Standard name Systematic name Name description Description
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex Transverse filament protein of the synaptonemal complex; required for normal levels of meiotic recombination and pairing between homologous chromosome during meiosis; required for meiotic recombination between non-allelc sites; potential Cdc28p substrate
Visualize the interactome of ZIP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data 391

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
ZIP1 3 4 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PCH2 YBR186W Hexameric ring ATPase that remodels chromosome axis protein Hop1p genetic 8 4 7 Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex physical 4 1 3 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 3 3 3 Synthetic Rescue, Dosage Rescue, Phenotypic Enhancement
RED1 YLR263W Protein component of the synaptonemal complex axial elements genetic 3 3 3 Dosage Rescue, Phenotypic Enhancement, Synthetic Rescue
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 3 2 3 Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
CLB1 YGR108W B-type cyclin involved in cell cycle progression genetic 3 2 3 Dosage Rescue, Dosage Rescue, Phenotypic Suppression
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 3 2 3 Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression
CST9 YLR394W SUMO E3 ligase physical 3 3 2 Affinity Capture-Western, Two-hybrid, Co-localization
LCD1 YDR499W Essential protein required for the DNA integrity checkpoint pathways genetic 3 2 2 Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Suppression
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex physical 3 1 2 Two-hybrid, Two-hybrid, Two-hybrid
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 2 2 Phenotypic Enhancement, Dosage Lethality
CDC5 YMR001C Polo-like kinase required for mitotic exit genetic 2 2 2 Dosage Rescue, Phenotypic Suppression
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
NDT80 YHR124W Meiosis-specific transcription factor genetic 2 2 2 Synthetic Rescue, Phenotypic Suppression
SPO11 YHL022C Meiosis-specific protein required for meiotic recombination genetic 2 2 2 Phenotypic Enhancement, Phenotypic Suppression
MPS3 YJL019W Nuclear envelope protein physical 2 2 2 Two-hybrid, Affinity Capture-MS
ZAP1 YJL056C Zinc-regulated transcription factor regulation 2 1 2 DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 2 1 2 Phenotypic Suppression, Phenotypic Suppression
RAD51 YER095W Strand exchange protein genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 2 1 2 Negative Genetic, Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 2 2 1 Two-hybrid, Reconstituted Complex
NNF1 YJR112W Essential component of the outer kinetochore MIND complex physical 2 1 1 Two-hybrid, Two-hybrid
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 2 1 1 Two-hybrid, Two-hybrid
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER physical 2 1 1 Two-hybrid, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
SRB4 YER022W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
APL3 YBL037W Alpha-adaptin physical 1 1 1 Two-hybrid
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Synthetic Growth Defect
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
HHF2 YNL030W Histone H4 genetic 1 1 1 Phenotypic Suppression
HTB2 YBL002W Histone H2B physical 1 1 1 Affinity Capture-MS
KIN3 YAR018C Nonessential serine/threonine protein kinase physical 1 1 1 Two-hybrid
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Phenotypic Suppression
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Two-hybrid
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Phenotypic Enhancement
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping physical 1 1 1 Two-hybrid
MSH4 YFL003C Protein involved in meiotic recombination genetic 1 1 1 Phenotypic Suppression
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA genetic 1 1 1 Negative Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Phenotypic Enhancement
HTB1 YDR224C Histone H2B physical 1 1 1 Affinity Capture-MS
DMC1 YER179W Meiosis-specific recombinase required for double-strand break repair genetic 1 1 1 Phenotypic Enhancement
MLH3 YPL164C Protein involved in DNA mismatch repair and meiotic recombination genetic 1 1 1 Phenotypic Suppression
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Phenotypic Enhancement
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription genetic 1 1 1 Negative Genetic
ETP1 YHL010C Protein of unknown function required for growth on ethanol physical 1 1 1 Two-hybrid
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone physical 1 1 1 Two-hybrid
GYP5 YPL249C GTPase-activating protein (GAP) for yeast Rab family members physical 1 1 1 Two-hybrid
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen physical 1 1 1 Two-hybrid
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase genetic 1 1 1 Negative Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) physical 1 1 1 Biochemical Activity
RED1 YLR263W Protein component of the synaptonemal complex axial elements physical 1 1 1 Two-hybrid
ECM11 YDR446W Meiosis-specific protein genetic 1 1 1 Phenotypic Suppression
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Two-hybrid
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 1 1 1 Phenotypic Enhancement
MSH5 YDL154W Protein of the MutS family genetic 1 1 1 Phenotypic Enhancement
SPC72 YAL047C Gamma-tubulin small complex (gamma-TuSC) receptor physical 1 1 1 Two-hybrid
CNL1 YDR357C Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
BLI1 YKL061W Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Phenotypic Enhancement
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Positive Genetic
HOP1 YIL072W Meiosis-specific protein required for chromosome synapsis genetic 1 1 1 Phenotypic Suppression
KAR3 YPR141C Minus-end-directed microtubule motor physical 1 1 1 Two-hybrid
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint physical 1 1 1 Two-hybrid
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 1 1 1 Two-hybrid
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Synthetic Growth Defect
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 1 1 1 Phenotypic Suppression
SEC9 YGR009C t-SNARE protein required for secretory vesicle-plasma membrane fusion physical 1 1 1 Two-hybrid
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Phenotypic Enhancement
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Phenotypic Suppression
IMP1 YMR150C Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Negative Genetic
NNF2 YGR089W Protein that exhibits physical and genetic interactions with Rpb8p physical 1 1 1 Two-hybrid
SPA2 YLL021W Component of the polarisome physical 1 1 1 Two-hybrid
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
REC8 YPR007C Meiosis-specific component of the sister chromatid cohesion complex genetic 1 1 1 Phenotypic Enhancement
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway physical 1 1 1 Two-hybrid
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Negative Genetic
TPM2 YIL138C Minor isoform of tropomyosin physical 1 1 1 Two-hybrid
MET4 YNL103W Leucine-zipper transcriptional activator physical 1 1 1 Two-hybrid
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Negative Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Two-hybrid
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
RQC2 YPL009C Component of the Ribosome Quality Control (RQC) complex physical 1 1 1 Two-hybrid
SPR3 YGR059W Sporulation-specific homolog of the CDC3/10/11/12 family of genes physical 1 1 1 Two-hybrid
YTA6 YPL074W Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family physical 1 1 1 Two-hybrid
HEM4 YOR278W Uroporphyrinogen III synthase genetic 1 1 1 Negative Genetic
SPO22 YIL073C Meiosis-specific protein essential for chromosome synapsis genetic 1 1 1 Phenotypic Suppression
YGL188C-A YGL188C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic