Standard name Systematic name Name description Description
FBP1 YLR377C Fructose-1,6-bisphosphatase Fructose-1,6-bisphosphatase; key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism; undergoes either proteasome-mediated or autophagy-mediated degradation depending on growth conditions; glucose starvation results in redistribution to the periplasm; interacts with Vid30p
Visualize the interactome of FBP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data 589

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FBP1 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0449 (fructose-bisphosphatase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FBP1 YLR377C Fructose-1,6-bisphosphatase physical 3 2 3 Two-hybrid, Two-hybrid, Reconstituted Complex
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) physical 3 2 2 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
KOG1 YHR186C Subunit of TORC1 physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Co-fractionation
LST8 YNL006W Protein required for the transport of Gap1p physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Co-fractionation
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 2 2 Negative Genetic, Positive Genetic
SRP1 YNL189W Karyopherin alpha homolog physical 2 1 2 Two-hybrid, Two-hybrid
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
GPH1 YPR160W Glycogen phosphorylase required for the mobilization of glycogen genetic 2 1 2 Negative Genetic, Negative Genetic
SIP4 YJL089W C6 zinc cluster transcriptional activator regulation 2 2 1 chromatin immunoprecipitation-qPCR evidence, quantitative polymerase chain reaction evidence
TOG1 YER184C Transcriptional activator of oleate genes regulation 2 2 1 chromatin immunoprecipitation-PCR evidence, quantitative reverse transcription polymerase chain reaction evidence
CAT8 YMR280C Zinc cluster transcriptional activator regulation 2 2 1 chromatin immunoprecipitation-qPCR evidence, quantitative polymerase chain reaction evidence
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
FES1 YBR101C Hsp70 (Ssa1p) nucleotide exchange factor physical 2 1 1 Reconstituted Complex, Reconstituted Complex
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TUP1 YCR084C General repressor of transcription in complex with Cyc8p regulation 1 1 1 quantitative polymerase chain reaction evidence
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex regulation 1 1 1 quantitative polymerase chain reaction evidence
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III regulation 1 1 1 northern blot evidence
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 1 1 1 Affinity Capture-MS
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Affinity Capture-MS
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
ATP3 YBR039W Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ADK1 YDR226W Adenylate kinase, required for purine metabolism genetic 1 1 1 Negative Genetic
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 1 1 1 Negative Genetic
ALD5 YER073W Mitochondrial aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes physical 1 1 1 Affinity Capture-MS
ARP5 YNL059C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Positive Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Positive Genetic
MDH2 YOL126C Cytoplasmic malate dehydrogenase physical 1 1 1 Reconstituted Complex
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p physical 1 1 1 Affinity Capture-Western
MET17 YLR303W O-acetyl homoserine-O-acetyl serine sulfhydrylase physical 1 1 1 Affinity Capture-Western
YNR065C YNR065C Protein of unknown function physical 1 1 1 Affinity Capture-Western
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p physical 1 1 1 Affinity Capture-MS
PEX17 YNL214W Membrane peroxin of the peroxisomal importomer complex physical 1 1 1 Affinity Capture-Western
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins physical 1 1 1 Co-fractionation
KAP95 YLR347C Karyopherin beta physical 1 1 1 Two-hybrid
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Two-hybrid
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B physical 1 1 1 Two-hybrid
GSM1 YJL103C Putative zinc cluster protein of unknown function physical 1 1 1 Two-hybrid
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 1 1 1 Affinity Capture-Western
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase physical 1 1 1 Affinity Capture-MS
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Positive Genetic
PAL2 YHR097C Protein involved in clathrin-mediated endocytosis physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs physical 1 1 1 Affinity Capture-MS
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 1 1 1 Affinity Capture-MS
MDS3 YGL197W Putative component of the TOR regulatory pathway physical 1 1 1 Affinity Capture-MS
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Affinity Capture-MS
UBP14 YBR058C Ubiquitin-specific protease physical 1 1 1 Affinity Capture-MS
HSV2 YGR223C Phosphatidylinositol 3,5-bisphosphate-binding protein physical 1 1 1 Affinity Capture-MS
UBC8 YEL012W Ubiquitin-conjugating enzyme that regulates gluconeogenesis physical 1 1 1 Affinity Capture-Western
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 1 1 1 Affinity Capture-Western
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
VID24 YBR105C GID Complex regulatory subunit physical 1 1 1 Two-hybrid
GID10 YGR066C Recognition component (N-recognin) of the Pro/N-degron pathway physical 1 1 1 Affinity Capture-Western
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase genetic 1 1 1 Positive Genetic
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP genetic 1 1 1 Positive Genetic
THG1 YGR024C tRNAHis guanylyltransferase genetic 1 1 1 Positive Genetic
TRP4 YDR354W Anthranilate phosphoribosyl transferase genetic 1 1 1 Negative Genetic
FMS1 YMR020W Polyamine oxidase genetic 1 1 1 Positive Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
GAS4 YOL132W 1,3-beta-glucanosyltransferase genetic 1 1 1 Positive Genetic
PRS4 YBL068W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP genetic 1 1 1 Negative Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Negative Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Positive Genetic
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Positive Genetic
RMD9 YGL107C Mitochondrial protein that controls mitochondrial gene expression genetic 1 1 1 Positive Genetic
RSM19 YNR037C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Negative Genetic
YPL077C YPL077C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin genetic 1 1 1 Negative Genetic
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Positive Genetic
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Phenotypic Enhancement
HST4 YDR191W NAD(+)-dependent protein deacetylase genetic 1 1 1 Phenotypic Enhancement
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Phenotypic Enhancement
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
DYS1 YHR068W Deoxyhypusine synthase genetic 1 1 1 Positive Genetic
ATP17 YDR377W Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
CUZ1 YNL155W Protein with a role in the ubiquitin-proteasome pathway physical 1 1 1 Affinity Capture-MS
DAL2 YIR029W Allantoicase genetic 1 1 1 Negative Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Negative Genetic
AIM32 YML050W 2Fe-2S mitochondrial protein involved in redox quality control physical 1 1 1 Affinity Capture-MS