| FKH1 | YIL131C | Forkhead family transcription factor | regulation | 3 | 2 | 3 | chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments | 
            
                | MEK1 | YOR351C | Meiosis-specific serine/threonine protein kinase | genetic | 3 | 1 | 3 | Negative Genetic, Negative Genetic, Negative Genetic | 
            
                | SPT10 | YJL127C | Histone H3 acetylase with a role in transcriptional regulation | regulation | 2 | 1 | 2 | DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence | 
            
                | VAC14 | YLR386W | Enzyme regulator | genetic | 2 | 1 | 2 | Positive Genetic, Positive Genetic | 
            
                | GLC7 | YER133W | Type 1 S/T protein phosphatase (PP1) catalytic subunit | genetic | 2 | 1 | 1 | Synthetic Growth Defect, Synthetic Growth Defect | 
            
                | FKH2 | YNL068C | Forkhead family transcription factor | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | RAP1 | YNL216W | Essential DNA-binding transcription regulator that binds many loci | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | YAP5 | YIR018W | Basic leucine zipper (bZIP) iron-sensing transcription factor | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | FHL1 | YPR104C | Regulator of ribosomal protein (RP) transcription | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence | 
            
                | UME6 | YDR207C | Rpd3L histone deacetylase complex subunit | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence | 
            
                | SIN3 | YOL004W | Component of both the Rpd3S and Rpd3L histone deacetylase complexes | regulation | 1 | 1 | 1 | DNA to cDNA expression microarray evidence | 
            
                | CKA1 | YIL035C | Alpha catalytic subunit of casein kinase 2 (CK2) | physical | 1 | 1 | 1 | Affinity Capture-MS | 
            
                | RPA49 | YNL248C | RNA polymerase I subunit A49 | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RRP8 | YDR083W | Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ACT1 | YFL039C | Actin, structural protein in cytoskeleton | genetic | 1 | 1 | 1 | Synthetic Haploinsufficiency | 
            
                | CCR4 | YAL021C | Component of the CCR4-NOT transcriptional complex | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | ARP3 | YJR065C | Essential component of the Arp2/3 complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | CDC11 | YJR076C | Component of the septin ring that is required for cytokinesis | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | BUD31 | YCR063W | Component of the SF3b subcomplex of the U2 snRNP | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | DCP2 | YNL118C | Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | DHH1 | YDL160C | Cytoplasmic DEAD-box helicase and mRNA decapping activator | physical | 1 | 1 | 1 | Affinity Capture-RNA | 
            
                | HSC82 | YMR186W | Cytoplasmic chaperone of the Hsp90 family | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | HSP82 | YPL240C | Hsp90 chaperone | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | ILV1 | YER086W | Threonine deaminase, catalyzes first step in isoleucine biosynthesis | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | OPI1 | YHL020C | Transcriptional regulator of a variety of genes | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | BZZ1 | YHR114W | SH3 domain protein implicated in regulating actin polymerization | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | SLA1 | YBL007C | Cytoskeletal protein binding protein | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | LSB3 | YFR024C-A | Protein containing a C-terminal SH3 domain | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | SNF5 | YBR289W | Subunit of the SWI/SNF chromatin remodeling complex | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | SGF29 | YCL010C | Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | PTC1 | YDL006W | Type 2C protein phosphatase (PP2C) | genetic | 1 | 1 | 1 | Dosage Rescue | 
            
                | SWD1 | YAR003W | Subunit of the COMPASS (Set1C) complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | RIO2 | YNL207W | Essential serine kinase involved in the processing of 20S pre-rRNA | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | HYP2 | YEL034W | Translation elongation factor eIF-5A | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | GSF2 | YML048W | Endoplasmic reticulum (ER) localized integral membrane protein | physical | 1 | 1 | 1 | PCA | 
            
                | PMA1 | YGL008C | Plasma membrane P2-type H+-ATPase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | APM3 | YBR288C | Mu3-like subunit of the clathrin associated protein complex (AP-3) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ELM1 | YKL048C | Serine/threonine protein kinase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | NBP2 | YDR162C | Protein involved in the HOG (high osmolarity glycerol) pathway | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | PEX29 | YDR479C | ER-resident protein involved in peroxisomal biogenesis | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | MOB2 | YFL034C-B | Activator of Cbk1p kinase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | VAM7 | YGL212W | Vacuolar SNARE protein | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | BUR6 | YER159C | Subunit of a heterodimeric NC2 transcription regulator complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ELO3 | YLR372W | Elongase | physical | 1 | 1 | 1 | PCA | 
            
                | STU1 | YBL034C | Microtubule plus-end-tracking non-motor protein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | JNM1 | YMR294W | Component of the yeast dynactin complex | genetic | 1 | 1 | 1 | Synthetic Lethality | 
            
