TRP1 |
YDR007W |
Phosphoribosylanthranilate isomerase |
genetic |
5 |
4 |
5 |
Dosage Rescue, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
3 |
3 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
physical |
2 |
2 |
2 |
Affinity Capture-MS, PCA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
TKL1 |
YPR074C |
Transketolase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
2 |
1 |
1 |
Dosage Rescue, Dosage Rescue |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
regulation |
1 |
1 |
1 |
quantitative reverse transcription polymerase chain reaction evidence |
NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
KAP123 |
YER110C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
physical |
1 |
1 |
1 |
Two-hybrid |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN9 |
YDR427W |
Non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
EMP24 |
YGL200C |
Component of the p24 complex |
physical |
1 |
1 |
1 |
PCA |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
1 |
1 |
1 |
Co-localization |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP42 |
YDR171W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Dosage Rescue |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
physical |
1 |
1 |
1 |
Two-hybrid |
LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
physical |
1 |
1 |
1 |
Two-hybrid |
PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSC13 |
YDL015C |
Enoyl reductase |
physical |
1 |
1 |
1 |
PCA |
YET1 |
YKL065C |
Endoplasmic reticulum transmembrane protein |
physical |
1 |
1 |
1 |
PCA |
YDL199C |
YDL199C |
Putative transporter |
physical |
1 |
1 |
1 |
PCA |
TAT1 |
YBR069C |
Amino acid transporter for valine, leucine, isoleucine, and tyrosine |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
THR1 |
YHR025W |
Homoserine kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
YPT31 |
YER031C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA64 |
YDR117C |
Protein of unknown function that associates with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
XPT1 |
YJR133W |
Xanthine-guanine phosphoribosyl transferase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSZ1 |
YHR064C |
Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ABP1 |
YCR088W |
Actin-binding protein of the cortical actin cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
physical |
1 |
1 |
1 |
PCA |
CYC8 |
YBR112C |
General transcriptional co-repressor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
HYM1 |
YKL189W |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Dosage Rescue |
LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
physical |
1 |
1 |
1 |
PCA |
CWC24 |
YLR323C |
General splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PRM9 |
YAR031W |
Pheromone-regulated protein |
physical |
1 |
1 |
1 |
PCA |
ERC1 |
YHR032W |
Member of the multi-drug and toxin extrusion (MATE) family |
genetic |
1 |
1 |
1 |
Dosage Rescue |
MST27 |
YGL051W |
Putative integral membrane protein, involved in vesicle formation |
physical |
1 |
1 |
1 |
PCA |
AMD1 |
YML035C |
AMP deaminase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
physical |
1 |
1 |
1 |
PCA |
ELO3 |
YLR372W |
Elongase |
physical |
1 |
1 |
1 |
PCA |
HIP1 |
YGR191W |
High-affinity histidine permease |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BNR1 |
YIL159W |
Formin |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
physical |
1 |
1 |
1 |
PCA |
STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP51 |
YIL002C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC1 |
YJR010C-A |
Subunit of the signal peptidase complex (SPC) |
physical |
1 |
1 |
1 |
PCA |
RIM4 |
YHL024W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERP5 |
YHR110W |
Protein with similarity to Emp24p and Erv25p |
physical |
1 |
1 |
1 |
PCA |
ATG21 |
YPL100W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGE1 |
YPR198W |
Plasma membrane multidrug transporter |
physical |
1 |
1 |
1 |
PCA |
BAP2 |
YBR068C |
High-affinity leucine permease |
genetic |
1 |
1 |
1 |
Dosage Rescue |
ERP4 |
YOR016C |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
PCA |
ARO7 |
YPR060C |
Chorismate mutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HPT1 |
YDR399W |
Dimeric hypoxanthine-guanine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CHO1 |
YER026C |
Phosphatidylserine synthase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
APT2 |
YDR441C |
Potential adenine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
GAS2 |
YLR343W |
1,3-beta-glucanosyltransferase |
physical |
1 |
1 |
1 |
PCA |
SCS3 |
YGL126W |
Protein required for normal ER membrane biosynthesis in response to ER |
physical |
1 |
1 |
1 |
PCA |