Standard name Systematic name Name description Description
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; regulated by phosphorylation and ubiquitination; likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity; necessary for oxidant and ramped heat stress-induced cell death; ortholog of mammalian RAC1
Visualize the interactome of RHO5
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1 212

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.511 0.853 0.758
Vac/Vac Memb 0.556 0.211 0.403
Nucleus NaN 0.110 0.081

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 2180

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RHO5 0 0 0 1 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ATG21 YPL100W Phosphoinositide binding protein physical 3 2 1 PCA, PCA, Two-hybrid
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 2 1 Phenotypic Enhancement, Synthetic Rescue
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 2 2 1 Synthetic Rescue, Dosage Growth Defect
NPR1 YNL183C Protein kinase genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 RNA-sequencing evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN4 YKL062W Stress-responsive transcriptional activator regulation 1 1 1 RNA-sequencing evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHD1 YKL043W Transcriptional activator that enhances pseudohyphal growth regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Synthetic Rescue
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Synthetic Rescue
CDC10 YCR002C Component of the septin ring, required for cytokinesis physical 1 1 1 PCA
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Synthetic Rescue
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 1 1 1 PCA
CYS4 YGR155W Cystathionine beta-synthase physical 1 1 1 PCA
CYS4 YGR155W Cystathionine beta-synthase genetic 1 1 1 Synthetic Rescue
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
GLY1 YEL046C Threonine aldolase physical 1 1 1 PCA
KGD1 YIL125W Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex genetic 1 1 1 Synthetic Rescue
KIN3 YAR018C Nonessential serine/threonine protein kinase genetic 1 1 1 Synthetic Rescue
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 PCA
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 1 1 1 PCA
HER1 YOR227W Protein of unknown function genetic 1 1 1 Synthetic Rescue
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 PCA
GPM1 YKL152C Tetrameric phosphoglycerate mutase physical 1 1 1 PCA
MSL1 YIR009W U2B component of U2 snRNP genetic 1 1 1 Synthetic Rescue
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Rescue
LSP1 YPL004C Eisosome core component physical 1 1 1 PCA
LSP1 YPL004C Eisosome core component genetic 1 1 1 Synthetic Rescue
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase physical 1 1 1 PCA
ARF1 YDL192W ADP-ribosylation factor genetic 1 1 1 Synthetic Rescue
AHP1 YLR109W Thiol-specific peroxiredoxin physical 1 1 1 PCA
CNB1 YKL190W Calcineurin B genetic 1 1 1 Synthetic Rescue
TRR1 YDR353W Cytoplasmic thioredoxin reductase physical 1 1 1 Affinity Capture-MS
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) physical 1 1 1 PCA
STE50 YCL032W Adaptor protein for various signaling pathways physical 1 1 1 Reconstituted Complex
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Dosage Growth Defect
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 1 1 1 PCA
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 1 1 1 Synthetic Rescue
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 PCA
RTN1 YDR233C Reticulon protein physical 1 1 1 PCA
RTN1 YDR233C Reticulon protein genetic 1 1 1 Synthetic Rescue
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein physical 1 1 1 PCA
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase physical 1 1 1 PCA
STE24 YJR117W Highly conserved zinc metalloprotease physical 1 1 1 PCA
STE24 YJR117W Highly conserved zinc metalloprotease genetic 1 1 1 Synthetic Rescue
SUR7 YML052W Plasma membrane protein, component of eisosomes physical 1 1 1 PCA
SUR7 YML052W Plasma membrane protein, component of eisosomes genetic 1 1 1 Synthetic Rescue
