Standard name Systematic name Name description Description
DRE2 YKR071C Component of the cytosolic Fe-S protein assembly (CIA) machinery Component of the cytosolic Fe-S protein assembly (CIA) machinery; contains an Fe-S cluster that receives electrons from NADPH via the action of Tah18p in an early step in the CIA pathway; ortholog of human Ciapin1; protein abundance increases in response to DNA replication stress; inviability of the null mutant is functionally complemented by human CIAPIN1
Visualize the interactome of DRE2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.983 1.0 1.0

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 1050

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
DRE2 3 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
TAH18 YPR048W Conserved NAPDH-dependent diflavin reductase physical 8 5 6 Affinity Capture-MS, PCA, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-Western
TAH18 YPR048W Conserved NAPDH-dependent diflavin reductase genetic 3 2 2 Dosage Rescue, Synthetic Lethality, Dosage Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
STB5 YHR178W Transcription factor regulation 2 2 1 chromatin immunoprecipitation- exonuclease evidence, RNA-sequencing evidence
MRS3 YJL133W Iron transporter, mediates Fe2+ transport across inner mito membrane genetic 2 2 1 Synthetic Lethality, Dosage Lethality
MRS4 YKR052C Iron transporter of the mitochondrial carrier family genetic 2 2 1 Synthetic Lethality, Dosage Lethality
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination physical 1 1 1 Affinity Capture-MS
SES1 YDR023W Cytosolic seryl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Biochemical Activity
SKY1 YMR216C SR protein kinase (SRPK) physical 1 1 1 Biochemical Activity
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Biochemical Activity
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Biochemical Activity
TOS3 YGL179C Protein kinase physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
FRK1 YPL141C Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
GRX3 YDR098C Glutathione-dependent oxidoreductase physical 1 1 1 PCA
GRX3 YDR098C Glutathione-dependent oxidoreductase genetic 1 1 1 Synthetic Growth Defect
UBI4 YLL039C Ubiquitin physical 1 1 1 Affinity Capture-MS
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint physical 1 1 1 Reconstituted Complex
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly physical 1 1 1 Reconstituted Complex
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
NBP35 YGL091C Essential cytoplasmic iron-sulfur cluster binding protein physical 1 1 1 Affinity Capture-Western
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery physical 1 1 1 Affinity Capture-Western
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit physical 1 1 1 Affinity Capture-Western
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
GRX4 YER174C Glutathione-dependent oxidoreductase and glutathione S-transferase genetic 1 1 1 Synthetic Growth Defect
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Synthetic Growth Defect
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 1 1 1 Phenotypic Suppression
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Phenotypic Suppression
CFD1 YIL003W Highly conserved iron-sulfur cluster binding protein physical 1 1 1 Affinity Capture-Western
AFT2 YPL202C Iron-regulated transcriptional activator genetic 1 1 1 Phenotypic Suppression