Standard name Systematic name Name description Description
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity Mitochondrial peroxiredoxin with thioredoxin peroxidase activity; has a role in reduction of hydroperoxides; reactivation requires Trr2p and glutathione; induced during respiratory growth and oxidative stress; phosphorylated; protein abundance increases in response to DNA replication stress
Visualize the interactome of PRX1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 158

CYCLoPs localization & abundance

WT1 WT2 WT3
Endosome 0.073 NaN 0.079
Mito 0.906 0.969 0.729
Vac/Vac Memb 0.178 0.109 0.086
Cell Periphery NaN 0.117 NaN
Golgi NaN NaN 0.236
Peroxisome NaN NaN 0.093

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 4510

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PRX1 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0551 (hydrogen peroxide reductase (thioredoxin))

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity physical 4 2 3 Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DER1 YBR201W ER membrane protein that promotes export of misfolded polypeptides genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SRX1 YKL086W Sulfiredoxin physical 2 2 2 Reconstituted Complex, PCA
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 2 1 2 Negative Genetic, Negative Genetic
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 2 1 2 Negative Genetic, Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 2 1 2 Negative Genetic, Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
PXP1 YEL020C Peroxisomal matrix protein genetic 2 1 2 Negative Genetic, Negative Genetic
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
AHP1 YLR109W Thiol-specific peroxiredoxin genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GYP6 YJL044C GTPase-activating protein (GAP) for yeast Rab family member Ypt6p genetic 2 1 1 Negative Genetic, Negative Genetic
CAF4 YKR036C WD40 repeat-containing protein associated with the CCR4-NOT complex genetic 2 1 1 Negative Genetic, Negative Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 2 1 1 Negative Genetic, Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
MED2 YDL005C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 DNA to cDNA expression microarray evidence
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family regulation 1 1 1 RNA-sequencing evidence
SIR3 YLR442C Silencing protein regulation 1 1 1 RNA-sequencing evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains regulation 1 1 1 RNA-sequencing evidence
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes regulation 1 1 1 DNA to cDNA expression microarray evidence
PUT3 YKL015W Transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Biochemical Activity
MAS1 YLR163C Beta subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Negative Genetic
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL4 YLR439W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
DOA4 YDR069C Ubiquitin hydrolase physical 1 1 1 Affinity Capture-MS
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) physical 1 1 1 Affinity Capture-RNA
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
MDH1 YKL085W Mitochondrial malate dehydrogenase physical 1 1 1 Affinity Capture-MS
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 1 1 1 Negative Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein physical 1 1 1 Affinity Capture-MS
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Negative Genetic
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase genetic 1 1 1 Phenotypic Enhancement
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
GDH2 YDL215C NAD(+)-dependent glutamate dehydrogenase genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease physical 1 1 1 Biochemical Activity
GLR1 YPL091W Cytosolic and mitochondrial glutathione oxidoreductase genetic 1 1 1 Phenotypic Suppression
HUL4 YJR036C Protein with similarity to hect domain E3 ubiquitin-protein ligases genetic 1 1 1 Negative Genetic
HYR1 YIR037W Glutathione peroxidase genetic 1 1 1 Synthetic Growth Defect
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
COQ8 YGL119W ATPase required for ubiquinone biosynthesis and respiratory growth physical 1 1 1 Affinity Capture-MS
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway physical 1 1 1 Affinity Capture-MS
TRX3 YCR083W Mitochondrial thioredoxin physical 1 1 1 Affinity Capture-Western
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
YFH1 YDL120W Mitochondrial matrix iron chaperone genetic 1 1 1 Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Synthetic Growth Defect
TSA2 YDR453C Stress inducible cytoplasmic thioredoxin peroxidase genetic 1 1 1 Synthetic Growth Defect
TRR2 YHR106W Mitochondrial thioredoxin reductase genetic 1 1 1 Phenotypic Suppression
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
TMH11 YJR085C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Positive Genetic
GPX2 YBR244W Phospholipid hydroperoxide glutathione peroxidase genetic 1 1 1 Synthetic Growth Defect
ERP4 YOR016C Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
GPX1 YKL026C Phospholipid hydroperoxide glutathione peroxidase genetic 1 1 1 Synthetic Growth Defect
GRX2 YDR513W Cytoplasmic glutaredoxin genetic 1 1 1 Phenotypic Enhancement
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS