Standard name Systematic name Name description Description
NUP1 YOR098C FG-nucleoporin component of central core of the nuclear pore complex FG-nucleoporin component of central core of the nuclear pore complex; contributes directly to nucleocytoplasmic transport and maintenance of thenuclear pore complex (NPC) permeability barrier; possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; both NUP1 and NUP60 are homologous to human NUP153
Visualize the interactome of NUP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.057 0.184 0.095
Nuc Periphery 0.736 0.807 0.786
Nucleolus 0.100 0.123 0.191
Nucleus 0.054 NaN NaN
Vac/Vac Memb 0.379 0.211 0.164
Cytoplasm NaN NaN 0.065

GFP localization & abundance

GFP localization GFP abundance
nuclear periphery 468

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NUP1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
KAP95 YLR347C Karyopherin beta physical 22 6 21 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, PCA, Co-crystal Structure, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
SRP1 YNL189W Karyopherin alpha homolog physical 14 3 12 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 5 3 4 Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 4 4 4 Two-hybrid, FRET, Reconstituted Complex, Affinity Capture-Western
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
KAP123 YER110C Karyopherin beta physical 3 3 3 Two-hybrid, Affinity Capture-Western, Reconstituted Complex
SAC3 YDR159W mRNA export factor physical 3 3 3 Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) physical 3 2 3 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 3 2 3 Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) physical 3 2 2 FRET, FRET, Affinity Capture-MS
MTR10 YOR160W Nuclear import receptor physical 2 2 2 Affinity Capture-Western, Two-hybrid
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 2 2 2 Co-fractionation, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 2 2 2 Synthetic Growth Defect, Synthetic Lethality
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex genetic 2 2 2 Synthetic Rescue, Synthetic Lethality
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 2 1 2 Reconstituted Complex, Reconstituted Complex
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SRP1 YNL189W Karyopherin alpha homolog genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MTR2 YKL186C mRNA transport regulator physical 2 1 2 Reconstituted Complex, Reconstituted Complex
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAD53 YPL153C DNA damage response kinase regulation 1 1 1 protein kinase assay evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 physical 1 1 1 Two-hybrid
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Synthetic Lethality
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly physical 1 1 1 Reconstituted Complex
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Two-hybrid
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 Affinity Capture-MS
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Synthetic Rescue
KAP114 YGL241W Karyopherin, responsible for nuclear import of specific proteins physical 1 1 1 Reconstituted Complex
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Lethality
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
NUD1 YOR373W Mitotic exit network (MEN) scaffold protein genetic 1 1 1 Synthetic Lethality
GPM1 YKL152C Tetrameric phosphoglycerate mutase physical 1 1 1 Affinity Capture-MS
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
NMD5 YJR132W Karyopherin physical 1 1 1 Affinity Capture-Western
BUB2 YMR055C Mitotic exit network regulator genetic 1 1 1 Synthetic Lethality
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein physical 1 1 1 Affinity Capture-MS
BFA1 YJR053W Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p genetic 1 1 1 Synthetic Lethality
KAP122 YGL016W Karyopherin beta physical 1 1 1 Affinity Capture-Western
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 1 1 1 Synthetic Lethality
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Biochemical Activity
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Dosage Growth Defect
SXM1 YDR395W Nuclear transport factor (karyopherin) physical 1 1 1 Affinity Capture-Western
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Co-purification
PCT1 YGR202C Cholinephosphate cytidylyltransferase physical 1 1 1 Affinity Capture-MS
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex physical 1 1 1 Affinity Capture-MS
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 Affinity Capture-MS
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Biochemical Activity
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Rescue
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Protein-RNA
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP157 YER105C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex physical 1 1 1 Affinity Capture-MS
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes physical 1 1 1 Affinity Capture-MS
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes physical 1 1 1 Reconstituted Complex
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
RPH1 YER169W JmjC domain-containing histone demethylase physical 1 1 1 Affinity Capture-Western
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-Western
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-Western
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Rescue
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Synthetic Lethality
YRB1 YDR002W Ran GTPase binding protein genetic 1 1 1 Synthetic Lethality
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Phenotypic Suppression
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Rescue
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
RPL11A YPR102C Ribosomal 60S subunit protein L11A genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Dosage Rescue
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MSN5 YDR335W Karyopherin physical 1 1 1 FRET
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge physical 1 1 1 Reconstituted Complex
ATG8 YBL078C Ub-like protein physical 1 1 1 Affinity Capture-MS
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 1 1 1 Dosage Growth Defect
KAR2 YJL034W ATPase involved in protein import into the ER physical 1 1 1 Affinity Capture-Western
AVT1 YJR001W Vacuolar transporter physical 1 1 1 PCA
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Dosage Rescue
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER genetic 1 1 1 Synthetic Rescue
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Dosage Lethality