Standard name Systematic name Name description Description
AFT2 YPL202C Iron-regulated transcriptional activator Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; AFT2 has a paralog, AFT1, that arose from the whole genome duplication
Visualize the interactome of AFT2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
ambiguous technical problem

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
AFT2 4 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis genetic 11 5 9 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Dosage Rescue, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect
DIT2 YDR402C N-formyltyrosine oxidase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FAA1 YOR317W Long chain fatty acyl-CoA synthetase regulation 2 2 2 beta-galactosidase reporter gene assay evidence, chromatin immunoprecipitation-chip evidence
AFT2 YPL202C Iron-regulated transcriptional activator physical 2 1 2 Reconstituted Complex, Reconstituted Complex
GRX3 YDR098C Glutathione-dependent oxidoreductase physical 2 1 2 Reconstituted Complex, Reconstituted Complex
BOL2 YGL220W Cytosolic protein involved in repression of iron regulon transcription physical 2 1 2 Reconstituted Complex, Reconstituted Complex
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 2 1 2 Negative Genetic, Negative Genetic
MSH4 YFL003C Protein involved in meiotic recombination genetic 2 1 2 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
BMH1 YER177W 14-3-3 protein, major isoform regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TMC1 YOR052C AN1-type zinc finger protein, effector of proteotoxic stress response regulation 1 1 1 DNA to cDNA expression microarray evidence
ALP1 YNL270C Arginine transporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YPS1 YLR120C Aspartic protease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CLB2 YPR119W B-type cyclin involved in cell cycle progression regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CMK2 YOL016C Calmodulin-dependent protein kinase regulation 1 1 1 DNA to cDNA expression microarray evidence
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YGR130C YGR130C Component of the eisosome with unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ISU1 YPL135W Conserved protein of the mitochondrial matrix regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CCC2 YDR270W Cu(+2)-transporting P-type ATPase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p regulation 1 1 1 DNA to cDNA expression microarray evidence
GIP3 YPL137C Cytoplasmic protein that regulates protein phosphatase 1 Glc7p regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ATX1 YNL259C Cytosolic copper metallochaperone regulation 1 1 1 chromatin immunoprecipitation-chip evidence
OLE1 YGL055W Delta(9) fatty acid desaturase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSP104 YLL026W Disaggregase regulation 1 1 1 DNA to cDNA expression microarray evidence
YDL023C YDL023C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HMX1 YLR205C ER localized heme oxygenase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GLK1 YCL040W Glucokinase regulation 1 1 1 DNA to cDNA expression microarray evidence
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NCW2 YLR194C GPI-anchored protein involved in cell wall remodeling regulation 1 1 1 DNA to cDNA expression microarray evidence
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FTR1 YER145C High affinity iron permease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GIR2 YDR152W Highly-acidic RWD domain-containing cytoplasmic protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TYC1 YBR296C-A Inhibitor of the Anaphase-Promoting Complex/Cyclosome (APC/C) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YNL194C YNL194C Integral membrane protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MRS4 YKR052C Iron transporter of the mitochondrial carrier family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LSM5 YER146W Lsm (Like Sm) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LYP1 YNL268W Lysine permease regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MAL33 YBR297W MAL-activator protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPO19 YPL130W Meiosis-specific prospore protein regulation 1 1 1 DNA to cDNA expression microarray evidence
RSN1 YMR266W Membrane protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ISU2 YOR226C Mitochondrial protein required for iron-sulfur protein synthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CTH1 YDR151C mRNA binding protein, member of the CCCH zinc finger family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FET5 YFL041W Multicopper oxidase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RCH1 YMR034C Negative regulator of cytosolic calcium homeostasis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSL1 YKL101W Nim1p-related protein kinase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RHO2 YNL090W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO89 YBR296C Plasma membrane Na+/Pi cotransporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RCR1 YBR005W Plasma membrane (PM) ubiquitin ligase-substrate adaptor regulation 1 1 1 DNA to cDNA expression microarray evidence
AGP2 YBR132C Plasma membrane regulator of polyamine and carnitine transport regulation 1 1 1 chromatin immunoprecipitation-chip evidence
APT2 YDR441C Potential adenine phosphoribosyltransferase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SDS23 YGL056C Protein involved in cell separation during budding regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSH5 YDL154W Protein of the MutS family regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RCN2 YOR220W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
FHN1 YGR131W Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
DIA1 YMR316W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR162W YLR162W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
JIP4 YDR475C Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HER1 YOR227W Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YMR316C-A YMR316C-A Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
AIM17 YHL021C Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
SUE1 YPR151C Protein required for degradation of unstable forms of cytochrome c regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MND1 YGL183C Protein required for recombination and meiotic nuclear division regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LSO1 YJR005C-A Protein with a potential role in response to iron deprivation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ATR2 YMR279C Putative boron transporter involved in boron efflux and resistance regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SMF3 YLR034C Putative divalent metal ion transporter involved in iron homeostasis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FTH1 YBR207W Putative high affinity iron transporter regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MMT1 YMR177W Putative metal transporter involved in mitochondrial iron accumulation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation regulation 1 1 1 beta-galactosidase reporter gene assay evidence
YMR265C YMR265C Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YNL193W YNL193W Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YOR385W YOR385W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YOR316C-A YOR316C-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YFL041W-A YFL041W-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RRT15 YLR162W-A Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YOL014W YOL014W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YMR085W YMR085W Putative protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YPL034W YPL034W Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LAM5 YFL042C Putative sterol transfer protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
LTO1 YNL260C Substrate-specific adaptor protein involved in apo-Rli1p maturation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SLM4 YBR077C Subunit of the EGO/GSE complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
APE1 YKL103C Vacuolar aminopeptidase yscI regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PRB1 YEL060C Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COT1 YOR316C Vacuolar transporter that mediates zinc transport into the vacuole regulation 1 1 1 chromatin immunoprecipitation-chip evidence
BTN2 YGR142W v-SNARE binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SKN7 YHR206W Nuclear response regulator and transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Lethality
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Negative Genetic
XDJ1 YLR090W Chaperone with a role in facilitating mitochondrial protein import genetic 1 1 1 Negative Genetic
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Synthetic Growth Defect
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Synthetic Growth Defect
MIT1 YEL007W Transcriptional regulator of pseudohyphal growth genetic 1 1 1 Synthetic Growth Defect
ZAP1 YJL056C Zinc-regulated transcription factor genetic 1 1 1 Negative Genetic
MET32 YDR253C Zinc-finger DNA-binding transcription factor genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
CIN2 YPL241C GTPase-activating protein (GAP) for Cin4p genetic 1 1 1 Negative Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Positive Genetic
PLM2 YDR501W Putative transcription factor, contains Forkhead Associated domain genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Negative Genetic
DRE2 YKR071C Component of the cytosolic Fe-S protein assembly (CIA) machinery genetic 1 1 1 Phenotypic Suppression
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
MRPL27 YBR282W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 1 1 1 Negative Genetic
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
YEF1 YEL041W ATP-NADH kinase genetic 1 1 1 Negative Genetic
YHR050W-A YHR050W-A Protein of unknown function genetic 1 1 1 Negative Genetic
OYE2 YHR179W Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) genetic 1 1 1 Negative Genetic
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Negative Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Dosage Lethality
PUT1 YLR142W Proline oxidase genetic 1 1 1 Negative Genetic
COQ9 YLR201C Protein required for ubiquinone biosynthesis and respiratory growth genetic 1 1 1 Negative Genetic
AMD1 YML035C AMP deaminase genetic 1 1 1 Negative Genetic
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
IME4 YGL192W mRNA N6-adenosine methyltransferase genetic 1 1 1 Phenotypic Enhancement
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase genetic 1 1 1 Phenotypic Enhancement
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Negative Genetic
GAC1 YOR178C Regulatory subunit for Glc7p type-1 protein phosphatase (PP1) genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 1 1 1 Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
TMA23 YMR269W Nucleolar protein implicated in ribosome biogenesis genetic 1 1 1 Negative Genetic
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect