| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TOP1 |
YOL006C |
Topoisomerase I |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| GSH1 |
YJL101C |
Gamma glutamylcysteine synthetase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RPI1 |
YIL119C |
Transcription factor, allelic differences between S288C and Sigma1278b |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| SAK1 |
YER129W |
Upstream serine/threonine kinase for the SNF1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CSR2 |
YPR030W |
Nuclear ubiquitin protein ligase binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FUB1 |
YCR076C |
Proteasome-binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LCL1 |
YPL056C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MPC1 |
YGL080W |
Highly conserved subunit of mitochondrial pyruvate carrier (MPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YDR042C |
YDR042C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YDR248C |
YDR248C |
Putative gluconokinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| POP4 |
YBR257W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL24 |
YMR193W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR7 |
YFR008W |
Protein involved in recovery from pheromone-induced cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PPE1 |
YHR075C |
Protein with carboxyl methyl esterase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR3 |
YMR052W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IKS1 |
YJL057C |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| PEA2 |
YER149C |
Coiled-coil 12S polarisome subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBH1 |
YER087C-B |
Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) |
physical |
1 |
1 |
1 |
Two-hybrid |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SIP4 |
YJL089W |
C6 zinc cluster transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHT2 |
YNL031C |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUB1 |
YNR032C-A |
Ubiquitin-like protein modifier |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPM2 |
YIL138C |
Minor isoform of tropomyosin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HMG1 |
YML075C |
HMG-CoA reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IAI11 |
YBL059W |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGR1 |
YCL044C |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIR4 |
YOR009W |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSS18 |
YPR134W |
Nuclear encoded protein needed for splicing of mitochondrial intron |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KTR6 |
YPL053C |
Probable mannosylphosphate transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR029C |
YNR029C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YKR018C |
YKR018C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ZNF1 |
YFL052W |
Zinc cluster transcription factor that regulates respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR242W-A |
YMR242W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISR1 |
YPR106W |
Predicted protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAD4 |
YDL243C |
Putative aryl-alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX13 |
YGL191W |
Subunit VIa of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TVS1 |
YCR061W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IML2 |
YJL082W |
Protein required for clearance of inclusion bodies |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB4 |
YOR171C |
Sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PFA5 |
YDR459C |
Palmitoyltransferase with autoacylation activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS2 |
YDL107W |
Peripherally bound inner membrane protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMP30 |
YPL103C |
Protein with a role in maintaining mitochondrial morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NFT1 |
YKR103W |
Putative transporter of the MRP subfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCF2 |
YNR018W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRX11 |
YPL041C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Negative Genetic |
| WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR122W |
YGR122W |
Protein that may be involved in pH regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER187W |
YER187W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAU9 |
YBL108C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
