SCW10 |
YMR305C |
Cell wall protein with similarity to glucanases |
genetic |
5 |
2 |
5 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
4 |
3 |
4 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BMT2 |
YBR141C |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BNI1 |
YNL271C |
Formin |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI6 |
YLR182W |
Transcription cofactor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
NSA1 |
YGL111W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMP1 |
YLR145W |
Subunit of RNase MRP |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RSC58 |
YLR033W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL24 |
YMR193W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
BGL2 |
YGR282C |
Endo-beta-1,3-glucanase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTC5 |
YOR090C |
Mitochondrial type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Negative Genetic |
LUG1 |
YLR352W |
Protein of unknown function with similarity to F-box proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD9 |
YGR041W |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAN1 |
YDR143C |
Ubiquitin-protein ligase |
physical |
1 |
1 |
1 |
Two-hybrid |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
FIG1 |
YBR040W |
Integral membrane protein required for efficient mating |
genetic |
1 |
1 |
1 |
Positive Genetic |
COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAL1 |
YDR348C |
Protein of unknown function thought to be involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX13 |
YLR191W |
Peroxisomal importomer complex component |
physical |
1 |
1 |
1 |
Two-hybrid |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CHS3 |
YBR023C |
Chitin synthase III |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
OTU1 |
YFL044C |
Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SHY1 |
YGR112W |
Mitochondrial inner membrane protein required for complex IV assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SED1 |
YDR077W |
Major stress-induced structural GPI-cell wall glycoprotein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC3 |
YER008C |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDD1 |
YEL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC53 |
YFL045C |
Phosphomannomutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIP5 |
YGL161C |
Protein that interacts with Rab GTPases |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
CQD1 |
YPL109C |
UbiB family mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERT1 |
YBR239C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDL1 |
YLR188W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEX1 |
YGL203C |
Cell death protease essential for hypochlorite-induced apoptosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
GRE3 |
YHR104W |
Aldose reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSM24 |
YDR175C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSC2 |
YGR032W |
Catalytic subunit of 1,3-beta-glucan synthase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG15 |
YCR068W |
Phospholipase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |