Standard name Systematic name Name description Description
YPD1 YDL235C Osmotic stress-responsive phosphorelay intermediate sensor protein Osmotic stress-responsive phosphorelay intermediate sensor protein; phosphorylated by the plasma membrane sensor Sln1p in response to osmotic stress and then in turn phosphorylates the response regulators Ssk1p in the cytosol and Skn7p in the nucleus
Visualize the interactome of YPD1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.987 1.0 0.938
Vac/Vac Memb NaN NaN 0.062

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 6330

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
YPD1 0 0 0 2 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator physical 19 5 14 Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, PCA, Two-hybrid, Two-hybrid, PCA, PCA, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor physical 14 4 11 Co-crystal Structure, Two-hybrid, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Two-hybrid, Biochemical Activity, Biochemical Activity, Co-crystal Structure, Biochemical Activity, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex
SKN7 YHR206W Nuclear response regulator and transcription factor physical 5 4 5 Biochemical Activity, Affinity Capture-Western, Two-hybrid, Biochemical Activity, PCA
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 4 2 3 Synthetic Rescue, Positive Genetic, Synthetic Rescue, Synthetic Rescue
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 3 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator genetic 2 2 2 Synthetic Rescue, Positive Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 2 2 2 Synthetic Rescue, Positive Genetic
PTP2 YOR208W Phosphotyrosine-specific phosphatase genetic 2 2 2 Dosage Rescue, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Positive Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Positive Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I genetic 1 1 1 Positive Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
MBP1 YDL056W Transcription factor genetic 1 1 1 Positive Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Positive Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Synthetic Growth Defect
RAD51 YER095W Strand exchange protein genetic 1 1 1 Positive Genetic
PIL1 YGR086C Eisosome core component genetic 1 1 1 Positive Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Positive Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
INP52 YNL106C Polyphosphatidylinositol phosphatase genetic 1 1 1 Positive Genetic
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p genetic 1 1 1 Synthetic Rescue
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase genetic 1 1 1 Positive Genetic
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Positive Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
SKI3 YPR189W Ski complex component and TPR protein genetic 1 1 1 Positive Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Positive Genetic
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase genetic 1 1 1 Positive Genetic
FAR1 YJL157C CDK inhibitor and nuclear anchor genetic 1 1 1 Positive Genetic
KDX1 YKL161C Protein kinase physical 1 1 1 PCA
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Positive Genetic
INM1 YHR046C Inositol monophosphatase genetic 1 1 1 Positive Genetic
KNS1 YLL019C Protein kinase involved in negative regulation of PolIII transcription genetic 1 1 1 Positive Genetic
DMA1 YHR115C Ubiquitin-protein ligase (E3) genetic 1 1 1 Positive Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PTP3 YER075C Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Negative Genetic
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Positive Genetic
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Positive Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 PCA
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent physical 1 1 1 Affinity Capture-MS
YSR3 YKR053C Dihydrosphingosine 1-phosphate phosphatase genetic 1 1 1 Positive Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
RCK1 YGL158W Protein kinase involved in oxidative stress response genetic 1 1 1 Positive Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Synthetic Lethality
FPK1 YNR047W Ser/Thr protein kinase genetic 1 1 1 Positive Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Positive Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Positive Genetic
RIM11 YMR139W Protein kinase genetic 1 1 1 Negative Genetic
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role genetic 1 1 1 Positive Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
BNI4 YNL233W Targeting subunit for Glc7p protein phosphatase genetic 1 1 1 Negative Genetic
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p genetic 1 1 1 Negative Genetic
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Positive Genetic
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Synthetic Lethality
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
APN1 YKL114C Major apurinic/apyrimidinic endonuclease physical 1 1 1 Affinity Capture-MS
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Positive Genetic
PHO80 YOL001W Cyclin genetic 1 1 1 Positive Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Positive Genetic
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RAX1 YOR301W Protein involved in establishing bud site selection physical 1 1 1 PCA
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Reconstituted Complex
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
FRK1 YPL141C Protein kinase of unknown cellular role genetic 1 1 1 Positive Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Negative Genetic
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation genetic 1 1 1 Positive Genetic
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
GUT1 YHL032C Glycerol kinase genetic 1 1 1 Positive Genetic
KIN4 YOR233W Serine/threonine protein kinase genetic 1 1 1 Positive Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
SKS1 YPL026C Putative serine/threonine protein kinase genetic 1 1 1 Positive Genetic
TWF1 YGR080W Twinfilin genetic 1 1 1 Positive Genetic
DAK1 YML070W Dihydroxyacetone kinase genetic 1 1 1 Positive Genetic
LCB4 YOR171C Sphingoid long-chain base kinase genetic 1 1 1 Positive Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
MRK1 YDL079C Glycogen synthase kinase 3 (GSK-3) homolog genetic 1 1 1 Positive Genetic
VHS1 YDR247W Cytoplasmic serine/threonine protein kinase genetic 1 1 1 Positive Genetic
PHO3 YBR092C Constitutively expressed acid phosphatase similar to Pho5p genetic 1 1 1 Negative Genetic
YMR1 YJR110W Phosphatidylinositol 3-phosphate (PI3P) phosphatase genetic 1 1 1 Positive Genetic
YCH1 YGR203W Phosphatase with sequence similarity to Mih1p genetic 1 1 1 Positive Genetic