Standard name Systematic name Name description Description
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase Catalytic subunit of 1,3-beta-glucan synthase; involved in formation of the inner layer of the spore wall; activity positively regulated by Rho1p and negatively by Smk1p; GSC2 has a paralog, FKS1, that arose from the whole genome duplication
Visualize the interactome of GSC2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data technical problem

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GSC2 2 2 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0005 (1,3-beta-glucan synthase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 16 6 12 Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Dosage Rescue, Synthetic Lethality, Synthetic Lethality, Dosage Rescue, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Rescue
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 2 2 2 Dosage Rescue, Dosage Growth Defect
ECM2 YBR065C Pre-mRNA splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
ATC1 YDR184C Nuclear protein genetic 2 1 2 Negative Genetic, Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases genetic 2 1 2 Negative Genetic, Negative Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
OCH1 YGL038C Mannosyltransferase of the cis-Golgi apparatus genetic 2 2 1 Dosage Rescue, Phenotypic Suppression
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 DNA to cDNA expression microarray evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT6 YGR116W Nucleosome remodeling protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response regulation 1 1 1 DNA to cDNA expression microarray evidence
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
MSS11 YMR164C Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Positive Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 1 1 1 Dosage Growth Defect
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network physical 1 1 1 PCA
COS111 YBR203W Protein required for antifungal drug ciclopirox olamine resistance genetic 1 1 1 Negative Genetic
GPN3 YLR243W Putative GTPase with a role in biogenesis of RNA pol II and polIII genetic 1 1 1 Negative Genetic
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p physical 1 1 1 Affinity Capture-MS
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Synthetic Lethality
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 1 1 1 Affinity Capture-MS
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Dosage Growth Defect
EPO1 YMR124W Protein involved in septin-ER tethering physical 1 1 1 PCA
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-MS
SMK1 YPR054W Middle sporulation-specific mitogen-activated protein kinase (MAPK) physical 1 1 1 Affinity Capture-Western
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 1 1 1 Co-fractionation
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 1 1 1 Co-fractionation
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
KIN3 YAR018C Nonessential serine/threonine protein kinase physical 1 1 1 Affinity Capture-MS
PTP1 YDL230W Phosphotyrosine-specific protein phosphatase physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
HTA1 YDR225W Histone H2A physical 1 1 1 Affinity Capture-MS
HTA2 YBL003C Histone H2A physical 1 1 1 Affinity Capture-MS
KEL1 YHR158C Protein required for proper cell fusion and cell morphology physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER physical 1 1 1 PCA
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall physical 1 1 1 Affinity Capture-MS
SCW4 YGR279C Cell wall protein with similarity to glucanases genetic 1 1 1 Phenotypic Enhancement
SCW10 YMR305C Cell wall protein with similarity to glucanases genetic 1 1 1 Phenotypic Enhancement
LRG1 YDL240W GTPase-activating protein (GAP) genetic 1 1 1 Synthetic Rescue
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
MCP1 YOR228C Mitochondrial protein of unknown function involved in lipid homeostas genetic 1 1 1 Negative Genetic
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Negative Genetic
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Dosage Rescue
QRI7 YDL104C Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Positive Genetic
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Positive Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
PCA1 YBR295W Cadmium transporting P-type ATPase genetic 1 1 1 Negative Genetic
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
YPS7 YDR349C Putative GPI-anchored aspartic protease genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Negative Genetic
RSM7 YJR113C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
YKR075C YKR075C Protein of unknown function genetic 1 1 1 Negative Genetic
YLL054C YLL054C Putative protein of unknown function with similarity to Pip2p genetic 1 1 1 Negative Genetic
NHA1 YLR138W Na+/H+ antiporter genetic 1 1 1 Negative Genetic
LUG1 YLR352W Protein of unknown function with similarity to F-box proteins genetic 1 1 1 Negative Genetic
SMA2 YML066C Meiosis-specific prospore membrane protein genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
MET7 YOR241W Folylpolyglutamate synthetase genetic 1 1 1 Negative Genetic
YOR381W-A YOR381W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPO19 YPL130W Meiosis-specific prospore protein genetic 1 1 1 Negative Genetic
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Dosage Rescue
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
GCG1 YER163C Gamma-glutamyl cyclotransferase genetic 1 1 1 Negative Genetic
FKS3 YMR306W Protein involved in spore wall assembly genetic 1 1 1 Synthetic Lethality
CMC2 YBL059C-A Protein involved in respiratory chain complex assembly or maintenance genetic 1 1 1 Negative Genetic