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 physical 1 1 1 PCA
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 PCA
TMA19 YKL056C Protein that associates with ribosomes physical 1 1 1 PCA
TMA19 YKL056C Protein that associates with ribosomes genetic 1 1 1 Synthetic Rescue
TPI1 YDR050C Triose phosphate isomerase, abundant glycolytic enzyme physical 1 1 1 PCA
TPO4 YOR273C Polyamine transporter of the major facilitator superfamily physical 1 1 1 PCA
VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter physical 1 1 1 PCA
VMA10 YHR039C-A Subunit G of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 PCA
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) physical 1 1 1 PCA
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Proximity Label-MS
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Synthetic Rescue
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
RTC6 YPL183W-A Protein involved in translation genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
TDP1 YBR223C Tyrosyl-DNA phosphodiesterase I genetic 1 1 1 Synthetic Lethality
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Lethality
RPL41B YDL133C-A Ribosomal 60S subunit protein L41B genetic 1 1 1 Synthetic Rescue
YGL159W YGL159W Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
YOX1 YML027W Homeobox transcriptional repressor genetic 1 1 1 Synthetic Rescue
YLR001C YLR001C Putative protein of unknown function genetic 1 1 1 Synthetic Rescue
SPO1 YNL012W Meiosis-specific prospore protein genetic 1 1 1 Synthetic Rescue
YLR036C YLR036C Putative protein predicted to have transmembrane domains genetic 1 1 1 Synthetic Rescue
SLI1 YGR212W N-acetyltransferase genetic 1 1 1 Synthetic Rescue
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Synthetic Rescue
RIB1 YBL033C GTP cyclohydrolase II genetic 1 1 1 Synthetic Rescue
RPL16A YIL133C Ribosomal 60S subunit protein L16A genetic 1 1 1 Synthetic Rescue
YJR056C YJR056C Protein of unknown function genetic 1 1 1 Synthetic Rescue
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p genetic 1 1 1 Synthetic Rescue
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 1 1 1 Synthetic Rescue
RMA1 YKL132C Putative dihydrofolate synthetase genetic 1 1 1 Synthetic Rescue
UIP3 YAR027W Putative integral membrane protein of unknown function genetic 1 1 1 Synthetic Rescue
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Synthetic Rescue
SUC2 YIL162W Invertase genetic 1 1 1 Synthetic Rescue
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Synthetic Rescue
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) genetic 1 1 1 Synthetic Rescue
AMF1 YOR378W Low affinity NH4+ transporter genetic 1 1 1 Synthetic Rescue
RAS1 YOR101W GTPase involved in G-protein signaling in adenylate cyclase activation genetic 1 1 1 Synthetic Rescue
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division physical 1 1 1 PCA
DBF20 YPR111W Ser/Thr kinase involved in late nuclear division genetic 1 1 1 Synthetic Rescue
MLH3 YPL164C Protein involved in DNA mismatch repair and meiotic recombination physical 1 1 1 Affinity Capture-MS
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Dosage Rescue
GPA2 YER020W Nucleotide binding alpha subunit of the heterotrimeric G protein genetic 1 1 1 Synthetic Growth Defect
PDC5 YLR134W Minor isoform of pyruvate decarboxylase physical 1 1 1 PCA
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Synthetic Rescue
ERG6 YML008C Delta(24)-sterol C-methyltransferase physical 1 1 1 PCA
GAL7 YBR018C Galactose-1-phosphate uridyl transferase genetic 1 1 1 Synthetic Rescue
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 1 1 1 Phenotypic Suppression
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 1 1 1 Synthetic Rescue
IRA1 YBR140C GTPase-activating protein genetic 1 1 1 Synthetic Rescue
HXT5 YHR096C Hexose transporter with moderate affinity for glucose genetic 1 1 1 Synthetic Rescue
NDE1 YMR145C Mitochondrial external NADH dehydrogenase genetic 1 1 1 Negative Genetic
POL4 YCR014C DNA polymerase IV physical 1 1 1 Affinity Capture-MS
PML1 YLR016C Subunit of the RES complex genetic 1 1 1 Synthetic Rescue
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Phenotypic Suppression
MNS1 YJR131W Alpha-1,2-mannosidase genetic 1 1 1 Synthetic Rescue
CRP1 YHR146W Protein that binds to cruciform DNA structures physical 1 1 1 PCA
RGT1 YKL038W Glucose-responsive transcription factor genetic 1 1 1 Synthetic Rescue
HXK2 YGL253W Hexokinase isoenzyme 2 physical 1 1 1 PCA
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Synthetic Rescue
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
NMD2 YHR077C Protein involved in the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Synthetic Rescue
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
MSO1 YNR049C Lipid-interacting protein in SNARE complex assembly machinery genetic 1 1 1 Synthetic Rescue
BUD6 YLR319C Actin- and formin-interacting protein genetic 1 1 1 Negative Genetic
DSE1 YER124C Daughter cell-specific protein genetic 1 1 1 Synthetic Rescue
CDC19 YAL038W Pyruvate kinase physical 1 1 1 PCA
MEI4 YER044C-A Meiosis-specific protein involved in forming DSBs genetic 1 1 1 Synthetic Rescue
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 PCA
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Synthetic Growth Defect
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p physical 1 1 1 Two-hybrid
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p genetic 1 1 1 Dosage Rescue
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
MET1 YKR069W S-adenosyl-L-methionine uroporphyrinogen III transmethylase genetic 1 1 1 Synthetic Rescue
CAT2 YML042W Carnitine acetyl-CoA transferase genetic 1 1 1 Synthetic Rescue
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine physical 1 1 1 PCA
NCE102 YPR149W Protein of unknown function physical 1 1 1 PCA
NCE102 YPR149W Protein of unknown function genetic 1 1 1 Synthetic Rescue
GLO2 YDR272W Cytoplasmic glyoxalase II genetic 1 1 1 Synthetic Rescue
BNA1 YJR025C 3-hydroxyanthranilic acid dioxygenase genetic 1 1 1 Synthetic Rescue
ACB1 YGR037C Acyl-CoA-binding protein physical 1 1 1 PCA
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Synthetic Rescue
ALD6 YPL061W Cytosolic aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
ATG21 YPL100W Phosphoinositide binding protein genetic 1 1 1 Synthetic Rescue
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
MRX3 YBL095W Protein that associates with mitochondrial ribosome genetic 1 1 1 Synthetic Rescue
KTR1 YOR099W Alpha-1,2-mannosyltransferase genetic 1 1 1 Synthetic Rescue
NPR1 YNL183C Protein kinase physical 1 1 1 Biochemical Activity
HXT3 YDR345C Low affinity glucose transporter of the major facilitator superfamily physical 1 1 1 PCA
HXT3 YDR345C Low affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Synthetic Rescue
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily physical 1 1 1 PCA
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Synthetic Rescue
ITR1 YDR497C Myo-inositol transporter physical 1 1 1 PCA
BAP2 YBR068C High-affinity leucine permease physical 1 1 1 PCA
MSP1 YGR028W Highly-conserved N-terminally anchored AAA-ATPase physical 1 1 1 PCA
MSP1 YGR028W Highly-conserved N-terminally anchored AAA-ATPase genetic 1 1 1 Synthetic Rescue
ERG3 YLR056W C-5 sterol desaturase genetic 1 1 1 Positive Genetic
DSE2 YHR143W Daughter cell-specific secreted protein with similarity to glucanases genetic 1 1 1 Synthetic Rescue
MPC2 YHR162W Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Negative Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Synthetic Rescue
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
HIM1 YDR317W Protein of unknown function involved in DNA repair genetic 1 1 1 Synthetic Rescue
AIM19 YIL087C Protein of unknown function genetic 1 1 1 Synthetic Rescue
PMP3 YDR276C Small plasma membrane protein physical 1 1 1 PCA
CWP1 YKL096W Cell wall mannoprotein that localizes to birth scars of daughter cells physical 1 1 1 PCA
CWP1 YKL096W Cell wall mannoprotein that localizes to birth scars of daughter cells genetic 1 1 1 Synthetic Rescue