Standard name Systematic name Name description Description
ALY1 YKR021W Alpha arrestin, substrate of calcineurin Alpha arrestin, substrate of calcineurin; controls nutrient-mediated intracellular sorting of permease Gap1p; interacts with AP-1 subunit Apl4p; dephosphorylation of Aly1p required for the endocytosis of Dip5p; may regulate endocytosis of plasma membrane proteins by recruiting ubiquitin ligase Rsp5p to plasma membrane targets; ALY1 has a paralog, ALY2, that arose from the whole genome duplication
Visualize the interactome of ALY1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G2 114

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.983 0.984 0.977

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ALY1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 6 4 5 Biochemical Activity, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
CNA1 YLR433C Calcineurin A physical 5 4 2 Two-hybrid, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Biochemical Activity
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p genetic 3 2 3 Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement
BMH2 YDR099W 14-3-3 protein, minor isoform physical 2 2 2 Co-purification, Two-hybrid
YDR124W YDR124W Mitochondrial protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
BUL1 YMR275C Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins physical 2 1 1 Reconstituted Complex, Reconstituted Complex
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
LEU3 YLR451W Zinc-knuckle transcription factor, repressor and activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LSM8 YJR022W Lsm (Like Sm) protein physical 1 1 1 Two-hybrid
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase physical 1 1 1 Biochemical Activity
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 1 1 1 Affinity Capture-MS
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Affinity Capture-MS
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
GAP1 YKR039W General amino acid permease physical 1 1 1 Affinity Capture-Western
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-Western
APL2 YKL135C Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex physical 1 1 1 Affinity Capture-Western
APL4 YPR029C Gamma-adaptin physical 1 1 1 Affinity Capture-Western
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity physical 1 1 1 Reconstituted Complex
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 Co-purification
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CMP2 YML057W Calcineurin A physical 1 1 1 Reconstituted Complex
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
THR1 YHR025W Homoserine kinase genetic 1 1 1 Dosage Rescue
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Synthetic Rescue
NPR1 YNL183C Protein kinase genetic 1 1 1 Dosage Growth Defect
LDB19 YOR322C Alpha-arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Phenotypic Enhancement
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
DNF2 YDR093W Aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
GCG1 YER163C Gamma-glutamyl cyclotransferase genetic 1 1 1 Negative Genetic
BUD9 YGR041W Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
YBT1 YLL048C Transporter of the ATP-binding cassette (ABC) family genetic 1 1 1 Negative Genetic
FMS1 YMR020W Polyamine oxidase genetic 1 1 1 Negative Genetic
GNT1 YOR320C N-acetylglucosaminyltransferase genetic 1 1 1 Negative Genetic
TKL1 YPR074C Transketolase genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Negative Genetic