                | SNL1 | YIL016W | Ribosome-associated protein | physical | 1 | 1 | 1 | PCA | 
            
                | SEC2 | YNL272C | Guanyl-nucleotide exchange factor for the small G-protein Sec4p | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | MCM7 | YBR202W | Component of the Mcm2-7 hexameric helicase complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | GTT1 | YIR038C | ER associated glutathione S-transferase | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | TAO3 | YIL129C | Component of the RAM signaling network | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | DPM1 | YPR183W | Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | HMG1 | YML075C | HMG-CoA reductase | physical | 1 | 1 | 1 | PCA | 
            
                | VMA21 | YGR105W | Integral membrane protein required for V-ATPase function | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | GPI2 | YPL076W | Protein involved in the synthesis of GlcNAc-PI | physical | 1 | 1 | 1 | PCA | 
            
                | CUE1 | YMR264W | Ubiquitin-binding protein | physical | 1 | 1 | 1 | PCA | 
            
                | IFA38 | YBR159W | Microsomal beta-keto-reductase | physical | 1 | 1 | 1 | PCA | 
            
                | HTD2 | YHR067W | Mitochondrial 3-hydroxyacyl-thioester dehydratase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | CWP2 | YKL096W-A | Covalently linked cell wall mannoprotein | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SEC14 | YMR079W | Phosphatidylinositol/phosphatidylcholine transfer protein | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | GLN4 | YOR168W | Glutamine tRNA synthetase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SPB4 | YFL002C | Putative ATP-dependent RNA helicase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SAD1 | YFR005C | Conserved zinc-finger domain protein involved in pre-mRNA splicing | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | SND3 | YBR106W | Involved in SRP-independent protein targeting to the ER | physical | 1 | 1 | 1 | PCA | 
            
                | ERP4 | YOR016C | Member of the p24 family involved in ER to Golgi transport | physical | 1 | 1 | 1 | PCA | 
            
                | VOA1 | YGR106C | ER protein that functions in assembly of the V0 sector of V-ATPase | genetic | 1 | 1 | 1 | Synthetic Growth Defect | 
            
                | ERG3 | YLR056W | C-5 sterol desaturase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | UIP3 | YAR027W | Putative integral membrane protein of unknown function | physical | 1 | 1 | 1 | Two-hybrid | 
            
                | SLM4 | YBR077C | Subunit of the EGO/GSE complex | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | STE24 | YJR117W | Highly conserved zinc metalloprotease | physical | 1 | 1 | 1 | PCA | 
            
                | ERG9 | YHR190W | Farnesyl-diphosphate farnesyl transferase (squalene synthase) | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | ERD1 | YDR414C | Predicted membrane protein required for lumenal ER protein retention | physical | 1 | 1 | 1 | PCA | 
            
                | MRX14 | YDR115W | Putative mitochondrial ribosomal protein of the large subunit | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | CRD1 | YDL142C | Cardiolipin synthase | genetic | 1 | 1 | 1 | Synthetic Lethality | 
            
                | MDL2 | YPL270W | Mitochondrial inner membrane half-type ABC transporter | physical | 1 | 1 | 1 | PCA | 
            
                | GPI8 | YDR331W | Catalytic subunit of the ER membrane GPI transamidase complex | physical | 1 | 1 | 1 | PCA | 
            
                | YAR028W | YAR028W | Putative integral membrane protein | physical | 1 | 1 | 1 | PCA | 
            
                | VRG4 | YGL225W | Golgi GDP-mannose transporter | physical | 1 | 1 | 1 | PCA | 
            
                | YET1 | YKL065C | Endoplasmic reticulum transmembrane protein | physical | 1 | 1 | 1 | PCA | 
            
                | YOP1 | YPR028W | Reticulon-interacting protein | physical | 1 | 1 | 1 | PCA | 
            
                | YOL029C | YOL029C | Putative protein of unknown function | genetic | 1 | 1 | 1 | Positive Genetic | 
            
                | YTM1 | YOR272W | Ribosomal assembly factor and 66S pre-ribosomal particle constituent | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | YJU2 | YKL095W | Essential protein required for pre-mRNA splicing | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | MRS3 | YJL133W | Iron transporter, mediates Fe2+ transport across inner mito membrane | physical | 1 | 1 | 1 | PCA | 
            
                | VAC7 | YNL054W | Integral vacuolar membrane protein | physical | 1 | 1 | 1 | PCA | 
            
                | SPT14 | YPL175W | UDP-glycosyltransferase subunit of the GPI-GnT complex | physical | 1 | 1 | 1 | PCA | 
            
                | MMM1 | YLL006W | ER integral membrane protein, ERMES complex subunit | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | OAR1 | YKL055C | Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase | genetic | 1 | 1 | 1 | Negative Genetic | 
            
                | TAD3 | YLR316C | Subunit of tRNA-specific adenosine-34 deaminase | genetic | 1 | 1 | 1 | Negative Genetic |