Standard name Systematic name Name description Description
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein Mitotic exit network (MEN) scaffold protein; core component of the SPB outer plaque that functions in astral microtubule organization via Spc72p; scaffold for recruitment of MEN components, such as Cdc15p, Tem1p and the Bfa1p-Bub2p checkpoint complex; phosphorylation by Cdc15p creates a Dbf2p-Mob1p phospho-docking site enabling Cdc15p-dependent complex activation and mitotic exit; acts through the MEN to specify Kar9p-mediated asymmetric SPB inheritance; homologous to mammalian centriolin
Visualize the interactome of NUD1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1/S 44

CYCLoPs localization & abundance

WT1 WT2 WT3
Budsite 0.061 NaN NaN
Nucleolus 0.168 0.075 0.052
Peroxisome 0.101 0.099 NaN
SpindlePole 0.859 0.860 0.876
Endosome NaN 0.061 NaN
Cytoplasm NaN NaN 0.060

GFP localization & abundance

GFP localization GFP abundance
spindle pole 892

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NUD1 0 10 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKH1 YIL131C Forkhead family transcription factor regulation 5 3 5 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 4 3 3 Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Reconstituted Complex
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p physical 4 3 3 Affinity Capture-Western, Co-localization, FRET, Affinity Capture-Western
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 3 3 3 Co-localization, Two-hybrid, Proximity Label-MS
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 3 2 3 Biochemical Activity, Biochemical Activity, Reconstituted Complex
MOB1 YIL106W Component of the mitotic exit network physical 3 3 2 Affinity Capture-Western, Reconstituted Complex, Proximity Label-MS
CNM67 YNL225C Component of the spindle pole body outer plaque physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid
BUB2 YMR055C Mitotic exit network regulator physical 3 3 1 Affinity Capture-Western, Two-hybrid, Co-localization
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 2 2 2 Affinity Capture-Western, Co-purification
SPC42 YKL042W Central plaque component of spindle pole body (SPB) physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 2 2 2 Biochemical Activity, Proximity Label-MS
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
ADY3 YDL239C Protein required for spore wall formation physical 2 1 2 Two-hybrid, Two-hybrid
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
MPC54 YOR177C Component of the meiotic outer plaque physical 2 2 1 Two-hybrid, Affinity Capture-Western
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body physical 2 1 1 Two-hybrid, Two-hybrid
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SWI6 YLR182W Transcription cofactor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DMA2 YNL116W Ubiquitin-protein ligase (E3) regulation 1 1 1 qualitative western immunoblotting evidence
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Dosage Rescue
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
DYN1 YKR054C Cytoplasmic heavy chain dynein genetic 1 1 1 Synthetic Growth Defect
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein physical 1 1 1 Two-hybrid
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Synthetic Rescue
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex physical 1 1 1 Affinity Capture-MS
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 PCA
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Phenotypic Enhancement
SPO12 YHR152W Nucleolar protein of unknown function genetic 1 1 1 Dosage Rescue
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Dosage Rescue
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Lethality
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Phenotypic Enhancement
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Dosage Rescue
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Dosage Rescue
DMA2 YNL116W Ubiquitin-protein ligase (E3) physical 1 1 1 Affinity Capture-Western
DMA2 YNL116W Ubiquitin-protein ligase (E3) genetic 1 1 1 Synthetic Lethality
BUB2 YMR055C Mitotic exit network regulator genetic 1 1 1 Synthetic Growth Defect
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Dosage Rescue
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Proximity Label-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
MPS1 YDL028C Dual-specificity kinase physical 1 1 1 Affinity Capture-MS
CNM67 YNL225C Component of the spindle pole body outer plaque genetic 1 1 1 Synthetic Rescue
ADY4 YLR227C Structural component of the meiotic outer plaque physical 1 1 1 Two-hybrid
KIN4 YOR233W Serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
CLB4 YLR210W B-type cyclin involved in cell cycle progression genetic 1 1 1 Phenotypic Enhancement
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS