Standard name Systematic name Name description Description
WTM2 YOR229W Transcriptional modulator Transcriptional modulator; involved in regulation of meiosis, silencing, and expression of RNR genes; involved in response to replication stress; contains WD repeats; relocalizes to the cytosol in response to hypoxia; WTM2 has a paralog, UME1, that arose from the whole genome duplication
Visualize the interactome of WTM2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 168

CYCLoPs localization & abundance

WT1 WT2 WT3
Nuc Periphery 0.098 NaN NaN
Nucleus 0.951 0.956 0.960
Mito NaN NaN 0.099

GFP localization & abundance

GFP localization GFP abundance
nucleus 3750

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
WTM2 3 2 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
WTM1 YOR230W Transcriptional modulator physical 6 3 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid
WTM2 YOR229W Transcriptional modulator physical 5 3 4 Affinity Capture-Western, Two-hybrid, PCA, Two-hybrid, PCA
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit physical 4 3 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit physical 3 3 3 Affinity Capture-Western, Co-purification, Two-hybrid
YOR283W YOR283W Phosphatase with a broad substrate specificity physical 2 2 2 Affinity Capture-MS, Two-hybrid
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Positive Genetic, Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SUA7 YPR086W Transcription factor TFIIB regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN4 YKL062W Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex regulation 1 1 1 DNA to cDNA expression microarray evidence
SOL4 YGR248W 6-phosphogluconolactonase regulation 1 1 1 DNA to cDNA expression microarray evidence
YPK2 YMR104C AGC-type S/T protein kinase regulation 1 1 1 DNA to cDNA expression microarray evidence
ARG1 YOL058W Arginosuccinate synthetase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YGP1 YNL160W Cell wall-related secretory glycoprotein regulation 1 1 1 DNA to cDNA expression microarray evidence
CDA1 YLR307W Chitin deacetylase regulation 1 1 1 DNA to cDNA expression microarray evidence
ATG16 YMR159C Conserved protein involved in autophagy regulation 1 1 1 DNA to cDNA expression microarray evidence
CIP1 YPL014W Cyclin-dependent kinase inhibitor regulation 1 1 1 DNA to cDNA expression microarray evidence
HSP104 YLL026W Disaggregase regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR466C-B YLR466C-B Dubious open reading frame regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YJL022W YJL022W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR252W YLR252W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
YJR114W YJR114W Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
GLK1 YCL040W Glucokinase regulation 1 1 1 DNA to cDNA expression microarray evidence
GAD1 YMR250W Glutamate decarboxylase regulation 1 1 1 DNA to cDNA expression microarray evidence
GSY1 YFR015C Glycogen synthase regulation 1 1 1 DNA to cDNA expression microarray evidence
SPI1 YER150W GPI-anchored cell wall protein involved in weak acid resistance regulation 1 1 1 DNA to cDNA expression microarray evidence
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TSL1 YML100W Large subunit of trehalose 6-phosphate synthase/phosphatase complex regulation 1 1 1 DNA to cDNA expression microarray evidence
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LEU5 YHR002W Mitochondrial carrier protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AAC1 YMR056C Mitochondrial inner membrane ADP/ATP translocator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
MSS116 YDR194C Mitochondrial transcription elongation factor regulation 1 1 1 DNA to cDNA expression microarray evidence
HSP30 YCR021C Negative regulator of the H(+)-ATPase Pma1p regulation 1 1 1 DNA to cDNA expression microarray evidence
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex regulation 1 1 1 DNA to cDNA expression microarray evidence
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane regulation 1 1 1 DNA to cDNA expression microarray evidence
TPO4 YOR273C Polyamine transporter of the major facilitator superfamily regulation 1 1 1 DNA to cDNA expression microarray evidence
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily regulation 1 1 1 DNA to cDNA expression microarray evidence
STP4 YDL048C Protein containing a Kruppel-type zinc-finger domain regulation 1 1 1 DNA to cDNA expression microarray evidence
GAT2 YMR136W Protein containing GATA family zinc finger motifs regulation 1 1 1 DNA to cDNA expression microarray evidence
DCV1 YFR012W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR297W YLR297W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
AIM17 YHL021C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YRO2 YBR054W Protein with a putative role in response to acid stress regulation 1 1 1 DNA to cDNA expression microarray evidence
SPL2 YHR136C Protein with similarity to cyclin-dependent kinase inhibitors regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCV2 YMR189W P subunit of the mitochondrial glycine decarboxylase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YCL042W YCL042W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
FMP42 YMR221C Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NFT1 YKR103W Putative transporter of the MRP subfamily regulation 1 1 1 DNA to cDNA expression microarray evidence
RIE1 YGR250C RNA binding protein and negative regulator of START regulation 1 1 1 DNA to cDNA expression microarray evidence
SPR3 YGR059W Sporulation-specific homolog of the CDC3/10/11/12 family of genes regulation 1 1 1 DNA to cDNA expression microarray evidence
PRY2 YKR013W Sterol binding protein involved in the export of acetylated sterols regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress genetic 1 1 1 Positive Genetic
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Two-hybrid
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BUD14 YAR014C Protein involved in bud-site selection physical 1 1 1 Two-hybrid
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Two-hybrid
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Dosage Rescue
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Dosage Growth Defect
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Two-hybrid
HRK1 YOR267C Protein kinase genetic 1 1 1 Negative Genetic
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor genetic 1 1 1 Negative Genetic
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Positive Genetic
YRR1 YOR162C Zn2-Cys6 zinc-finger transcription factor genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Positive Genetic
YAR066W YAR066W Putative GPI protein genetic 1 1 1 Negative Genetic
YPR089W YPR089W Protein of unknown function genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta physical 1 1 1 Co-localization
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Two-hybrid
INA1 YLR413W Protein of unknown function genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Dosage Rescue
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Positive Genetic
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins genetic 1 1 1 Negative Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system genetic 1 1 1 Positive Genetic
TUL1 YKL034W Subunit of the DSC ubiquitin ligase complex genetic 1 1 1 Positive Genetic
SML1 YML058W Ribonucleotide reductase inhibitor genetic 1 1 1 Dosage Rescue
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Positive Genetic
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Negative Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Positive Genetic
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
RPL39 YJL189W Ribosomal 60S subunit protein L39 physical 1 1 1 Two-hybrid
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Positive Genetic
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase genetic 1 1 1 Dosage Growth Defect
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Negative Genetic
PUT1 YLR142W Proline oxidase genetic 1 1 1 Positive Genetic
TMH18 YPR098C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
ULS1 YOR191W Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic