Standard name Systematic name Name description Description
VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase Mitochondrial and cytoplasmic valyl-tRNA synthetase; human homolog VARS2 implicated in mitochondrial diseases, can partially complement yeast null mutant
Visualize the interactome of VAS1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 1.0 0.982 0.987

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 358

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
VAS1 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1090 (valyl-tRNA synthetase), r_1089 (valyl-tRNA synthetase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
HSP82 YPL240C Hsp90 chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
ZAP1 YJL056C Zinc-regulated transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 DNA to cDNA expression microarray evidence
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Positive Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
MRP1 YDR347W Mitochondrial ribosomal protein of the small subunit physical 1 1 1 Proximity Label-MS
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 Two-hybrid
CMD1 YBR109C Calmodulin physical 1 1 1 Affinity Capture-MS
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Two-hybrid
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
RNH1 YMR234W Ribonuclease H1 physical 1 1 1 Affinity Capture-MS
SER3 YER081W 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase genetic 1 1 1 Negative Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
GLN1 YPR035W Glutamine synthetase (GS) genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 1 1 1 Biochemical Activity
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Dosage Growth Defect
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 1 1 1 Positive Genetic
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Negative Genetic
ADH2 YMR303C Glucose-repressible alcohol dehydrogenase II genetic 1 1 1 Positive Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Co-localization
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex physical 1 1 1 Affinity Capture-MS
SAC3 YDR159W mRNA export factor physical 1 1 1 Two-hybrid
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
PRK1 YIL095W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Positive Genetic
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Two-hybrid
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase physical 1 1 1 Two-hybrid
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Two-hybrid
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Positive Genetic
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
PIN3 YPR154W Negative regulator of actin nucleation-promoting factor activity physical 1 1 1 Two-hybrid
COQ3 YOL096C O-methyltransferase genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer physical 1 1 1 Affinity Capture-MS
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex physical 1 1 1 Two-hybrid
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) physical 1 1 1 Affinity Capture-MS
POX1 YGL205W Fatty-acyl coenzyme A oxidase genetic 1 1 1 Positive Genetic
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase genetic 1 1 1 Negative Genetic
PNP1 YLR209C Purine nucleoside phosphorylase genetic 1 1 1 Negative Genetic
COQ4 YDR204W Protein with a role in ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
BAP2 YBR068C High-affinity leucine permease genetic 1 1 1 Negative Genetic
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 Affinity Capture-MS
BUD16 YEL029C Putative pyridoxal kinase genetic 1 1 1 Positive Genetic
PMP1 YCR024C-A Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p physical 1 1 1 Affinity Capture-RNA
BCD1 YHR040W Essential protein required for the accumulation of box C/D snoRNA genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER physical 1 1 1 Affinity Capture-MS
IDP2 YLR174W Cytosolic NADP-specific isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Negative Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Positive Genetic
YBR071W YBR071W Protein of unknown function found in the cytoplasm and bud neck genetic 1 1 1 Negative Genetic
YMR295C YMR295C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
MIN3 YMR182W-A Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic