical 1 1 1 PCA
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Positive Genetic
MUP1 YGR055W High affinity methionine permease physical 1 1 1 PCA
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p physical 1 1 1 PCA
FLC1 YPL221W Flavin adenine dinucleotide transporter physical 1 1 1 PCA
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
UIP3 YAR027W Putative integral membrane protein of unknown function physical 1 1 1 PCA
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Affinity Capture-RNA
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
UBA3 YPR066W Protein that activates Rub1p (NEDD8) before neddylation genetic 1 1 1 Negative Genetic
YGR210C YGR210C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
PET117 YER058W Assembly factor that couples heme a synthesis to complex IV assembly genetic 1 1 1 Negative Genetic
PUG1 YER185W Plasma membrane protein involved in protoprophyrin and heme transport genetic 1 1 1 Negative Genetic