Standard name Systematic name Name description Description
AST2 YER101C Lipid raft associated protein Lipid raft associated protein; overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST2 has a paralog, AST1, that arose from the whole genome duplication
Visualize the interactome of AST2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.952 0.977 0.967
Mito 0.083 NaN NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 937

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
AST2 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
COX4 YGL187C Subunit IV of cytochrome c oxidase genetic 2 1 2 Negative Genetic, Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 2 1 2 Negative Genetic, Negative Genetic
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 2 2 1 Reconstituted Complex, Two-hybrid
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase genetic 1 1 1 Positive Genetic
APC9 YLR102C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
AIM39 YOL053W Protein of unknown function genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Reconstituted Complex
TVP15 YDR100W Integral membrane protein physical 1 1 1 Two-hybrid
TVP18 YMR071C Integral membrane protein physical 1 1 1 Two-hybrid
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Synthetic Lethality
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Positive Genetic
ATG15 YCR068W Phospholipase genetic 1 1 1 Positive Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Positive Genetic
RPS14B YJL191W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
VBA5 YKR105C Plasma membrane protein of the Major Facilitator Superfamily (MFS) genetic 1 1 1 Positive Genetic
YLR297W YLR297W Protein of unknown function genetic 1 1 1 Positive Genetic
ATG39 YLR312C Transmembrane receptor with a role in nucleophagy genetic 1 1 1 Positive Genetic
FET4 YMR319C Low-affinity Fe(II) transporter of the plasma membrane genetic 1 1 1 Positive Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Positive Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Positive Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Positive Genetic
HES1 YOR237W Protein implicated in the regulation of ergosterol biosynthesis genetic 1 1 1 Positive Genetic
KIP2 YPL155C Kinesin-related motor protein involved in mitotic spindle positioning genetic 1 1 1 Positive Genetic
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes genetic 1 1 1 Positive Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
CBP6 YBR120C Mitochondrial protein required for translation of the COB mRNA genetic 1 1 1 Negative Genetic
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 1 1 1 Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Negative Genetic
ZTA1 YBR046C NADPH-dependent quinone reductase genetic 1 1 1 Negative Genetic
YBR053C YBR053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PTC4 YBR125C Cytoplasmic type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
MET8 YBR213W Bifunctional dehydrogenase and ferrochelatase genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
SHG1 YBR258C Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
GND2 YGR256W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Negative Genetic
YBR259W YBR259W Protein of unknown function genetic 1 1 1 Negative Genetic
RRT12 YCR045C Probable subtilisin-family protease genetic 1 1 1 Negative Genetic
MSH3 YCR092C Mismatch repair protein genetic 1 1 1 Negative Genetic
YCR102C YCR102C Putative quinone oxidoreductase genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs genetic 1 1 1 Negative Genetic
SRF1 YDL133W Regulator of phospholipase D (Spo14p) genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
INM2 YDR287W Inositol monophosphatase genetic 1 1 1 Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Negative Genetic
IOC3 YFR013W Subunit of the Isw1a complex genetic 1 1 1 Negative Genetic
NPY1 YGL067W NADH diphosphatase (pyrophosphatase) genetic 1 1 1 Negative Genetic
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Negative Genetic
PEF1 YGR058W Penta-EF-hand protein genetic 1 1 1 Negative Genetic
YGR067C YGR067C Putative protein of unknown function genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
RTC3 YHR087W Protein of unknown function involved in RNA metabolism genetic 1 1 1 Negative Genetic
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase genetic 1 1 1 Negative Genetic
NIT1 YIL164C Nitrilase genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
DLS1 YJL065C Subunit of ISW2/yCHRAC chromatin accessibility complex genetic 1 1 1 Negative Genetic
YJL070C YJL070C Putative metallo-dependent hydrolase superfamily protein genetic 1 1 1 Negative Genetic
GSM1 YJL103C Putative zinc cluster protein of unknown function genetic 1 1 1 Negative Genetic
FMP33 YJL161W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
BUD2 YKL092C GTPase activating factor for Rsr1p/Bud1p genetic 1 1 1 Negative Genetic
TPO5 YKL174C Protein involved in excretion of putrescine and spermidine genetic 1 1 1 Negative Genetic
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets genetic 1 1 1 Negative Genetic
MHT1 YLL062C S-methylmethionine-homocysteine methyltransferase genetic 1 1 1 Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 1 1 1 Negative Genetic
UBC12 YLR306W Enzyme that mediates the conjugation of Rub1p genetic 1 1 1 Negative Genetic
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex genetic 1 1 1 Negative Genetic
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
NMD4 YLR363C Protein that may be involved in nonsense-mediated mRNA decay genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Negative Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors genetic 1 1 1 Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Negative Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Negative Genetic
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Negative Genetic
TGL3 YMR313C Bifunctional triacylglycerol lipase and LPE acyltransferase genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
DMA2 YNL116W Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
DSE4 YNR067C Daughter cell-specific secreted protein with similarity to glucanases genetic 1 1 1 Negative Genetic
PFA4 YOL003C Palmitoyltransferase with autoacylation activity genetic 1 1 1 Negative Genetic
IRC10 YOL015W Protein of unknown function genetic 1 1 1 Negative Genetic
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis genetic 1 1 1 Negative Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
RPS30B YOR182C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
LEE1 YPL054W Zinc-finger protein of unknown function genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger genetic 1 1 1 Negative Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Negative Genetic
YPL199C YPL199C Protein involved in nonstop mRNA decay genetic 1 1 1 Negative Genetic
DIP5 YPL265W Dicarboxylic amino acid permease genetic 1 1 1 Negative Genetic
AXL1 YPR122W Haploid specific endoprotease of a-factor mating pheromone genetic 1 1 1 Negative Genetic
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Negative Genetic
CBP1 YJL209W Mitochondrial protein, regulator of COB mRNA stability and translation genetic 1 1 1 Negative Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Negative Genetic
QRI5 YLR204W Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
SHH3 YMR118C Putative mitochondrial inner membrane protein of unknown function genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
GSH2 YOL049W Glutathione synthetase genetic 1 1 1 Negative Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Negative Genetic
AIM19 YIL087C Protein of unknown function genetic 1 1 1 Negative Genetic