Standard name Systematic name Name description Description
PHO81 YGR233C Cyclin-dependent kinase (CDK) inhibitor Cyclin-dependent kinase (CDK) inhibitor; regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p; relative distribution to the nucleus increases upon DNA replication stress
Visualize the interactome of PHO81
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.118 0.145 0.178
Nucleus 0.634 0.581 0.515
Vac/Vac Memb 0.274 0.161 0.079
Mito NaN 0.371 0.401

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 2930

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PHO81 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PHO85 YPL031C Cyclin-dependent kinase physical 15 5 12 Affinity Capture-MS, Two-hybrid, Two-hybrid, Biochemical Activity, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Reconstituted Complex, Two-hybrid, Biochemical Activity, Affinity Capture-MS, Biochemical Activity
PHO80 YOL001W Cyclin physical 12 5 11 Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS
PHO80 YOL001W Cyclin genetic 3 2 3 Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
PCL7 YIL050W Pho85p cyclin of the Pho80p subfamily physical 3 2 2 Affinity Capture-Western, Two-hybrid, Affinity Capture-Western
CYR1 YJL005W Adenylate cyclase physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PHO84 YML123C High-affinity inorganic phosphate (Pi) transporter genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 2 1 2 Negative Genetic, Negative Genetic
ALK2 YBL009W Atypical protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
PLC1 YPL268W Phospholipase C genetic 2 2 1 Dosage Rescue, Phenotypic Enhancement
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
BRE1 YDL074C E3 ubiquitin ligase regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
LEO1 YOR123C Component of the Paf1 complex regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
CTR9 YOL145C Component of the Paf1p complex involved in transcription elongation physical 1 1 1 Two-hybrid
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Phenotypic Suppression
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex physical 1 1 1 Affinity Capture-MS
EMG1 YLR186W Methyltransferase for rRNA physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Negative Genetic
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Phenotypic Suppression
PHO85 YPL031C Cyclin-dependent kinase genetic 1 1 1 Phenotypic Suppression
SRV2 YNL138W CAP (cyclase-associated protein) physical 1 1 1 Affinity Capture-MS
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Two-hybrid
RRN7 YJL025W Component of the core factor (CF) rDNA transcription factor complex physical 1 1 1 Two-hybrid
TRM9 YML014W tRNA methyltransferase physical 1 1 1 Two-hybrid
YCF1 YDR135C Vacuolar glutathione S-conjugate transporter physical 1 1 1 PCA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 1 1 1 Phenotypic Enhancement
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Positive Genetic
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SED1 YDR077W Major stress-induced structural GPI-cell wall glycoprotein genetic 1 1 1 Negative Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
YDR524C-B YDR524C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
YNR068C YNR068C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR381W-A YOR381W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization physical 1 1 1 Affinity Capture-MS
ATG11 YPR049C Adapter protein for pexophagy and the Cvt targeting pathway physical 1 1 1 Two-hybrid
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
BUD32 YGR262C Protein kinase physical 1 1 1 Affinity Capture-MS
BUD32 YGR262C Protein kinase genetic 1 1 1 Dosage Growth Defect
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Rescue
MTQ2 YDR140W S-adenosylmethionine-dependent methyltransferase physical 1 1 1 Affinity Capture-MS
DDI1 YER143W Aspartic-type endopeptidase physical 1 1 1 Two-hybrid
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Positive Genetic
NBA1 YOL070C Protein involved in axial bud site selection genetic 1 1 1 Negative Genetic
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family physical 1 1 1 Two-hybrid
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 1 1 1 Phenotypic Suppression
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
PCL5 YHR071W Cyclin physical 1 1 1 Affinity Capture-Western
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
ATF2 YGR177C Alcohol acetyltransferase genetic 1 1 1 Dosage Rescue
ERP4 YOR016C Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Negative Genetic
PHO3 YBR092C Constitutively expressed acid phosphatase similar to Pho5p genetic 1 1 1 Phenotypic Enhancement
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic
FLO10 YKR102W Member of the FLO family of cell wall flocculation proteins genetic 1 1 1 Negative Genetic