SAC3 |
YDR159W |
mRNA export factor |
physical |
12 |
5 |
8 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Protein-peptide, Reconstituted Complex, Co-purification |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
physical |
11 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
THP1 |
YOL072W |
Nuclear pore-associated protein |
physical |
9 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
SFI1 |
YLL003W |
Centrin (Cdc31p)-binding protein required for SPB duplication |
physical |
8 |
4 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Protein-peptide, Two-hybrid, Affinity Capture-Western |
KAR1 |
YNL188W |
Protein involved in karyogamy and spindle pole body duplication |
genetic |
7 |
3 |
5 |
Dosage Rescue, Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Dosage Rescue, Dosage Rescue |
KAR1 |
YNL188W |
Protein involved in karyogamy and spindle pole body duplication |
physical |
6 |
3 |
5 |
Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Co-localization, Protein-peptide, Reconstituted Complex |
HEM15 |
YOR176W |
Ferrochelatase |
physical |
5 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
MPS1 |
YDL028C |
Dual-specificity kinase |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
3 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
CDC19 |
YAL038W |
Pyruvate kinase |
physical |
3 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-MS |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
SFI1 |
YLL003W |
Centrin (Cdc31p)-binding protein required for SPB duplication |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Growth Defect |
MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Lethality |
KIC1 |
YHR102W |
Protein kinase of the PAK/Ste20 family, required for cell integrity |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Two-hybrid |
KIC1 |
YHR102W |
Protein kinase of the PAK/Ste20 family, required for cell integrity |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Synthetic Growth Defect |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
PHB1 |
YGR132C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
CYT1 |
YOR065W |
Cytochrome c1 |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-MS |
AIM24 |
YJR080C |
Protein with a role in determining mitochondrial architecture |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ASF1 |
YJL115W |
Nucleosome assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADA2 |
YDR448W |
Transcription coactivator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AKL1 |
YBR059C |
Ser/Thr protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Far Western |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Dosage Rescue |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Dosage Rescue |
NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Co-purification |
PSA1 |
YDL055C |
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HEM13 |
YDR044W |
Coproporphyrinogen III oxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPY1 |
YGL067W |
NADH diphosphatase (pyrophosphatase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOS3 |
YPL116W |
Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Reconstituted Complex |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MSG5 |
YNL053W |
Dual-specificity protein phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TCO89 |
YPL180W |
Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP1 |
YOR098C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SPC97 |
YHR172W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COX2 |
Q0250 |
Subunit II of cytochrome c oxidase (Complex IV) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAA1 |
YOR317W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FZO1 |
YBR179C |
Mitofusin, protein involved in mitochondrial outer membrane fusion |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
COX1 |
Q0045 |
Subunit I of cytochrome c oxidase (Complex IV) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Dosage Rescue |
NBP1 |
YLR457C |
Spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |