Standard name Systematic name Name description Description
YVH1 YIR026C Dual specificity protein phosphatase Dual specificity protein phosphatase; regulates growth, sporulation, and glycogen accumulation in a cAMP-dependent protein kinase cascade dependent manner; mutants are defective in 60S ribosome assembly; positively regulates pre-autophagosomal structure (PAS) formation upon nitrogen starvation or rapamycin treatment
Visualize the interactome of YVH1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.984 0.987 0.969

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 7570

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
YVH1 1 4 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
LSG1 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis physical 9 4 8 Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 7 2 6 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit physical 7 2 6 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 4 3 3 Synthetic Rescue, Dosage Lethality, Synthetic Rescue, Dosage Rescue
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export physical 3 2 2 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western
REI1 YBR267W Cytoplasmic pre-60S factor physical 2 2 2 PCA, Affinity Capture-Western
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 2 2 2 PCA, Affinity Capture-Western
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 2 2 2 Phenotypic Suppression, Synthetic Rescue
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 2 1 2 Negative Genetic, Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 1 2 Negative Genetic, Negative Genetic
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 2 2 1 Affinity Capture-Western, Co-fractionation
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Positive Genetic
ERB1 YMR049C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
NOP7 YGR103W Component of several different pre-ribosomal particles physical 1 1 1 Two-hybrid
NOP7 YGR103W Component of several different pre-ribosomal particles genetic 1 1 1 Dosage Rescue
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
CIC1 YHR052W Essential protein that interacts with proteasome components physical 1 1 1 Affinity Capture-MS
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs physical 1 1 1 Affinity Capture-MS
ALB1 YJL122W Shuttling pre-60S factor physical 1 1 1 Affinity Capture-Western
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit physical 1 1 1 Affinity Capture-MS
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Dosage Rescue
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit genetic 1 1 1 Synthetic Growth Defect
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Lethality
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
MKT1 YNL085W Protein similar to nucleases that forms a complex with Pbp1p genetic 1 1 1 Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Dosage Rescue
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Dosage Rescue
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Positive Genetic
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
HEL2 YDR266C RING finger ubiquitin ligase (E3) genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Negative Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase genetic 1 1 1 Negative Genetic
DIP5 YPL265W Dicarboxylic amino acid permease physical 1 1 1 PCA
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Positive Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-Western
PTP2 YOR208W Phosphotyrosine-specific phosphatase genetic 1 1 1 Phenotypic Enhancement
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Dosage Rescue
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 1 1 1 Negative Genetic
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Negative Genetic
PML1 YLR016C Subunit of the RES complex genetic 1 1 1 Negative Genetic
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 1 1 1 Affinity Capture-Western
APL4 YPR029C Gamma-adaptin physical 1 1 1 Affinity Capture-MS
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Positive Genetic
SKA1 YKL023W SKI complex-associated protein physical 1 1 1 Affinity Capture-MS
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Dosage Rescue
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
IME1 YJR094C Master regulator of meiosis that is active only during meiotic events genetic 1 1 1 Dosage Rescue
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Positive Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis physical 1 1 1 Co-purification
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Positive Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
MTR2 YKL186C mRNA transport regulator physical 1 1 1 Reconstituted Complex
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 1 1 1 Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
SFK1 YKL051W Protein that regulates phospholipid asymmetry at plasma membrane physical 1 1 1 PCA
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Positive Genetic
PEX11 YOL147C Peroxisomal protein required for medium-chain fatty acid oxidation physical 1 1 1 PCA
GTT1 YIR038C ER associated glutathione S-transferase physical 1 1 1 PCA
HUB1 YNR032C-A Ubiquitin-like protein modifier genetic 1 1 1 Negative Genetic
PDR12 YPL058C Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine physical 1 1 1 PCA
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 1 1 1 Dosage Lethality
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
SOK1 YDR006C Protein of unknown function genetic 1 1 1 Negative Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
CAB4 YGR277C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
ALD2 YMR170C Cytoplasmic aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
RPL12A YEL054C Ribosomal 60S subunit protein L12A physical 1 1 1 Affinity Capture-Western
OGG1 YML060W Nuclear and mitochondrial glycosylase/lyase genetic 1 1 1 Negative Genetic
RPL24A YGL031C Ribosomal 60S subunit protein L24A physical 1 1 1 Affinity Capture-Western
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Positive Genetic
HXT1 YHR094C Low-affinity glucose transporter of the major facilitator superfamily physical 1 1 1 PCA
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Synthetic Growth Defect
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Positive Genetic
CRT10 YOL063C Protein required for the degradation of mutant 25S rRNAs physical 1 1 1 Affinity Capture-MS
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Negative Genetic
RPL12B YDR418W Ribosomal 60S subunit protein L12B physical 1 1 1 Affinity Capture-Western
RPL12B YDR418W Ribosomal 60S subunit protein L12B genetic 1 1 1 Dosage Rescue
TAX4 YJL083W EH domain-containing protein physical 1 1 1 Affinity Capture-MS
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase genetic 1 1 1 Negative Genetic
SFG1 YOR315W Nuclear protein putative transcription factor genetic 1 1 1 Negative Genetic
YOL036W YOL036W Protein of unknown function genetic 1 1 1 Negative Genetic
VTC5 YDR089W Novel subunit of the vacuolar transporter chaperone complex genetic 1 1 1 Negative Genetic