Standard name Systematic name Name description Description
WTM1 YOR230W Transcriptional modulator Transcriptional modulator; involved in regulation of meiosis, silencing, and expression of RNR genes; acts as a nuclear anchor to retain the ribonucleotide reductase small subunit heterodimer, Rnr2p-Rnr4p, in the nucleus when cells are not in S phase; contains WD repeats
Visualize the interactome of WTM1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 172

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.351 0.20 0.155
Nucleus 0.892 0.92 0.915

GFP localization & abundance

GFP localization GFP abundance
nucleus 7750

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
WTM1 3 2 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit physical 8 4 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Co-localization, Affinity Capture-Western, Affinity Capture-Western
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit physical 6 5 4 Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Co-localization, Two-hybrid
WTM2 YOR229W Transcriptional modulator physical 6 3 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid
FKH1 YIL131C Forkhead family transcription factor regulation 5 3 5 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 5 3 5 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 4 2 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
KAP122 YGL016W Karyopherin beta physical 3 2 1 Co-localization, Affinity Capture-Western, Affinity Capture-Western
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
DIF1 YLR437C Protein that regulates nuclear import of Rnr2p and Rnr4p genetic 2 2 2 Dosage Rescue, Phenotypic Enhancement
WTM1 YOR230W Transcriptional modulator physical 2 2 1 Affinity Capture-Western, Two-hybrid
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 DNA to cDNA expression microarray evidence
MET32 YDR253C Zinc-finger DNA-binding transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MET4 YNL103W Leucine-zipper transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 DNA to cDNA expression microarray evidence
CYC8 YBR112C General transcriptional co-repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PGK1 YCR012W 3-phosphoglycerate kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ACO1 YLR304C Aconitase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BUD6 YLR319C Actin- and formin-interacting protein regulation 1 1 1 DNA to cDNA expression microarray evidence
GNP1 YDR508C Broad specificity amino acid permease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NKP2 YLR315W Central kinetochore protein and subunit of the Ctf19 complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TRK2 YKR050W Component of the Trk1p-Trk2p potassium transport system regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PCL2 YDL127W Cyclin, interacts with cyclin-dependent kinase Pho85p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MDH2 YOL126C Cytoplasmic malate dehydrogenase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MUP1 YGR055W High affinity methionine permease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CTH1 YDR151C mRNA binding protein, member of the CCCH zinc finger family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NVJ1 YHR195W Nuclear envelope protein regulation 1 1 1 DNA to cDNA expression microarray evidence
ATC1 YDR184C Nuclear protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PTP2 YOR208W Phosphotyrosine-specific phosphatase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ATO3 YDR384C Plasma membrane protein, putative ammonium transporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GAT4 YIR013C Protein containing GATA family zinc finger motifs regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PMP2 YEL017C-A Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
OPT1 YJL212C Proton-coupled oligopeptide transporter of the plasma membrane regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DPI8 YJL133C-A Putative mitochondrial protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR412C-A YLR412C-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YIL055C YIL055C Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YBR225W YBR225W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
SRL3 YKR091W Repressor of transcription at Start regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPS0A YGR214W Ribosomal 40S subunit protein S0A regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPL20A YMR242C Ribosomal 60S subunit protein L20A regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPL34B YIL052C Ribosomal 60S subunit protein L34B regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RSA4 YCR072C Ribosomal large subunit (60S) assembly factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PRP18 YGR006W Splicing factor and component of snRNP U5 regulation 1 1 1 chromatin immunoprecipitation-chip evidence
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ELG1 YOR144C Subunit of an alternative replication factor C complex regulation 1 1 1 DNA to cDNA expression microarray evidence
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex regulation 1 1 1 DNA to cDNA expression microarray evidence
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PDR8 YLR266C Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HAL9 YOL089C Putative transcription factor containing a zinc finger regulation 1 1 1 DNA to cDNA expression microarray evidence
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis regulation 1 1 1 DNA to cDNA expression microarray evidence
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component physical 1 1 1 Affinity Capture-MS
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
HHF1 YBR009C Histone H4 genetic 1 1 1 Negative Genetic
AEP2 YMR282C Mitochondrial protein genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Phenotypic Enhancement
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
HRK1 YOR267C Protein kinase genetic 1 1 1 Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
MLP1 YKR095W Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
BNA3 YJL060W Kynurenine aminotransferase genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Positive Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Positive Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
YHM2 YMR241W Citrate and oxoglutarate carrier protein genetic 1 1 1 Negative Genetic
YOL057W YOL057W Dipeptidyl-peptidase III genetic 1 1 1 Negative Genetic
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins physical 1 1 1 Affinity Capture-MS
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
SEN15 YMR059W Subunit of the tRNA splicing endonuclease physical 1 1 1 Affinity Capture-MS
HHT1 YBR010W Histone H3 genetic 1 1 1 Positive Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
AIM18 YHR198C Protein of unknown function genetic 1 1 1 Positive Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Phenotypic Suppression
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Dosage Lethality
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
RSM19 YNR037C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
TUL1 YKL034W Subunit of the DSC ubiquitin ligase complex genetic 1 1 1 Positive Genetic
SML1 YML058W Ribonucleotide reductase inhibitor genetic 1 1 1 Phenotypic Enhancement
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 1 1 1 Negative Genetic
MNT4 YNR059W Putative alpha-1,3-mannosyltransferase genetic 1 1 1 Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Negative Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
COQ10 YOL008W Coenzyme Q (ubiquinone) binding protein genetic 1 1 1 Negative Genetic
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
ARO3 YDR035W 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase physical 1 1 1 Affinity Capture-MS
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Positive Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
CTH1 YDR151C mRNA binding protein, member of the CCCH zinc finger family physical 1 1 1 Two-hybrid
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
NEJ1 YLR265C DNA end-binding protein required for nonhomologous end joining (NHEJ) genetic 1 1 1 Negative Genetic
RPS18B YML026C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
COQ2 YNR041C Para hydroxybenzoate polyprenyl transferase genetic 1 1 1 Negative Genetic
MET8 YBR213W Bifunctional dehydrogenase and ferrochelatase genetic 1 1 1 Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Negative Genetic
CUR1 YPR158W Sorting factor, central regulator of spatial protein quality control genetic 1 1 1 Negative Genetic
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
PUN1 YLR414C Plasma membrane protein with a role in cell wall integrity genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
EFM5 YGR001C S-adenosylmethionine-dependent lysine methyltransferase genetic 1 1 1 Negative Genetic
FLX1 YIL134W Mitochondrial flavin adenine dinucleotide transporter genetic 1 1 1 Negative Genetic
TIS11 YLR136C mRNA-binding protein expressed during iron starvation physical 1 1 1 Two-hybrid
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Positive Genetic
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic