SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
genetic |
6 |
3 |
5 |
Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement |
SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
physical |
6 |
2 |
5 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
4 |
2 |
1 |
Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
CAP2 |
YIL034C |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) |
physical |
4 |
2 |
1 |
Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
3 |
3 |
3 |
Synthetic Rescue, Phenotypic Suppression, Dosage Growth Defect |
STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
genetic |
3 |
3 |
3 |
Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Phenotypic Suppression, Negative Genetic |
CDC42 |
YLR229C |
Small rho-like GTPase |
physical |
3 |
3 |
1 |
Two-hybrid, Affinity Capture-Western, Reconstituted Complex |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
SVL3 |
YPL032C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MNT2 |
YGL257C |
Mannosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
2 |
2 |
1 |
Synthetic Lethality, Synthetic Rescue |
FLO11 |
YIR019C |
GPI-anchored cell surface glycoprotein (flocculin) |
genetic |
2 |
2 |
1 |
Phenotypic Enhancement, Phenotypic Suppression |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TEC1 |
YBR083W |
Transcription factor targeting filamentation genes and Ty1 expression |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SWI6 |
YLR182W |
Transcription cofactor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BEM1 |
YBR200W |
Protein containing SH3-domains |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Two-hybrid |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HHF2 |
YNL030W |
Histone H4 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MAM33 |
YIL070C |
Acidic protein of the mitochondrial matrix |
physical |
1 |
1 |
1 |
Reconstituted Complex |
GPT2 |
YKR067W |
Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIP1 |
YMR092C |
Actin cortical patch component |
physical |
1 |
1 |
1 |
Reconstituted Complex |
GPP2 |
YER062C |
DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ERG20 |
YJL167W |
Farnesyl pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
EMI2 |
YDR516C |
Hexokinase expressed during growth with low glucose levels |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CIA1 |
YDR267C |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
physical |
1 |
1 |
1 |
Reconstituted Complex |
MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
physical |
1 |
1 |
1 |
Two-hybrid |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
physical |
1 |
1 |
1 |
Two-hybrid |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
physical |
1 |
1 |
1 |
Reconstituted Complex |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
physical |
1 |
1 |
1 |
Two-hybrid |
MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
physical |
1 |
1 |
1 |
Two-hybrid |
NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
physical |
1 |
1 |
1 |
Two-hybrid |
NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
RCF3 |
YBR255C-A |
Mitochondrial inner membrane protein |
physical |
1 |
1 |
1 |
PCA |
TYC1 |
YBR296C-A |
Inhibitor of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
physical |
1 |
1 |
1 |
PCA |
UIP3 |
YAR027W |
Putative integral membrane protein of unknown function |
physical |
1 |
1 |
1 |
PCA |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
STE11 |
YLR362W |
Signal transducing MEK kinase |
physical |
1 |
1 |
1 |
PCA |
STE11 |
YLR362W |
Signal transducing MEK kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RIO1 |
YOR119C |
Serine kinase involved in cell cycle regulation and rDNA integrity |
physical |
1 |
1 |
1 |
Two-hybrid |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
QCR6 |
YFR033C |
Subunit 6 of the ubiquinol cytochrome-c reductase complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SKI8 |
YGL213C |
Ski complex component and WD-repeat protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SSD1 |
YDR293C |
Translational repressor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PMT4 |
YJR143C |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
YFH1 |
YDL120W |
Mitochondrial matrix iron chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PTP2 |
YOR208W |
Phosphotyrosine-specific phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PTP3 |
YER075C |
Phosphotyrosine-specific protein phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Haploinsufficiency |
VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Haploinsufficiency |
PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSR1 |
YGR152C |
Ras-type GTPase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOM6 |
YOR045W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUF1 |
YOR187W |
Mitochondrial translation elongation factor Tu (EF-Tu) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GIC1 |
YHR061C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HKR1 |
YDR420W |
Mucin family member that functions as an osmosensor in the HOG pathway |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
GIC2 |
YDR309C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
1 |
1 |
1 |
Dosage Rescue |
HRI1 |
YLR301W |
Protein of unknown function that interacts with Sec72p and Hrr25p |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
CAN1 |
YEL063C |
Plasma membrane arginine permease |
physical |
1 |
1 |
1 |
PCA |
MIG2 |
YGL209W |
Zinc finger transcriptional repressor |
physical |
1 |
1 |
1 |
Two-hybrid |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRD1 |
YEL047C |
Soluble fumarate reductase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC27 |
YNL100W |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL32 |
YBR299W |
Maltase (alpha-D-glucosidase) |
physical |
1 |
1 |
1 |
Reconstituted Complex |