Standard name Systematic name Name description Description
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase Phosphoribosylaminoimidazole carboxylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway; red pigment accumulates in mutant cells deprived of adenine
Visualize the interactome of ADE2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.995 0.989 0.979
Cell Periphery NaN NaN 0.060

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 5410

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ADE2 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0911 (phosphoribosylaminoimidazole-carboxylase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
HPT1 YDR399W Dimeric hypoxanthine-guanine phosphoribosyltransferase genetic 6 2 4 Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ADE13 YLR359W Adenylosuccinate lyase genetic 3 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
FCY2 YER056C Purine-cytosine permease genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 2 2 Affinity Capture-Western, Co-purification
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
BAS1 YKR099W Myb-related transcription factor regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
HSP82 YPL240C Hsp90 chaperone genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase physical 1 1 1 Two-hybrid
RAD18 YCR066W E3 ubiquitin ligase physical 1 1 1 Two-hybrid
SED4 YCR067C Integral ER membrane protein that stimulates Sar1p GTPase activity physical 1 1 1 Two-hybrid
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 1 1 1 Affinity Capture-MS
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex physical 1 1 1 Two-hybrid
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
LYS5 YGL154C Phosphopantetheinyl transferase involved in lysine biosynthesis physical 1 1 1 Two-hybrid
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes physical 1 1 1 Two-hybrid
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 1 1 1 Two-hybrid
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 1 1 1 Synthetic Rescue
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p physical 1 1 1 PCA
PXA2 YKL188C Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p physical 1 1 1 PCA
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 1 1 1 PCA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Synthetic Rescue
ADE8 YDR408C Phosphoribosyl-glycinamide transformylase genetic 1 1 1 Phenotypic Suppression
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase genetic 1 1 1 Phenotypic Suppression
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway genetic 1 1 1 Phenotypic Suppression
ZUO1 YGR285C Ribosome-associated chaperone genetic 1 1 1 Synthetic Rescue
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) genetic 1 1 1 Synthetic Rescue
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone genetic 1 1 1 Synthetic Rescue
HAP1 YLR256W Zinc finger transcription factor genetic 1 1 1 Phenotypic Enhancement
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity genetic 1 1 1 Negative Genetic
GRE3 YHR104W Aldose reductase genetic 1 1 1 Negative Genetic
RPS24B YIL069C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
GRS2 YPR081C Glycine-tRNA synthetase, not expressed under normal growth conditions genetic 1 1 1 Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Positive Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Positive Genetic
NSA1 YGL111W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Positive Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Positive Genetic
GCD2 YGR083C Delta subunit of the translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Positive Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Positive Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Positive Genetic
ZTA1 YBR046C NADPH-dependent quinone reductase genetic 1 1 1 Positive Genetic
MIC12 YBR262C Component of the MICOS complex genetic 1 1 1 Positive Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Positive Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Positive Genetic
AQY3 YFL054C Putative channel-like protein genetic 1 1 1 Positive Genetic
CNN1 YFR046C Kinetochore protein genetic 1 1 1 Positive Genetic
YHI9 YHR029C Protein of unknown function genetic 1 1 1 Positive Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic
PRM2 YIL037C Pheromone-regulated protein genetic 1 1 1 Positive Genetic
VBA5 YKR105C Plasma membrane protein of the Major Facilitator Superfamily (MFS) genetic 1 1 1 Positive Genetic
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Positive Genetic
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Positive Genetic
PRP45 YAL032C Protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
TAF3 YPL011C TFIID subunit (47 kDa) genetic 1 1 1 Negative Genetic
TFB2 YPL122C Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
YDL124W YDL124W NADPH-dependent alpha-keto amide reductase genetic 1 1 1 Negative Genetic
YDL241W YDL241W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YFR006W YFR006W Putative X-Pro aminopeptidase genetic 1 1 1 Negative Genetic
FZF1 YGL254W Transcription factor involved in sulfite metabolism genetic 1 1 1 Negative Genetic
LNP1 YHR192W Lunapark family member involved in ER network formation genetic 1 1 1 Negative Genetic
MRPL8 YJL063C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MNS1 YJR131W Alpha-1,2-mannosidase genetic 1 1 1 Negative Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
MPD2 YOL088C Member of the protein disulfide isomerase (PDI) family genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Negative Genetic
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Synthetic Rescue
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic