| RNQ1 |
YCL028W |
[PIN(+)] prion |
physical |
12 |
5 |
11 |
Co-crystal Structure, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Co-fractionation |
| SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
5 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Protein-peptide, Affinity Capture-Western, Affinity Capture-Western |
| SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
genetic |
4 |
1 |
4 |
Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
3 |
2 |
3 |
Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
3 |
2 |
2 |
Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-RNA |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| TAH1 |
YCR060W |
Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
| MKK2 |
YPL140C |
MAPKK involved in the protein kinase C signaling pathway |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
genetic |
2 |
1 |
1 |
Dosage Rescue, Dosage Rescue |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BUD14 |
YAR014C |
Protein involved in bud-site selection |
physical |
1 |
1 |
1 |
Two-hybrid |
| CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Two-hybrid |
| HRP1 |
YOL123W |
Subunit of cleavage factor I |
physical |
1 |
1 |
1 |
Two-hybrid |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LSM4 |
YER112W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| LCD1 |
YDR499W |
Essential protein required for the DNA integrity checkpoint pathways |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RFC3 |
YNL290W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
physical |
1 |
1 |
1 |
Two-hybrid |
| INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LAP2 |
YNL045W |
Leucyl aminopeptidase yscIV with epoxide hydrolase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GLC8 |
YMR311C |
Regulatory subunit of protein phosphatase 1 (Glc7p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SML1 |
YML058W |
Ribonucleotide reductase inhibitor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TDP1 |
YBR223C |
Tyrosyl-DNA phosphodiesterase I |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SWM1 |
YDR260C |
Subunit of the anaphase-promoting complex (APC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STE4 |
YOR212W |
G protein beta subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RNR3 |
YIL066C |
Minor isoform of large subunit of ribonucleotide-diphosphate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| URA3 |
YEL021W |
Orotidine-5'-phosphate (OMP) decarboxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAE1 |
YBR261C |
AdoMet-dependent proline methyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
1 |
1 |
1 |
Two-hybrid |
| SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
physical |
1 |
1 |
1 |
Two-hybrid |
| ROX3 |
YBL093C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SRB4 |
YER022W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SRB6 |
YBR253W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SRB7 |
YDR308C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
physical |
1 |
1 |
1 |
Two-hybrid |
| UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VID24 |
YBR105C |
GID Complex regulatory subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOH1 |
YJL171C |
GPI-anchored cell wall protein of unknown function |
physical |
1 |
1 |
1 |
FRET |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| TSA2 |
YDR453C |
Stress inducible cytoplasmic thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| THI2 |
YBR240C |
Transcriptional activator of thiamine biosynthetic genes |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| YNL208W |
YNL208W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| RSM24 |
YDR175C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL043W |
YJL043W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR068C |
YNR068C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR012W |
YOR012W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPG1 |
YGL121C |
Proposed gamma subunit of the heterotrimeric G protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| BTN2 |
YGR142W |
v-SNARE binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CWC24 |
YLR323C |
General splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLG1 |
YGL215W |
Cyclin-like protein that interacts with Pho85p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
physical |
1 |
1 |
1 |
Two-hybrid |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GAL80 |
YML051W |
Transcriptional regulator involved in the repression of GAL genes |
physical |
1 |
1 |
1 |
Two-hybrid |
| MCA1 |
YOR197W |
Ca2+-dependent cysteine protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
1 |
1 |
1 |
Two-hybrid |
| NVJ1 |
YHR195W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| PIH1 |
YHR034C |
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
physical |
1 |
1 |
1 |
Two-hybrid |
| MRPL11 |
YDL202W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MUK1 |
YPL070W |
Guanine nucleotide exchange factor (GEF) |
physical |
1 |
1 |
1 |
Two-hybrid |
| CWP2 |
YKL096W-A |
Covalently linked cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNH201 |
YNL072W |
Ribonuclease H2 catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MSA1 |
YOR066W |
Activator of G1-specific transcription factors MBF and SBF |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NFU1 |
YKL040C |
Protein involved in Fe-S cluster transfer to mitochondrial clients |
physical |
1 |
1 |
1 |
Two-hybrid |
| RKR1 |
YMR247C |
RING domain E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Dosage Rescue |