| BAT2 |
YJR148W |
Cytosolic branched-chain amino acid (BCAA) aminotransferase |
genetic |
7 |
3 |
6 |
Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic |
| ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Suppression |
| LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
regulation |
3 |
3 |
2 |
chromatin immunoprecipitation-qPCR evidence, DNA to cDNA expression microarray evidence, northern blot evidence |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
regulation |
3 |
3 |
2 |
chromatin immunoprecipitation-qPCR evidence, DNA to cDNA expression microarray evidence, northern blot evidence |
| BAT2 |
YJR148W |
Cytosolic branched-chain amino acid (BCAA) aminotransferase |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| ACO1 |
YLR304C |
Aconitase |
physical |
3 |
3 |
1 |
Affinity Capture-MS, Affinity Capture-Western, PCA |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RCR1 |
YBR005W |
Plasma membrane (PM) ubiquitin ligase-substrate adaptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VID24 |
YBR105C |
GID Complex regulatory subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SNF11 |
YDR073W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MPC1 |
YGL080W |
Highly conserved subunit of mitochondrial pyruvate carrier (MPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| PXP2 |
YJR111C |
Peroxisomal matrix protein with naturally active promoter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MAE1 |
YKL029C |
Mitochondrial malic enzyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PEX13 |
YLR191W |
Peroxisomal importomer complex component |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PHO84 |
YML123C |
High-affinity inorganic phosphate (Pi) transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SPO20 |
YMR017W |
Meiosis-specific subunit of the t-SNARE complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FAR8 |
YMR029C |
Protein involved in recovery from arrest in response to pheromone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GID8 |
YMR135C |
Subunit of GID Complex, binds strongly to central component Vid30p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TEA1 |
YOR337W |
Ty1 enhancer activator involved in Ty enhancer-mediated transcription |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
2 |
2 |
1 |
DNA to cDNA expression microarray evidence, quantitative polymerase chain reaction evidence |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| STP1 |
YDR463W |
Transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
regulation |
1 |
1 |
1 |
northern blot evidence |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| PUT3 |
YKL015W |
Transcriptional activator |
regulation |
1 |
1 |
1 |
northern blot evidence |
| AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP6 |
YBR055C |
Splicing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PRP6 |
YBR055C |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RMP1 |
YLR145W |
Subunit of RNase MRP |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| LEU4 |
YNL104C |
Alpha-isopropylmalate synthase (2-isopropylmalate synthase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BAT1 |
YHR208W |
Mitochondrial branched-chain amino acid (BCAA) aminotransferase |
physical |
1 |
1 |
1 |
PCA |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COX20 |
YDR231C |
Mitochondrial inner membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIM23 |
YNR017W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ILV2 |
YMR108W |
Acetolactate synthase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAS2 |
YDR020C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NRG1 |
YDR043C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX5 |
YDR244W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RMD5 |
YDR255C |
Component of GID Complex that confers ubiquitin ligase (U3) activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STP1 |
YDR463W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TYW3 |
YGL050W |
tRNA methyltransferase required for synthesis of wybutosine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMP2 |
YMR035W |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BCH1 |
YMR237W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOR1 |
YJR066W |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP5 |
YBR237W |
RNA helicase in the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC65 |
YML105C |
Subunit of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL24B |
YGR148C |
Ribosomal 60S subunit protein L24B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WHI5 |
YOR083W |
Repressor of G1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR078C |
YPR078C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAZ1 |
YPR140W |
Lyso-phosphatidylcholine acyltransferase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALD5 |
YER073W |
Mitochondrial aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| APE2 |
YKL157W |
Aminopeptidase yscII |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALG3 |
YBL082C |
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| ALD2 |
YMR170C |
Cytoplasmic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| ARO10 |
YDR380W |
Phenylpyruvate decarboxylase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |