Standard name Systematic name Name description Description
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; binds to ER-derived membranes and targets mRNAs to cortical ER
Visualize the interactome of SHE2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G2 94

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.985 0.97 0.964

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 4070

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SHE2 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex physical 21 6 17 Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, PCA, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Co-crystal Structure, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex physical 18 2 17 Affinity Capture-RNA, Protein-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Protein-RNA, Protein-RNA, Protein-RNA, Affinity Capture-RNA, Protein-RNA, Affinity Capture-RNA, Protein-RNA, Protein-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Protein-RNA, Protein-RNA, Protein-RNA, Protein-RNA
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos physical 13 6 10 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-MS, Co-fractionation, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 6 4 4 Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure, Co-crystal Structure, Reconstituted Complex, Affinity Capture-Western
LOC1 YFR001W Nucleolar protein involved in the asymmetric localization of ASH1 mRNA physical 6 3 3 Affinity Capture-Western, Co-localization, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex
PUF6 YDR496C Pumilio-homology domain protein physical 5 3 3 Affinity Capture-Western, Affinity Capture-Western, Co-localization, Reconstituted Complex, Affinity Capture-Western
SRP1 YNL189W Karyopherin alpha homolog physical 4 2 2 Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex
SEC61 YLR378C Conserved ER protein translocation channel physical 3 3 2 Co-fractionation, Reconstituted Complex, Affinity Capture-MS
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering physical 2 2 2 Protein-RNA, Affinity Capture-RNA
UBX6 YJL048C UBX (ubiquitin regulatory X) domain-containing protein physical 2 1 2 Two-hybrid, Two-hybrid
NCE101 YJL205C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
MUD1 YBR119W U1 snRNP A protein physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase physical 1 1 1 Affinity Capture-RNA
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
CDC42 YLR229C Small rho-like GTPase physical 1 1 1 Affinity Capture-RNA
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-RNA
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-MS
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome physical 1 1 1 Two-hybrid
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Negative Genetic
BNI1 YNL271C Formin physical 1 1 1 PCA
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly physical 1 1 1 Affinity Capture-RNA
FAP1 YNL023C Protein that binds to Fpr1p physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
LCB1 YMR296C Component of serine palmitoyltransferase physical 1 1 1 Affinity Capture-RNA
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex physical 1 1 1 Affinity Capture-RNA
ADE3 YGR204W Cytoplasmic trifunctional enzyme physical 1 1 1 Affinity Capture-RNA
SLM1 YIL105C Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p physical 1 1 1 Two-hybrid
SRO7 YPR032W Effector of Rab GTPase Sec4p physical 1 1 1 Affinity Capture-RNA
SRO77 YBL106C Protein with roles in exocytosis and cation homeostasis physical 1 1 1 Affinity Capture-RNA
SRL1 YOR247W Mannoprotein that exhibits a tight association with the cell wall physical 1 1 1 Affinity Capture-RNA
YSP2 YDR326C Sterol-binding protein physical 1 1 1 Affinity Capture-RNA
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway physical 1 1 1 Affinity Capture-RNA
SUI1 YNL244C Translation initiation factor eIF1 physical 1 1 1 Affinity Capture-RNA
TCB2 YNL087W ER protein involved in ER-plasma membrane tethering physical 1 1 1 Affinity Capture-RNA
TAM41 YGR046W Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) physical 1 1 1 Affinity Capture-RNA
TKL1 YPR074C Transketolase physical 1 1 1 Affinity Capture-RNA
YEF3 YLR249W Translation elongation factor 3 physical 1 1 1 Affinity Capture-RNA
SUN4 YNL066W Cell wall protein related to glucanases localized in birth scars physical 1 1 1 Affinity Capture-RNA
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B physical 1 1 1 Affinity Capture-RNA
YLR179C YLR179C Protein of unknown function with similarity to Tfs1p physical 1 1 1 Affinity Capture-RNA
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 1 1 1 Affinity Capture-RNA
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
STE7 YDL159W Signal transducing MAP kinase kinase physical 1 1 1 Affinity Capture-RNA
SUC2 YIL162W Invertase physical 1 1 1 Affinity Capture-RNA
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein genetic 1 1 1 Negative Genetic
YSR3 YKR053C Dihydrosphingosine 1-phosphate phosphatase genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
YIL102C YIL102C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
SEC3 YER008C Subunit of the exocyst complex physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase physical 1 1 1 Affinity Capture-RNA
RHO5 YNL180C Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Synthetic Rescue
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein genetic 1 1 1 Negative Genetic
MDM30 YLR368W F-box component of an SCF ubiquitin protein ligase complex genetic 1 1 1 Negative Genetic
IMD4 YML056C Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
NTF2 YER009W Nuclear envelope protein physical 1 1 1 Affinity Capture-RNA
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 1 1 1 Affinity Capture-RNA
INA1 YLR413W Protein of unknown function physical 1 1 1 Affinity Capture-RNA
SEC4 YFL005W Rab family GTPase physical 1 1 1 Affinity Capture-RNA
CLB2 YPR119W B-type cyclin involved in cell cycle progression physical 1 1 1 Affinity Capture-RNA
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Affinity Capture-RNA
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase physical 1 1 1 Affinity Capture-RNA
CYS3 YAL012W Cystathionine gamma-lyase physical 1 1 1 Affinity Capture-RNA
KKQ8 YKL168C Putative serine/threonine protein kinase with unknown cellular role physical 1 1 1 Reconstituted Complex
ATP20 YPR020W Subunit g of the mitochondrial F1F0 ATP synthase physical 1 1 1 Two-hybrid
LPP1 YDR503C Lipid phosphate phosphatase physical 1 1 1 Two-hybrid
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Positive Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane physical 1 1 1 Affinity Capture-RNA
IKS1 YJL057C Protein kinase of unknown cellular role physical 1 1 1 Reconstituted Complex
IKS1 YJL057C Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-RNA
KAR3 YPR141C Minus-end-directed microtubule motor physical 1 1 1 Affinity Capture-RNA
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles physical 1 1 1 Affinity Capture-RNA
BUD8 YLR353W Protein involved in bud-site selection physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 1 1 1 Negative Genetic
MID2 YLR332W O-glycosylated plasma membrane protein physical 1 1 1 Affinity Capture-RNA
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane physical 1 1 1 Affinity Capture-RNA
AUS1 YOR011W Plasma membrane sterol transporter of the ATP-binding cassette family physical 1 1 1 Protein-peptide
CPS1 YJL172W Vacuolar carboxypeptidase S physical 1 1 1 Affinity Capture-RNA
ERG2 YMR202W C-8 sterol isomerase physical 1 1 1 Affinity Capture-RNA
FRE3 YOR381W Ferric reductase genetic 1 1 1 Negative Genetic
ACB1 YGR037C Acyl-CoA-binding protein physical 1 1 1 Affinity Capture-RNA
PSD2 YGR170W Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes genetic 1 1 1 Negative Genetic
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
IRC8 YJL051W Bud tip localized protein of unknown function physical 1 1 1 Affinity Capture-RNA
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
FRE8 YLR047C Protein with sequence similarity to iron/copper reductases genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
PUF2 YPR042C PUF family mRNA-binding protein genetic 1 1 1 Phenotypic Enhancement
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins physical 1 1 1 Affinity Capture-RNA
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Positive Genetic
PRY2 YKR013W Sterol binding protein involved in the export of acetylated sterols physical 1 1 1 Affinity Capture-RNA
AIM34 YMR003W Protein of unknown function physical 1 1 1 Affinity Capture-RNA
SCY1 YGL083W Putative kinase physical 1 1 1 Affinity Capture-RNA
CIS3 YJL158C Mannose-containing glycoprotein constituent of the cell wall physical 1 1 1 Affinity Capture-RNA
PRY1 YJL079C Lipid binding protein physical 1 1 1 Affinity Capture-RNA
MIM1 YOL026C Mitochondrial protein required for outer membrane protein import physical 1 1 1 Affinity Capture-Western
HLJ1 YMR161W Co-chaperone for Hsp40p genetic 1 1 1 Negative Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Positive Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Negative Genetic