Standard name Systematic name Name description Description
MSL1 YIR009W U2B component of U2 snRNP U2B component of U2 snRNP; involved in splicing, binds the U2 snRNA stem-loop IV in vitro but requires association of Lea1p for in vivo binding; does not contain the conserved C-terminal RNA binding domain found in other family members
Visualize the interactome of MSL1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm NaN NaN 0.500
Mito NaN NaN 0.406
Nucleus NaN NaN 0.188
Vac/Vac Memb NaN NaN 0.094

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 504

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MSL1 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LEA1 YPL213W Component of U2 snRNP complex physical 9 4 6 Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CEF1 YMR213W Essential splicing factor physical 3 3 3 Affinity Capture-MS, Reconstituted Complex, Co-purification
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP19 YLL036C Splicing factor associated with the spliceosome physical 2 2 2 Affinity Capture-MS, Co-purification
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects physical 2 1 2 Two-hybrid, Two-hybrid
SMB1 YER029C Core Sm protein Sm B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SMX3 YPR182W Core Sm protein Sm F genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 2 2 1 Phenotypic Enhancement, Synthetic Growth Defect
SMD2 YLR275W Core Sm protein Sm D2 genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
SMX2 YFL017W-A Core Sm protein Sm G genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
SME1 YOR159C Core Sm protein Sm E genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MPS3 YJL019W Nuclear envelope protein genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CWC2 YDL209C Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Lethality
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Phenotypic Enhancement
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member physical 1 1 1 Two-hybrid
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Synthetic Lethality
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Synthetic Lethality
SMX3 YPR182W Core Sm protein Sm F physical 1 1 1 Affinity Capture-MS
PRP46 YPL151C Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
SNT309 YPR101W Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
TAF4 YMR005W TFIID subunit (48 kDa) physical 1 1 1 Affinity Capture-MS
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Synthetic Growth Defect
PET127 YOR017W Protein with a role in 5'-end processing of mitochondrial RNAs physical 1 1 1 Two-hybrid
PET309 YLR067C Specific translational activator for the COX1 mRNA physical 1 1 1 Two-hybrid
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 1 1 1 Two-hybrid
NCE103 YNL036W Carbonic anhydrase physical 1 1 1 Two-hybrid
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 1 1 1 Two-hybrid
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Lethality
SSL2 YIL143C Component of RNA polymerase transcription factor TFIIH holoenzyme physical 1 1 1 Two-hybrid
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Two-hybrid
RMD1 YDL001W Cytoplasmic protein required for sporulation physical 1 1 1 Two-hybrid
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes physical 1 1 1 Two-hybrid
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes physical 1 1 1 Two-hybrid
YLR456W YLR456W Protein of unknown function physical 1 1 1 Two-hybrid
RAD16 YBR114W Nucleotide excision repair (NER) protein physical 1 1 1 Two-hybrid
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway physical 1 1 1 Affinity Capture-MS
PRP2 YNR011C RNA-dependent DExD/H-box ATPase physical 1 1 1 Affinity Capture-MS
PRP16 YKR086W DEAH-box RNA helicase physical 1 1 1 Affinity Capture-MS
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 1 1 1 Co-purification
YJU2 YKL095W Essential protein required for pre-mRNA splicing physical 1 1 1 Reconstituted Complex
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Synthetic Lethality
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 1 1 1 Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Synthetic Growth Defect
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Lethality
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Synthetic Lethality
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Synthetic Growth Defect
MUD1 YBR119W U1 snRNP A protein genetic 1 1 1 Synthetic Lethality
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Synthetic Rescue
LTE1 YAL024C Protein similar to GDP/GTP exchange factors physical 1 1 1 Two-hybrid
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Rescue
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
HTB1 YDR224C Histone H2B genetic 1 1 1 Synthetic Lethality
CNA1 YLR433C Calcineurin A physical 1 1 1 Two-hybrid
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Synthetic Growth Defect
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 genetic 1 1 1 Synthetic Lethality
BAS1 YKR099W Myb-related transcription factor physical 1 1 1 Two-hybrid
CDC26 YFR036W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) genetic 1 1 1 Synthetic Lethality
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
BIK1 YCL029C Microtubule-associated protein genetic 1 1 1 Synthetic Growth Defect
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
BUD6 YLR319C Actin- and formin-interacting protein genetic 1 1 1 Dosage Rescue
ATC1 YDR184C Nuclear protein physical 1 1 1 Two-hybrid
ATC1 YDR184C Nuclear protein genetic 1 1 1 Dosage Rescue
HHT2 YNL031C Histone H3 genetic 1 1 1 Synthetic Lethality
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
AUS1 YOR011W Plasma membrane sterol transporter of the ATP-binding cassette family physical 1 1 1 Two-hybrid
KIP2 YPL155C Kinesin-related motor protein involved in mitotic spindle positioning genetic 1 1 1 Dosage Rescue
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Synthetic Lethality