| FRS2 |
YFL022C |
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
3 |
2 |
2 |
Dosage Lethality, Dosage Lethality, Negative Genetic |
| TRM7 |
YBR061C |
2'-O-ribose methyltransferase |
genetic |
3 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| IAI11 |
YBL059W |
Putative mitochondrial protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| BAS1 |
YKR099W |
Myb-related transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRS2 |
YFL022C |
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILS1 |
YBL076C |
Cytoplasmic isoleucine-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GDS1 |
YOR355W |
Protein involved in histone H4 acetylation at ribosomal protein genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TSC13 |
YDL015C |
Enoyl reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ISR1 |
YPR106W |
Predicted protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| KCC4 |
YCL024W |
Protein kinase of the bud neck involved in the septin checkpoint |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| PKH2 |
YOL100W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| PKH3 |
YDR466W |
Protein kinase with similarity to mammalian PDK1 and yeast Pkh1p/Phk2p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GAS3 |
YMR215W |
Putative 1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC5 |
YDR166C |
Essential 107kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YCG1 |
YDR325W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI14 |
YJR013W |
Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP102 |
YKL154W |
Signal recognition particle (SRP) receptor beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NTR2 |
YKR022C |
Essential protein that forms a dimer with Ntr1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GSP1 |
YLR293C |
Ran GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI12 |
YMR281W |
ER membrane protein involved in the second step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM50 |
YPL063W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM1 |
YDR120C |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTO1 |
YGL236C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIA6 |
YIL006W |
Mitochondrial NAD+ transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKA1 |
YKL023W |
SKI complex-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP49 |
YKL167C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMH1 |
YLR309C |
Protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZRC1 |
YMR243C |
Vacuolar membrane zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET494 |
YNR045W |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM11 |
YOL124C |
Catalytic subunit of adoMet-dependent tRNA methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPM2 |
YOL141W |
AdoMet-dependent tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSC6 |
YOR354C |
Multicopy suppressor of HER2 involved in mitochondrial translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT10 |
YPL183C |
WD40 domain-containing protein involved in endosomal recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAR035C-A |
YAR035C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO11 |
YAR071W |
One of three repressible acid phosphatases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIC12 |
YBR262C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL085C-A |
YDL085C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS2 |
YDL107W |
Peripherally bound inner membrane protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RBS1 |
YDL189W |
Protein involved in assembly of the RNA Pol III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GRX3 |
YDR098C |
Glutathione-dependent oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSM28 |
YDR494W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIP1 |
YEL024W |
Ubiquinol-cytochrome-c reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET117 |
YER058W |
Assembly factor that couples heme a synthesis to complex IV assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF4632 |
YGL049C |
Translation initiation factor eIF4G and scaffold protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MUP1 |
YGR055W |
High affinity methionine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VSB1 |
YGR125W |
Vacuolar membrane protein required for uptake and storage of arginine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHB1 |
YGR132C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISY1 |
YJR050W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STR2 |
YJR130C |
Cystathionine gamma-synthase, converts cysteine into cystathionine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTA12 |
YMR089C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIP5 |
YMR140W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR155W |
YMR155W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL17 |
YNL252C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNT4 |
YNR059W |
Putative alpha-1,3-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM38 |
YOL027C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRM1 |
YOR201C |
Ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTA6 |
YPL074W |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXO70 |
YJL085W |
Subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AFG3 |
YER017C |
Mitochondrial inner membrane m-AAA protease component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP7 |
YKL016C |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN4 |
YMR138W |
GTP-binding protein involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALF1 |
YNL148C |
Alpha-tubulin folding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENV11 |
YGR071C |
Protein proposed to be involved in vacuolar functions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN2 |
YPL241C |
GTPase-activating protein (GAP) for Cin4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP14 |
YLR295C |
Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AEP3 |
YPL005W |
Peripheral mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACB1 |
YGR037C |
Acyl-CoA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCW22 |
YDR134C |
Cell wall protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX11 |
YPL132W |
Protein required for delivery of copper to Cox1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARO7 |
YPR060C |
Chorismate mutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDS1 |
YBR029C |
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD16 |
YEL029C |
Putative pyridoxal kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX16 |
YJL003W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPA10 |
YLR307C-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM8 |
YBR076W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
