| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
| STP1 |
YDR463W |
Transcription factor |
regulation |
2 |
1 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| DIP5 |
YPL265W |
Dicarboxylic amino acid permease |
physical |
2 |
1 |
2 |
PCA, PCA |
| RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS33 |
YLR396C |
ATP-binding protein that is a subunit of the HOPS and CORVET complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| NPR1 |
YNL183C |
Protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BNI1 |
YNL271C |
Formin |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| PHD1 |
YKL043W |
Transcriptional activator that enhances pseudohyphal growth |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACO1 |
YLR304C |
Aconitase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAT2 |
YLR027C |
Cytosolic aspartate aminotransferase involved in nitrogen metabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UTP13 |
YLR222C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SHR3 |
YDL212W |
Endoplasmic reticulum packaging chaperone |
physical |
1 |
1 |
1 |
PCA |
| SNQ2 |
YDR011W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
PCA |
| PLM2 |
YDR501W |
Putative transcription factor, contains Forkhead Associated domain |
physical |
1 |
1 |
1 |
PCA |
| SDS23 |
YGL056C |
Protein involved in cell separation during budding |
physical |
1 |
1 |
1 |
PCA |
| HNM1 |
YGL077C |
Plasma membrane transporter for choline, ethanolamine, and carnitine |
physical |
1 |
1 |
1 |
PCA |
| MUP1 |
YGR055W |
High affinity methionine permease |
physical |
1 |
1 |
1 |
PCA |
| HXT1 |
YHR094C |
Low-affinity glucose transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
PCA |
| HXT5 |
YHR096C |
Hexose transporter with moderate affinity for glucose |
physical |
1 |
1 |
1 |
PCA |
| YVH1 |
YIR026C |
Dual specificity protein phosphatase |
physical |
1 |
1 |
1 |
PCA |
| TPO1 |
YLL028W |
Polyamine transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
PCA |
| TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
physical |
1 |
1 |
1 |
PCA |
| SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
physical |
1 |
1 |
1 |
PCA |
| LYP1 |
YNL268W |
Lysine permease |
physical |
1 |
1 |
1 |
PCA |
| PDR5 |
YOR153W |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
PCA |
| PDR12 |
YPL058C |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
PCA |
| WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
physical |
1 |
1 |
1 |
Protein-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GIT1 |
YCR098C |
Plasma membrane permease |
physical |
1 |
1 |
1 |
PCA |
| YHL042W |
YHL042W |
Endoplasmic reticulum protein |
physical |
1 |
1 |
1 |
PCA |
| NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| GNP1 |
YDR508C |
Broad specificity amino acid permease |
physical |
1 |
1 |
1 |
PCA |
| MEP1 |
YGR121C |
Ammonium permease |
physical |
1 |
1 |
1 |
PCA |
| MEP2 |
YNL142W |
Ammonium permease involved in regulation of pseudohyphal growth |
physical |
1 |
1 |
1 |
PCA |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MMF1 |
YIL051C |
Mitochondrial protein required for transamination of isoleucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSY1 |
YDR160W |
Component of the SPS plasma membrane amino acid sensor system |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| GAP1 |
YKR039W |
General amino acid permease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB4 |
YOR171C |
Sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAA1 |
YLR088W |
Subunit of the GPI:protein transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GNA1 |
YFL017C |
Glucosamine-6-phosphate acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI12 |
YMR281W |
ER membrane protein involved in the second step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL19 |
YNL185C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGM1 |
YOR211C |
Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACO2 |
YJL200C |
Putative mitochondrial aconitase isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALY2 |
YJL084C |
Alpha arrestin, Ub-ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AST2 |
YER101C |
Lipid raft associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ4 |
YDR204W |
Protein with a role in ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BAP2 |
YBR068C |
High-affinity leucine permease |
physical |
1 |
1 |
1 |
PCA |
| AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
physical |
1 |
1 |
1 |
PCA |