| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
9 |
4 |
8 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
physical |
5 |
4 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, PCA |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
3 |
3 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
physical |
3 |
3 |
3 |
Affinity Capture-Western, Affinity Capture-MS, PCA |
| GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
3 |
3 |
3 |
Synthetic Rescue, Synthetic Lethality, Phenotypic Enhancement |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Phenotypic Enhancement |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
2 |
2 |
2 |
Biochemical Activity, PCA |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SFA1 |
YDL168W |
Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
physical |
2 |
1 |
1 |
PCA, PCA |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
physical |
2 |
1 |
1 |
PCA, PCA |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MET32 |
YDR253C |
Zinc-finger DNA-binding transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MET4 |
YNL103W |
Leucine-zipper transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
physical |
1 |
1 |
1 |
PCA |
| GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAW1 |
YAL027W |
5'- and 3'-flap DNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NIS1 |
YNL078W |
Protein involved in axial bud site selection |
physical |
1 |
1 |
1 |
Two-hybrid |
| PCL1 |
YNL289W |
Cyclin, interacts with cyclin-dependent kinase Pho85p |
physical |
1 |
1 |
1 |
Biochemical Activity |
| VHR2 |
YER064C |
Non-essential nuclear protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| SES1 |
YDR023W |
Cytosolic seryl-tRNA synthetase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| YML096W |
YML096W |
Putative protein with similarity to asparagine synthetases |
physical |
1 |
1 |
1 |
Biochemical Activity |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| MTW1 |
YAL034W-A |
Essential component of the MIND kinetochore complex |
physical |
1 |
1 |
1 |
Biochemical Activity |
| NOG1 |
YPL093W |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIM11 |
YMR139W |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MFT1 |
YML062C |
Subunit of the THO complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| NTA1 |
YJR062C |
Amidase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| PRS1 |
YKL181W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RTT106 |
YNL206C |
Histone chaperone |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SCT1 |
YBL011W |
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SIP5 |
YMR140W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| WWM1 |
YFL010C |
WW domain containing protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| YKL091C |
YKL091C |
Putative phosphatidylinositol/phosphatidylcholine transfer protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGK1 |
YCR012W |
3-phosphoglycerate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPP1 |
YCR026C |
Nucleotide pyrophosphatase/phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPE1 |
YHR075C |
Protein with carboxyl methyl esterase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSY1 |
YDR160W |
Component of the SPS plasma membrane amino acid sensor system |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOP4 |
YJL192C |
ER-membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP35 |
YNL122C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KCS1 |
YDR017C |
Inositol hexakisphosphate and inositol heptakisphosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR1 |
YGL013C |
Transcription factor that regulates the pleiotropic drug response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC2 |
YLR357W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPC2 |
YDR213W |
Sterol regulatory element binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POP4 |
YBR257W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIN10 |
YFR032C-B |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YLL053C |
YLL053C |
Putative protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS31 |
YDR472W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QNS1 |
YHR074W |
Glutamine-dependent NAD(+) synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS1 |
YKR063C |
Endonuclease involved in pre-rRNA processing at both ends of ITS2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIB2 |
YOL066C |
Bifunctional DRAP deaminase tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR050W-A |
YHR050W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUL1 |
YKL034W |
Subunit of the DSC ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL106C-A |
YKL106C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL20 |
YKR085C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLL056C |
YLL056C |
NADH-dependent aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR084W |
YMR084W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR192C-C |
YOR192C-C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEP1 |
YNL128W |
PTEN homolog with no demonstrated inositol lipid phosphatase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP12 |
YJL197W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DRE2 |
YKR071C |
Component of the cytosolic Fe-S protein assembly (CIA) machinery |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| BOI1 |
YBL085W |
Protein involved in polar growth, functionally redundant with Boi2p |
physical |
1 |
1 |
1 |
Two-hybrid |
| CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GRX1 |
YCL035C |
Glutathione-dependent disulfide oxidoreductase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC24 |
YLR323C |
General splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ISC10 |
YER180C |
Meiosis-specific MAPK inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAK1 |
YFL029C |
Cyclin-dependent kinase-activating kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| JIP5 |
YPR169W |
Protein required for biogenesis of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD4 |
YJR092W |
Anillin-like protein involved in bud-site selection |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| BNI5 |
YNL166C |
Linker protein responsible for recruitment of myosin to the bud neck |
physical |
1 |
1 |
1 |
PCA |
| BUD6 |
YLR319C |
Actin- and formin-interacting protein |
physical |
1 |
1 |
1 |
PCA |
| DPC29 |
YGR021W |
Putative mitochondrial protein of unknown function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ETR1 |
YBR026C |
2-enoyl thioester reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDP3 |
YNL009W |
Peroxisomal NADP-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMR3 |
YPR013C |
Putative zinc finger protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GAS3 |
YMR215W |
Putative 1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| JJJ3 |
YJR097W |
Iron-binding protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| GRX3 |
YDR098C |
Glutathione-dependent oxidoreductase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| FIT2 |
YOR382W |
Mannoprotein that is incorporated into the cell wall |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
