Standard name Systematic name Name description Description
MYO3 YKL129C One of two type I myosins One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; MYO3 has a paralog, MYO5, that arose from the whole genome duplication
Visualize the interactome of MYO3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 156

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.076 0.183 0.220
Cell Periphery 0.144 0.151 0.079
Cort. Patches 0.520 0.659 0.693
Cytoplasm 0.220 0.168 0.159
Endosome 0.097 NaN NaN
Golgi 0.069 NaN NaN
Peroxisome 0.069 0.072 0.097
SpindlePole 0.051 NaN NaN
ER NaN 0.115 NaN
Mito NaN 0.075 0.108
Budsite NaN NaN 0.061

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, actin 155

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MYO3 0 0 1 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MYO5 YMR109W One of two type I myosin motors genetic 12 4 11 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein physical 10 3 6 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid
LAS17 YOR181W Actin assembly factor physical 8 4 6 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Protein-peptide, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 5 2 3 Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid
LAS17 YOR181W Actin assembly factor genetic 3 3 3 Synthetic Lethality, Dosage Rescue, Phenotypic Suppression
CMD1 YBR109C Calmodulin physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Two-hybrid
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway physical 3 2 3 Two-hybrid, Two-hybrid, Affinity Capture-MS
MYO5 YMR109W One of two type I myosin motors physical 3 2 3 Two-hybrid, Affinity Capture-MS, Two-hybrid
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 3 1 3 Two-hybrid, Two-hybrid, Two-hybrid
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain physical 3 2 2 Affinity Capture-Western, Two-hybrid, Two-hybrid
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 3 3 1 Two-hybrid, Affinity Capture-Western, Reconstituted Complex
ARC19 YKL013C Subunit of the ARP2/3 complex physical 3 2 1 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid
ARC40 YBR234C Subunit of the ARP2/3 complex physical 3 2 1 Affinity Capture-Western, Affinity Capture-Western, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 2 1 2 Negative Genetic, Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
SRL1 YOR247W Mannoprotein that exhibits a tight association with the cell wall physical 2 1 2 Two-hybrid, Two-hybrid
TMA17 YDL110C Regulatory gamma subunit of fatty acid synthase (FAS) genetic 2 1 2 Negative Genetic, Negative Genetic
BNR1 YIL159W Formin physical 2 1 2 Two-hybrid, Two-hybrid
BNI1 YNL271C Formin physical 2 2 1 Affinity Capture-Western, Two-hybrid
CLC1 YGR167W Clathrin light chain genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARP2 YDL029W Essential component of the Arp2/3 complex physical 1 1 1 Affinity Capture-Western
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Synthetic Lethality
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Biochemical Activity
BNI1 YNL271C Formin genetic 1 1 1 Phenotypic Enhancement
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
END3 YNL084C EH domain-containing protein involved in endocytosis physical 1 1 1 Two-hybrid
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPS28 YDR337W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
GPM1 YKL152C Tetrameric phosphoglycerate mutase physical 1 1 1 Two-hybrid
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
BGL2 YGR282C Endo-beta-1,3-glucanase genetic 1 1 1 Negative Genetic
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization physical 1 1 1 Two-hybrid
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization genetic 1 1 1 Synthetic Lethality
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-MS
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
CNB1 YKL190W Calcineurin B genetic 1 1 1 Phenotypic Suppression
ATG42 YBR139W Vacuolar serine-type carboxypeptidase genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization physical 1 1 1 Two-hybrid
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
IKS1 YJL057C Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
KAR9 YPL269W Spindle positioning factor genetic 1 1 1 Negative Genetic
MTH1 YDR277C Negative regulator of the glucose-sensing signal transduction pathway physical 1 1 1 Two-hybrid
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Two-hybrid
ROX3 YBL093C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Two-hybrid
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 1 1 1 Biochemical Activity
SRP21 YKL122C Subunit of the signal recognition particle (SRP) physical 1 1 1 Affinity Capture-MS
YGL242C YGL242C Protein of unknown function physical 1 1 1 Affinity Capture-MS
RRP43 YCR035C Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
RRP4 YHR069C Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
YSC84 YHR016C Actin-binding protein physical 1 1 1 Two-hybrid
OSH2 YDL019C Member of an oxysterol-binding protein family with seven members physical 1 1 1 Two-hybrid
OSH2 YDL019C Member of an oxysterol-binding protein family with seven members genetic 1 1 1 Phenotypic Suppression
SAP1 YER047C Putative ATPase of the AAA family physical 1 1 1 Two-hybrid
SER1 YOR184W 3-phosphoserine aminotransferase physical 1 1 1 Two-hybrid
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme physical 1 1 1 Two-hybrid
STD1 YOR047C Protein involved in control of glucose-regulated gene expression physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
MYO3 YKL129C One of two type I myosins physical 1 1 1 Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
UBP5 YER144C Putative ubiquitin-specific protease genetic 1 1 1 Dosage Rescue
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Negative Genetic
YSR3 YKR053C Dihydrosphingosine 1-phosphate phosphatase genetic 1 1 1 Negative Genetic
TPK3 YKL166C cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 1 1 1 Positive Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF genetic 1 1 1 Negative Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Negative Genetic
PMT4 YJR143C Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Negative Genetic
YLR053C YLR053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs genetic 1 1 1 Negative Genetic
RPS18B YML026C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 1 1 1 Negative Genetic
USA1 YML029W Scaffold subunit of the Hrd1p ubiquitin ligase genetic 1 1 1 Negative Genetic
YMR242W-A YMR242W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Dosage Rescue
OSH3 YHR073W Member of an oxysterol-binding protein family genetic 1 1 1 Phenotypic Suppression
BNR1 YIL159W Formin genetic 1 1 1 Phenotypic Enhancement
ERG25 YGR060W C-4 methyl sterol oxidase genetic 1 1 1 Negative Genetic
MET31 YPL038W Zinc-finger DNA-binding transcription factor physical 1 1 1 Two-hybrid
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 1 1 1 Biochemical Activity
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Phenotypic Enhancement
MET1 YKR069W S-adenosyl-L-methionine uroporphyrinogen III transmethylase physical 1 1 1 Two-hybrid
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
EMA35 YCR100C Protein involved in protein sorting genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Dosage Rescue
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality
FSH2 YMR222C Putative serine hydrolase that localizes to the cytoplasm genetic 1 1 1 Negative Genetic