Standard name Systematic name Name description Description
CNA1 YLR433C Calcineurin A Calcineurin A; one isoform (the other is Cmp2p) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1; regulates the function of Aly1p alpha-arrestin; CNA1 has a paralog, CMP2, that arose from the whole genome duplication
Visualize the interactome of CNA1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.995 0.985 1.0

GFP localization & abundance

GFP localization GFP abundance
ambiguous 7040

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CNA1 0 0 0 1 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CNB1 YKL190W Calcineurin B physical 6 2 6 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-MS
CMD1 YBR109C Calmodulin physical 5 3 5 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Co-crystal Structure
RCN1 YKL159C Protein involved in calcineurin regulation during calcium signaling physical 5 4 3 Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Biochemical Activity
ALY1 YKR021W Alpha arrestin, substrate of calcineurin physical 5 4 2 Two-hybrid, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Biochemical Activity
CMP2 YML057W Calcineurin A genetic 4 2 4 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 4 2 3 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Rescue
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p physical 4 3 2 Protein-peptide, Reconstituted Complex, Reconstituted Complex, Biochemical Activity
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 3 2 3 Affinity Capture-Western, Two-hybrid, Two-hybrid
SLM2 YNL047C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p physical 3 1 3 Two-hybrid, Two-hybrid, Two-hybrid
ROD1 YOR018W Alpha-arrestin involved in ubiquitin-dependent endocytosis physical 3 2 2 Reconstituted Complex, Reconstituted Complex, Biochemical Activity
CMP2 YML057W Calcineurin A physical 2 2 2 Co-purification, Reconstituted Complex
FRT1 YOR324C Tail-anchored ER membrane protein of unknown function physical 2 1 2 Two-hybrid, Two-hybrid
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 1 2 Negative Genetic, Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 2 1 2 Negative Genetic, Negative Genetic
BOI2 YER114C Protein involved in polar growth physical 2 2 1 Reconstituted Complex, Biochemical Activity
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes physical 2 2 1 Reconstituted Complex, Biochemical Activity
DIG2 YDR480W MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 2 2 1 Reconstituted Complex, Biochemical Activity
ELM1 YKL048C Serine/threonine protein kinase physical 2 2 1 Reconstituted Complex, Biochemical Activity
MLF3 YNL074C Serine-rich protein of unknown function physical 2 2 1 Reconstituted Complex, Biochemical Activity
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat physical 2 2 1 Reconstituted Complex, Biochemical Activity
SKG3 YLR187W Protein of unknown function physical 2 2 1 Reconstituted Complex, Biochemical Activity
UBX7 YBR273C UBX (ubiquitin regulatory X) domain-containing protein physical 2 2 1 Reconstituted Complex, Biochemical Activity
UME6 YDR207C Rpd3L histone deacetylase complex subunit physical 2 2 1 Reconstituted Complex, Biochemical Activity
TDA1 YMR291W Protein kinase of unknown cellular role physical 2 2 1 Reconstituted Complex, Biochemical Activity
ZRG17 YNR039C Endoplasmic reticulum zinc transporter physical 2 2 1 Reconstituted Complex, Biochemical Activity
ATG13 YPR185W Regulatory subunit of the Atg1p signaling complex physical 2 2 1 Reconstituted Complex, Biochemical Activity
AIM3 YBR108W Protein that inhibits barbed-end actin filament elongation physical 2 2 1 Reconstituted Complex, Biochemical Activity
RTC3 YHR087W Protein of unknown function involved in RNA metabolism genetic 2 1 1 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 Affinity Capture-MS
BDF1 YLR399C BET family transcriptional regulator genetic 1 1 1 Synthetic Growth Defect
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform physical 1 1 1 Affinity Capture-MS
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Reconstituted Complex
SAY1 YGR263C Sterol deacetylase physical 1 1 1 Affinity Capture-MS
SKN7 YHR206W Nuclear response regulator and transcription factor physical 1 1 1 Reconstituted Complex
CNA1 YLR433C Calcineurin A physical 1 1 1 Two-hybrid
PRP18 YGR006W Splicing factor and component of snRNP U5 physical 1 1 1 Two-hybrid
SLU7 YDR088C RNA splicing factor physical 1 1 1 Two-hybrid
SMD3 YLR147C Core Sm protein Sm D3 physical 1 1 1 Two-hybrid
MSL1 YIR009W U2B component of U2 snRNP physical 1 1 1 Two-hybrid
FAA4 YMR246W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p physical 1 1 1 Affinity Capture-MS
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis physical 1 1 1 Two-hybrid
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-MS
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes physical 1 1 1 Affinity Capture-MS
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex physical 1 1 1 Affinity Capture-MS
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK physical 1 1 1 Affinity Capture-MS
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-Western
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-Western
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
HCM1 YCR065W Forkhead transcription factor physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
RTS2 YOR077W Basic zinc-finger protein physical 1 1 1 Reconstituted Complex
JIP4 YDR475C Protein of unknown function physical 1 1 1 Reconstituted Complex
RCN2 YOR220W Protein of unknown function physical 1 1 1 Reconstituted Complex
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Reconstituted Complex
SRP40 YKR092C Nucleolar serine-rich protein physical 1 1 1 Reconstituted Complex
TFB6 YOR352W Subunit of TFIIH complex physical 1 1 1 Reconstituted Complex
INP52 YNL106C Polyphosphatidylinositol phosphatase physical 1 1 1 Reconstituted Complex
KIC1 YHR102W Protein kinase of the PAK/Ste20 family, required for cell integrity physical 1 1 1 Reconstituted Complex
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Reconstituted Complex
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 1 1 1 Reconstituted Complex
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 1 1 1 Reconstituted Complex
STB1 YNL309W Protein with role in regulation of MBF-specific transcription at Start physical 1 1 1 Reconstituted Complex
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade physical 1 1 1 Reconstituted Complex
YBR225W YBR225W Putative protein of unknown function physical 1 1 1 Reconstituted Complex
YPL247C YPL247C Putative protein of unknown function physical 1 1 1 Reconstituted Complex
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) physical 1 1 1 Biochemical Activity
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Dosage Rescue
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Dosage Rescue
VCX1 YDL128W Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity genetic 1 1 1 Dosage Rescue
STD1 YOR047C Protein involved in control of glucose-regulated gene expression genetic 1 1 1 Dosage Rescue
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Synthetic Growth Defect
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Negative Genetic
YKL075C YKL075C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
DOM34 YNL001W Protein that facilitates ribosomal subunit dissociation genetic 1 1 1 Negative Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
MSN4 YKL062W Stress-responsive transcriptional activator genetic 1 1 1 Negative Genetic
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress genetic 1 1 1 Negative Genetic
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Negative Genetic
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Positive Genetic
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 1 1 1 Positive Genetic
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase genetic 1 1 1 Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
VAM10 YOR068C Protein involved in vacuole morphogenesis genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HSP32 YPL280W Possible chaperone and cysteine protease genetic 1 1 1 Negative Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Positive Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Positive Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Positive Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Rescue
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 1 1 1 Positive Genetic
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p physical 1 1 1 Biochemical Activity
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Positive Genetic
ATC1 YDR184C Nuclear protein physical 1 1 1 Biochemical Activity
ATC1 YDR184C Nuclear protein genetic 1 1 1 Dosage Rescue
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter genetic 1 1 1 Dosage Rescue
AHC2 YCR082W Component of the ADA histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS