Standard name Systematic name Name description Description
RSR1 YGR152C Ras-type GTPase Ras-type GTPase; required for bud site selection during both axial and bipolar budding, for morphological changes in response to mating pheromone, and for efficient cell fusion; recruits Cdc24p to the incipient bud site, activating its guanyl-nucleotide exchange factor activity and the Rho-like GTPase, Cdc42p; localizes to the plasma membrane, the incipient bud site, polarized growth sites, the cell division site and the vacuole membrane; Ras superfamily member similar to mammalian Rap GTPases
Visualize the interactome of RSR1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 19

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.872 0.987 0.981
Mito 0.051 NaN NaN
Nucleus 0.103 NaN NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus low signal

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RSR1 0 0 2 2 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 11 3 11 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Synthetic Rescue, Negative Genetic, Dosage Rescue, Dosage Rescue, Synthetic Rescue, Dosage Rescue, Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 7 3 7 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid
CDC42 YLR229C Small rho-like GTPase genetic 7 5 5 Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Synthetic Growth Defect, Negative Genetic, Phenotypic Suppression
CDC42 YLR229C Small rho-like GTPase physical 6 2 3 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
RAS2 YNL098C GTP-binding protein genetic 3 3 3 Dosage Rescue, Synthetic Lethality, Synthetic Rescue
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector genetic 3 2 3 Synthetic Lethality, Dosage Rescue, Dosage Rescue
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 3 2 3 Synthetic Lethality, Dosage Rescue, Dosage Rescue
BEM1 YBR200W Protein containing SH3-domains physical 3 2 2 Reconstituted Complex, Reconstituted Complex, PCA
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) genetic 3 2 2 Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p physical 2 2 2 Biochemical Activity, Affinity Capture-Western
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 2 2 2 Positive Genetic, Synthetic Rescue
BEM1 YBR200W Protein containing SH3-domains genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
NBA1 YOL070C Protein involved in axial bud site selection genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 2 1 Synthetic Growth Defect, Synthetic Rescue
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Two-hybrid
BOI2 YER114C Protein involved in polar growth genetic 1 1 1 Synthetic Growth Defect
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Synthetic Rescue
LTE1 YAL024C Protein similar to GDP/GTP exchange factors physical 1 1 1 Affinity Capture-Western
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Phenotypic Suppression
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p physical 1 1 1 PCA
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p genetic 1 1 1 Synthetic Growth Defect
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 1 1 1 Dosage Rescue
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 1 1 1 Synthetic Lethality
MLH3 YPL164C Protein involved in DNA mismatch repair and meiotic recombination physical 1 1 1 Affinity Capture-MS
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Dosage Rescue
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence physical 1 1 1 Two-hybrid
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Dosage Rescue
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
MSB2 YGR014W Mucin family member involved in various signaling pathways genetic 1 1 1 Phenotypic Enhancement
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) physical 1 1 1 Two-hybrid
BUD8 YLR353W Protein involved in bud-site selection genetic 1 1 1 Synthetic Rescue
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p genetic 1 1 1 Phenotypic Suppression
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Negative Genetic
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p physical 1 1 1 Two-hybrid
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex physical 1 1 1 Two-hybrid
RSR1 YGR152C Ras-type GTPase physical 1 1 1 Affinity Capture-Western
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
SPO12 YHR152W Nucleolar protein of unknown function genetic 1 1 1 Dosage Rescue
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Dosage Rescue
STE5 YDR103W Pheromone-responsive MAPK scaffold protein genetic 1 1 1 Phenotypic Enhancement
STE11 YLR362W Signal transducing MEK kinase genetic 1 1 1 Phenotypic Enhancement
STE4 YOR212W G protein beta subunit genetic 1 1 1 Phenotypic Enhancement
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Positive Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Positive Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Positive Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Positive Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
YJL118W YJL118W Protein of unknown function genetic 1 1 1 Negative Genetic
YLR285C-A YLR285C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOS9 YDR057W ER quality-control lectin genetic 1 1 1 Phenotypic Suppression
CUE3 YGL110C Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
ARF3 YOR094W Glucose-repressible ADP-ribosylation factor genetic 1 1 1 Phenotypic Suppression
ATG41 YPL250C Protein of unknown function genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic