| ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
physical |
18 |
5 |
16 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Co-fractionation, Affinity Capture-MS, Co-purification, Reconstituted Complex, Affinity Capture-MS |
| RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
physical |
16 |
5 |
14 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Co-crystal Structure, Co-fractionation, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
12 |
7 |
9 |
Co-fractionation, Co-localization, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Co-purification, Reconstituted Complex, Affinity Capture-MS |
| TSR1 |
YDL060W |
Protein required for processing of 20S pre-rRNA in the cytoplasm |
physical |
7 |
4 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-MS |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
7 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
6 |
4 |
6 |
Co-localization, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS |
| NOB1 |
YOR056C |
Protein involved in proteasomal and 40S ribosomal subunit biogenesis |
physical |
6 |
4 |
6 |
Affinity Capture-MS, Reconstituted Complex, Co-fractionation, Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| DIM1 |
YPL266W |
Essential 18S rRNA dimethylase (dimethyladenosine transferase) |
physical |
6 |
4 |
5 |
Reconstituted Complex, Reconstituted Complex, Co-fractionation, Co-purification, Affinity Capture-MS, Co-purification |
| PNO1 |
YOR145C |
Essential nucleolar protein required for pre-18S rRNA processing |
physical |
4 |
3 |
4 |
Co-fractionation, Co-purification, Affinity Capture-MS, Co-purification |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
4 |
3 |
4 |
Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
3 |
3 |
Reconstituted Complex, Co-purification, Affinity Capture-MS |
| RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
2 |
3 |
Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
3 |
2 |
3 |
Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
3 |
2 |
3 |
Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
2 |
3 |
Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
2 |
3 |
Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
2 |
3 |
Co-purification, Affinity Capture-MS, Affinity Capture-MS |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
2 |
3 |
Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
3 |
2 |
2 |
Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
| RPS14B |
YJL191W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Reconstituted Complex, Affinity Capture-MS |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
| RPS21A |
YKR057W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
| RPS8B |
YER102W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
| RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
| RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
| RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
| RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
| RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Synthetic Lethality |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YRB2 |
YIL063C |
Protein of unknown function |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Synthetic Growth Defect |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Reconstituted Complex |
| ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CHA4 |
YLR098C |
DNA binding transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRX1 |
YOL077C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LOC1 |
YFR001W |
Nucleolar protein involved in the asymmetric localization of ASH1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIR2 |
YDR152W |
Highly-acidic RWD domain-containing cytoplasmic protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CSN9 |
YDR179C |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RRP12 |
YPL012W |
Protein required for export of the ribosomal subunits |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPS26A |
YGL189C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
| RLI1 |
YDR091C |
Essential Fe-S protein |
physical |
1 |
1 |
1 |
Co-purification |
| RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
| RPS23B |
YPR132W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
| RPS24B |
YIL069C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
| RPS30B |
YOR182C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
| RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
| RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Co-purification |
| RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS5 |
YJR123W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBS1 |
YBR165W |
Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM10 |
YOL093W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYC1 |
YOR179C |
Subunit of the APT subcomplex of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIT1 |
YMR283C |
Initiator methionine 2'-O-ribosyl phosphate transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME2 |
YMR302C |
Integral inner mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP157 |
YER105C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS18 |
YPR134W |
Nuclear encoded protein needed for splicing of mitochondrial intron |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NMD4 |
YLR363C |
Protein that may be involved in nonsense-mediated mRNA decay |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRP8 |
YDR083W |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YGR054W |
YGR054W |
Eukaryotic initiation factor eIF2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NMD5 |
YJR132W |
Karyopherin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPB1 |
YCL054W |
AdoMet-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YCR087C-A |
YCR087C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PML1 |
YLR016C |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MEF1 |
YLR069C |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSR2 |
YLR435W |
Protein with a potential role in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SXM1 |
YDR395W |
Nuclear transport factor (karyopherin) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PUF6 |
YDR496C |
Pumilio-homology domain protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POP8 |
YBL018C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRM7 |
YBR061C |
2'-O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YGR126W |
YGR126W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TMA23 |
YMR269W |
Nucleolar protein implicated in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PIH1 |
YHR034C |
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP16 |
YER002W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRM1 |
YOR201C |
Ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUV3 |
YPL029W |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RPS31 |
YLR167W |
Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| YPC1 |
YBR183W |
Alkaline ceramidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSP1 |
YLR293C |
Ran GTPase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP104 |
YLL026W |
Disaggregase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| JSN1 |
YJR091C |
Member of the Puf family of RNA-binding proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTL1 |
YMR180C |
RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ITT1 |
YML068W |
Protein that modulates the efficiency of translation termination |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BMT5 |
YIL096C |
Methyltransferase required for m3U2634 methylation of the 25S rRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAP120 |
YPL125W |
Karyopherin responsible for the nuclear import of Rpf1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EFT1 |
YOR133W |
Elongation factor 2 (EF-2), also encoded by EFT2 |
physical |
1 |
1 |
1 |
Co-fractionation |
| BUD23 |
YCR047C |
Ribosome biogenesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| EDC2 |
YER035W |
RNA-binding protein that directly activates mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBT1 |
YKL208W |
Protein involved in 5' RNA end processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
| APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |