Standard name Systematic name Name description Description
NUP42 YDR192C FG-nucleoporin component of central core of the nuclear pore complex FG-nucleoporin component of central core of the nuclear pore complex; also part of the nuclear pore complex (NPC) cytoplasmic filaments; contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier and is involved in gene tethering at the nuclear periphery; interacts with Gle1p; human homolog NUP42 can complement yeast mutant
Visualize the interactome of NUP42
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
NUP42 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export physical 17 5 7 Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Co-purification
GLE1 YDL207W Cytoplasmic nucleoporin required for polyadenylated mRNA export genetic 10 5 6 Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 9 5 8 Synthetic Lethality, Synthetic Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
CRM1 YGR218W Nuclear export factor, exportin physical 7 4 6 Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Reconstituted Complex, Co-crystal Structure
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 7 2 5 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 6 2 4 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KAP95 YLR347C Karyopherin beta physical 5 3 5 Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 5 2 5 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 5 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLX9 YGR081C Protein required for pre-rRNA processing genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex genetic 5 4 2 Synthetic Growth Defect, Synthetic Lethality, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
GSP1 YLR293C Ran GTPase physical 4 4 3 Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 3 2 3 Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VAC14 YLR386W Enzyme regulator genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KAP123 YER110C Karyopherin beta physical 2 2 2 Two-hybrid, Affinity Capture-MS
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 physical 2 2 2 Two-hybrid, Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 2 2 2 Co-purification, Affinity Capture-MS
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) physical 2 2 2 Affinity Capture-MS, Two-hybrid
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 2 2 2 Synthetic Lethality, Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
CRN1 YLR429W Coronin genetic 2 1 2 Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GFD1 YMR255W Coiled-coiled protein of unknown function physical 2 1 2 Two-hybrid, Two-hybrid
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 2 1 2 Negative Genetic, Negative Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 2 1 2 Negative Genetic, Negative Genetic
SLH1 YGR271W Subunit of ribosome-associated quality control trigger complex (RQT) genetic 2 1 2 Negative Genetic, Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 2 1 2 Negative Genetic, Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 2 1 2 Negative Genetic, Negative Genetic
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 2 1 1 Negative Genetic, Negative Genetic
CIN1 YOR349W Tubulin folding factor D involved in beta-tubulin (Tub2p) folding genetic 2 1 1 Negative Genetic, Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly physical 1 1 1 Reconstituted Complex
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) physical 1 1 1 Two-hybrid
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export genetic 1 1 1 Synthetic Growth Defect
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 1 1 1 Dosage Rescue
IOC3 YFR013W Subunit of the Isw1a complex genetic 1 1 1 Negative Genetic
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ATG26 YLR189C UDP-glucose:sterol glucosyltransferase genetic 1 1 1 Negative Genetic
MTR10 YOR160W Nuclear import receptor physical 1 1 1 Two-hybrid
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NIC96 YFR002W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
NSP1 YJL041W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
NUP159 YIL115C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex physical 1 1 1 Two-hybrid
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis physical 1 1 1 Two-hybrid
IPA1 YJR141W Protein implicated in pre-mRNA processing and proteasomal degradation genetic 1 1 1 Negative Genetic
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MSN5 YDR335W Karyopherin physical 1 1 1 Affinity Capture-MS
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP157 YER105C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
CNL1 YDR357C Subunit of the BLOC-1 complex involved in endosomal maturation genetic 1 1 1 Negative Genetic
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Phenotypic Suppression
ATG8 YBL078C Ub-like protein physical 1 1 1 Affinity Capture-MS
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family physical 1 1 1 Reconstituted Complex
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Negative Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 1 1 1 Reconstituted Complex
MTR2 YKL186C mRNA transport regulator physical 1 1 1 Reconstituted Complex
MTR2 YKL186C mRNA transport regulator genetic 1 1 1 Negative Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP100 YKL068W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 Two-hybrid
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 1 1 1 Positive Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
SFB2 YNL049C Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SML1 YML058W Ribonucleotide reductase inhibitor physical 1 1 1 Affinity Capture-MS
SER3 YER081W 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase physical 1 1 1 Two-hybrid
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex physical 1 1 1 Affinity Capture-MS
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Affinity Capture-MS
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Reconstituted Complex
WHI3 YNL197C RNA binding protein that modulates mRNA stability physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
PLC1 YPL268W Phospholipase C genetic 1 1 1 Synthetic Growth Defect
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
RPB4 YJL140W RNA polymerase II subunit B32 genetic 1 1 1 Negative Genetic
TRM3 YDL112W 2'-O-ribose methyltransferase genetic 1 1 1 Positive Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Growth Defect
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
STB4 YMR019W Putative transcription factor genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Phenotypic Suppression
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Positive Genetic
TAG1 YLR173W Vacuolar membrane protein involved in termination of autophagy genetic 1 1 1 Positive Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
YSF3 YNL138W-A Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
YPR172W YPR172W Protein of unknown function genetic 1 1 1 Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Positive Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
MPS3 YJL019W Nuclear envelope protein genetic 1 1 1 Synthetic Rescue
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
MET13 YGL125W Major isozyme of methylenetetrahydrofolate reductase genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Positive Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
NCE101 YJL205C Protein of unknown function genetic 1 1 1 Negative Genetic
ADF1 YCL058W-A Transcriptional repressor encoded by the FYV5 antisense strand genetic 1 1 1 Negative Genetic