UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
physical |
17 |
4 |
9 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Protein-peptide, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
UTP18 |
YJL069C |
Small-subunit processome protein involved in pre-18S rRNA maturation |
physical |
12 |
2 |
10 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS |
PWP2 |
YCR057C |
Conserved 90S pre-ribosomal component |
physical |
12 |
2 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
NOC4 |
YPR144C |
Nucleolar protein |
physical |
8 |
3 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid |
MPP10 |
YJR002W |
Component of the SSU processome and 90S preribosome |
physical |
7 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western |
UTP22 |
YGR090W |
Component of the small-subunit processome |
physical |
7 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid |
UTP13 |
YLR222C |
Nucleolar protein |
physical |
6 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS |
ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid |
DIP2 |
YLR129W |
Nucleolar protein |
physical |
5 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
UTP10 |
YJL109C |
Nucleolar protein |
physical |
5 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
UTP7 |
YER082C |
Nucleolar protein |
physical |
5 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SAS10 |
YDL153C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
5 |
2 |
2 |
Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western |
UTP6 |
YDR449C |
Nucleolar protein |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid |
NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RRP9 |
YPR137W |
Protein involved in pre-rRNA processing |
physical |
4 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
UTP9 |
YHR196W |
Nucleolar protein |
physical |
4 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-MS |
UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
UTP14 |
YML093W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Co-purification |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
2 |
1 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
ENP2 |
YGR145W |
Component of the SSU |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NAN1 |
YPL126W |
U3 snoRNP protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
UTP15 |
YMR093W |
Nucleolar protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
EMG1 |
YLR186W |
Methyltransferase for rRNA |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
KRE33 |
YNL132W |
Acetyltransferase required for biogenesis of small ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
UTP20 |
YBL004W |
Component of the small-subunit (SSU) processome |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IMP3 |
YHR148W |
Component of the SSU processome |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ROK1 |
YGL171W |
RNA-dependent ATPase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
UTP13 |
YLR222C |
Nucleolar protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
UTP9 |
YHR196W |
Nucleolar protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YJR120W |
YJR120W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DIM1 |
YPL266W |
Essential 18S rRNA dimethylase (dimethyladenosine transferase) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SGD1 |
YLR336C |
Essential nuclear protein |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Two-hybrid |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP9 |
YJL010C |
Essential subunit of U3-containing 90S preribosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP9 |
YJL010C |
Essential subunit of U3-containing 90S preribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP5 |
YAL033W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRE29 |
YER038C |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIP2 |
YLR129W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP18 |
YJL069C |
Small-subunit processome protein involved in pre-18S rRNA maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR4 |
YJL050W |
RNA duplex-sensing translocase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MTR4 |
YJL050W |
RNA duplex-sensing translocase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP9 |
YPR137W |
Protein involved in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIS3 |
YOL021C |
Exosome core complex catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP4 |
YHR069C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC4 |
YKR008W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUD1 |
YBR119W |
U1 snRNP A protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Positive Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCL1 |
YOL010W |
Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CYR1 |
YJL005W |
Adenylate cyclase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPP10 |
YJR002W |
Component of the SSU processome and 90S preribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP7 |
YER082C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPP1 |
YGR198W |
Cargo-transport protein involved in endocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDL177C |
YDL177C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL140C |
YNL140C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCL068C |
YCL068C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER189W |
YER189W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR213W-B |
YHR213W-B |
Pseudogenic fragment with similarity to flocculins |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL245W |
YPL245W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMP4 |
YNL075W |
Component of the SSU processome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP14 |
YDL148C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Two-hybrid |
NOP14 |
YDL148C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESF2 |
YNR054C |
Essential nucleolar protein involved in pre-18S rRNA processing |
physical |
1 |
1 |
1 |
Two-hybrid |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAF1 |
YDR005C |
Highly conserved negative regulator of RNA polymerase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR3 |
YGR158C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIF5 |
YPR041W |
Translation initiation factor eIF5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
physical |
1 |
1 |
1 |
Two-hybrid |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMS1 |
YLR003C |
Putative subunit of the 90S preribosome processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
physical |
1 |
1 |
1 |
Proximity Label-MS |
GSP1 |
YLR293C |
Ran GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPZ2 |
YDR436W |
Serine/threonine protein phosphatase Z, isoform of Ppz1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP14 |
YML093W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
physical |
1 |
1 |
1 |
Two-hybrid |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
PXR1 |
YGR280C |
Essential protein involved in rRNA and snoRNA maturation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
physical |
1 |
1 |
1 |
Proximity Label-MS |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
physical |
1 |
1 |
1 |
Proximity Label-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
physical |
1 |
1 |
1 |
Proximity Label-MS |
RRP3 |
YHR065C |
Protein involved in rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS8B |
YER102W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCD1 |
YHR144C |
Deoxycytidine monophosphate (dCMP) deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO5 |
YMR109W |
One of two type I myosin motors |
genetic |
1 |
1 |
1 |
Negative Genetic |
STN1 |
YDR082W |
Telomere end-binding and capping protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSA3 |
YBL075C |
ATPase involved in protein folding and the response to stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HFA1 |
YMR207C |
Mitochondrial acetyl-coenzyme A carboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSV2 |
YGR223C |
Phosphatidylinositol 3,5-bisphosphate-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC3 |
YAL001C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC3 |
YAL001C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAF1 |
YIL019W |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL7A |
YGL076C |
Ribosomal 60S subunit protein L7A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HBS1 |
YKR084C |
GTPase with similarity to translation release factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AUA1 |
YFL010W-A |
Protein required for the negative regulation by ammonia of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAT2 |
YMR136W |
Protein containing GATA family zinc finger motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP14 |
YLR295C |
Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCF2 |
YLR051C |
Nucleolar protein involved in the early steps of 35S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICL1 |
YER065C |
Isocitrate lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET10 |
YFR030W |
Subunit alpha of assimilatory sulfite reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPP6 |
YNR024W |
Nuclear exosome-associated RNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
NDT80 |
YHR124W |
Meiosis-specific transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAS10 |
YDL153C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP36 |
YOR287C |
Component of 90S preribosomes |
physical |
1 |
1 |
1 |
Two-hybrid |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SQS1 |
YNL224C |
Protein that stimulates the ATPase and helicase activities of Prp43p |
physical |
1 |
1 |
1 |
Two-hybrid |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM38 |
YOL027C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LIP1 |
YMR298W |
Ceramide synthase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRT14 |
YIL127C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSI2 |
YOL007C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DLD1 |
YDL174C |
Major mitochondrial D-lactate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC60 |
YKR016W |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FYV7 |
YLR068W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AGC1 |
YPR021C |
Mitochondrial amino acid transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FLX1 |
YIL134W |
Mitochondrial flavin adenine dinucleotide transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIO4 |
YNR057C |
Dethiobiotin synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BCD1 |
YHR040W |
Essential protein required for the accumulation of box C/D snoRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP30 |
YKR060W |
Subunit of U3-containing 90S preribosome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRF5 |
YNL299W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PZF1 |
YPR186C |
Transcription factor IIIA (TFIIIA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDL1 |
YIL167W |
Blocked reading frame otherwise encoding L-serine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRT15 |
YLR162W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPT1 |
YOL102C |
tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |