Standard name Systematic name Name description Description
SAR1 YPL218W ARF family GTPase ARF family GTPase; component of the COPII vesicle coat; required for transport vesicle formation during ER to Golgi protein transport; lowers membrane rigidity aiding vesicle formation; localizes to ER-mitochondrial contact sites where it enhances membrane curvature, thereby reducing contact size via its N-terminal amphipathic helix; regulates mitochondrial fission and fusion dynamics
Visualize the interactome of SAR1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SAR1 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 10 5 9 Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Co-purification, Co-fractionation, Reconstituted Complex, Biochemical Activity, Reconstituted Complex
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 8 4 7 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Rescue
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 5 3 5 Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Co-purification, Affinity Capture-MS
BET1 YIL004C Type II membrane protein required for vesicular transport physical 4 2 4 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
SED4 YCR067C Integral ER membrane protein that stimulates Sar1p GTPase activity genetic 3 3 3 Dosage Rescue, Synthetic Lethality, Synthetic Growth Defect
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 3 2 3 Dosage Rescue, Dosage Rescue, Synthetic Rescue
EMP24 YGL200C Component of the p24 complex physical 3 3 2 Affinity Capture-Western, Reconstituted Complex, Co-purification
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) physical 3 3 2 Biochemical Activity, Co-crystal Structure, Reconstituted Complex
SEC22 YLR268W R-SNARE protein physical 3 2 2 Affinity Capture-Western, Affinity Capture-Western, Co-purification
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SED5 YLR026C cis-Golgi t-SNARE syntaxin physical 2 2 2 Affinity Capture-Western, Co-purification
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
HIP1 YGR191W High-affinity histidine permease physical 2 2 1 Affinity Capture-Western, Co-purification
NEL1 YHR035W Activator of Sar1p GTPase activity physical 2 2 1 Biochemical Activity, Reconstituted Complex
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HAP1 YLR256W Zinc finger transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Affinity Capture-MS
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
PRE1 YER012W Beta 4 subunit of the 20S proteasome genetic 1 1 1 Dosage Lethality
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation physical 1 1 1 Affinity Capture-MS
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport physical 1 1 1 Affinity Capture-Western
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Dosage Lethality
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Dosage Lethality
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 1 1 1 Dosage Rescue
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Affinity Capture-MS
CRN1 YLR429W Coronin physical 1 1 1 Affinity Capture-MS
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
CYC8 YBR112C General transcriptional co-repressor physical 1 1 1 Affinity Capture-MS
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Dosage Rescue
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding physical 1 1 1 Reconstituted Complex
TLG2 YOL018C Syntaxin-like t-SNARE physical 1 1 1 Co-purification
TVP15 YDR100W Integral membrane protein physical 1 1 1 Two-hybrid
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
SED4 YCR067C Integral ER membrane protein that stimulates Sar1p GTPase activity physical 1 1 1 Reconstituted Complex
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat physical 1 1 1 Reconstituted Complex
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II physical 1 1 1 Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
UTP10 YJL109C Nucleolar protein physical 1 1 1 Affinity Capture-MS
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Dosage Rescue
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) physical 1 1 1 Reconstituted Complex
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 1 1 1 Dosage Rescue
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
ATG23 YLR431C Peripheral membrane protein required for autophagy and CVT physical 1 1 1 Affinity Capture-MS
ATG8 YBL078C Ub-like protein physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
ERV41 YML067C Protein localized to COPII-coated vesicles physical 1 1 1 Affinity Capture-Western
ERV46 YAL042W Protein localized to COPII-coated vesicles physical 1 1 1 Affinity Capture-Western
GAP1 YKR039W General amino acid permease physical 1 1 1 Affinity Capture-Western
ERV29 YGR284C Protein localized to COPII-coated vesicles physical 1 1 1 Affinity Capture-Western
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ERV14 YGL054C COPII-coated vesicle protein physical 1 1 1 Reconstituted Complex
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HRD3 YLR207W ER membrane protein that plays a central role in ERAD genetic 1 1 1 Dosage Rescue
NEL1 YHR035W Activator of Sar1p GTPase activity genetic 1 1 1 Synthetic Growth Defect
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 1 1 1 Dosage Rescue
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Dosage Rescue
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 1 1 1 Phenotypic Suppression
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 1 1 1 Dosage Rescue
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS