| OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FAT1 |
YBR041W |
Very long chain fatty acyl-CoA synthetase and fatty acid transporter |
physical |
2 |
2 |
2 |
Co-fractionation, PCA |
| EHT1 |
YBR177C |
Octanoyl-CoA:ethanol acyltransferase |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Reconstituted Complex |
| BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MSS2 |
YDL107W |
Peripherally bound inner membrane protein of the mitochondrial matrix |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TMS1 |
YDR105C |
Vacuolar membrane protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FIN1 |
YDR130C |
Spindle pole body-related intermediate filament protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| OYE2 |
YHR179W |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YJL206C |
YJL206C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| YME2 |
YMR302C |
Integral inner mitochondrial membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MEK1 |
YOR351C |
Meiosis-specific serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PPT2 |
YPL148C |
Phosphopantetheine:protein transferase (PPTase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COA4 |
YLR218C |
Twin Cx(9)C protein involved in cytochrome c oxidase organization |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CYC8 |
YBR112C |
General transcriptional co-repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CAR1 |
YPL111W |
Arginase, catabolizes arginine to ornithine and urea |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM29 |
YHL030W |
Scaffold protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
physical |
1 |
1 |
1 |
Two-hybrid |
| CMP2 |
YML057W |
Calcineurin A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| AYR1 |
YIL124W |
Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase |
physical |
1 |
1 |
1 |
PCA |
| CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| ALR1 |
YOL130W |
Plasma membrane Mg(2+) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCH1 |
YMR237W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACF2 |
YLR144C |
Intracellular beta-1,3-endoglucanase |
physical |
1 |
1 |
1 |
PCA |
| ATF1 |
YOR377W |
Alcohol acetyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MYO5 |
YMR109W |
One of two type I myosin motors |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
physical |
1 |
1 |
1 |
Co-purification |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
physical |
1 |
1 |
1 |
Co-purification |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
physical |
1 |
1 |
1 |
PCA |
| INO1 |
YJL153C |
Inositol-3-phosphate synthase |
physical |
1 |
1 |
1 |
PCA |
| SNA3 |
YJL151C |
Protein involved in efficient MVB sorting of proteins to the vacuole |
physical |
1 |
1 |
1 |
PCA |
| PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
physical |
1 |
1 |
1 |
PCA |
| VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
PCA |
| ERG7 |
YHR072W |
Lanosterol synthase |
physical |
1 |
1 |
1 |
PCA |
| KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
physical |
1 |
1 |
1 |
PCA |
| TCD1 |
YHR003C |
tRNA threonylcarbamoyladenosine dehydratase |
physical |
1 |
1 |
1 |
PCA |
| GDI1 |
YER136W |
GDP dissociation inhibitor |
physical |
1 |
1 |
1 |
PCA |
| YEH1 |
YLL012W |
Steryl ester hydrolase |
physical |
1 |
1 |
1 |
PCA |
| TOM20 |
YGR082W |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
PCA |
| TGL1 |
YKL140W |
Steryl ester hydrolase |
physical |
1 |
1 |
1 |
PCA |
| YJU3 |
YKL094W |
Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters |
physical |
1 |
1 |
1 |
PCA |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSK2 |
YOL045W |
PAS-domain containing serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SKM1 |
YOL113W |
Member of the PAK family of serine/threonine protein kinases |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Protein-peptide |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Two-hybrid |
| YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HGH1 |
YGR187C |
Chaperone protein for translation factor eEF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOM22 |
YNL131W |
Component of the TOM (Translocase of Outer Membrane) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SRF1 |
YDL133W |
Regulator of phospholipase D (Spo14p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TES1 |
YJR019C |
Peroxisomal acyl-CoA thioesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUT2 |
YPR009W |
Zn2Cys6 family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIN10 |
YFR032C-B |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STF2 |
YGR008C |
Protein involved in resistance to desiccation stress |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSA4 |
YCR072C |
Ribosomal large subunit (60S) assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTR3 |
YGR158C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP4 |
YHR069C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV12 |
YOR183W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM8 |
YDL201W |
Catalytic subunit of a tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRH1 |
YDR033W |
Protein that localizes primarily to the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHM6 |
YDR281C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPS7 |
YDR349C |
Putative GPI-anchored aspartic protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOR1 |
YDR366C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCY21 |
YER060W |
Putative purine-cytosine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VFA1 |
YER128W |
Protein that interacts with Vps4p and has a role in vacuolar sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA22 |
YHR060W |
Protein that is required for vacuolar H+-ATPase (V-ATPase) function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UFO1 |
YML088W |
F-box receptor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCH1 |
YMR034C |
Negative regulator of cytosolic calcium homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTG1 |
YMR097C |
Putative GTPase peripheral to the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HFA1 |
YMR207C |
Mitochondrial acetyl-coenzyme A carboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RDL2 |
YOR286W |
Protein with rhodanese activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR10 |
YOR328W |
ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD17 |
YOR368W |
Checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RDR1 |
YOR380W |
Transcriptional repressor involved in regulating multidrug resistance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ11 |
YLR290C |
Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM23 |
YJL131C |
Mitochondrial translation initiation factor 3 (IF3, mIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATF2 |
YGR177C |
Alcohol acetyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| APS2 |
YJR058C |
Small subunit of the clathrin-associated adaptor complex AP-2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALO1 |
YML086C |
D-Arabinono-1,4-lactone oxidase |
physical |
1 |
1 |
1 |
PCA |
| ALO1 |
YML086C |
D-Arabinono-1,4-lactone oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX20 |
YDR231C |
Mitochondrial inner membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DPI8 |
YJL133C-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BER1 |
YLR412W |
Protein involved in microtubule-related processes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAT1 |
YKL106W |
Mitochondrial aspartate aminotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
