Standard name Systematic name Name description Description
RED1 YLR263W Protein component of the synaptonemal complex axial elements Protein component of the synaptonemal complex axial elements; involved in chromosome segregation during the first meiotic division; critical for coupling checkpoint signaling to SC formation; promotes interhomolog recombination by phosphorylating Hop1p; also interacts with Mec3p and Ddc1p
Visualize the interactome of RED1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.979 0.984 0.988

GFP localization & abundance

GFP localization GFP abundance
cytoplasm no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RED1 0 1 0 1 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
HOP1 YIL072W Meiosis-specific protein required for chromosome synapsis physical 9 5 7 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Far Western, Reconstituted Complex, Protein-peptide
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase physical 6 3 2 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Biochemical Activity
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 5 4 3 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Two-hybrid, Biochemical Activity
DMC1 YER179W Meiosis-specific recombinase required for double-strand break repair genetic 3 3 3 Synthetic Rescue, Synthetic Lethality, Phenotypic Suppression
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex genetic 3 3 3 Dosage Rescue, Phenotypic Enhancement, Synthetic Rescue
RED1 YLR263W Protein component of the synaptonemal complex axial elements physical 3 2 3 Two-hybrid, Two-hybrid, Reconstituted Complex
HOP1 YIL072W Meiosis-specific protein required for chromosome synapsis genetic 3 2 3 Dosage Rescue, Dosage Rescue, Phenotypic Suppression
SPO22 YIL073C Meiosis-specific protein essential for chromosome synapsis physical 3 3 1 Affinity Capture-MS, Affinity Capture-Western, Two-hybrid
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 2 2 2 Dosage Lethality, Dosage Rescue
DDC1 YPL194W DNA damage checkpoint protein physical 2 1 2 Two-hybrid, Two-hybrid
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 2 1 2 Two-hybrid, Two-hybrid
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 2 1 2 Negative Genetic, Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Dosage Growth Defect
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Dosage Growth Defect
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
RAD51 YER095W Strand exchange protein genetic 1 1 1 Synthetic Rescue
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Dosage Rescue
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Positive Genetic
PDS1 YDR113C Securin genetic 1 1 1 Phenotypic Suppression
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Synthetic Rescue
LSC1 YOR142W Alpha subunit of succinyl-CoA ligase genetic 1 1 1 Negative Genetic
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p physical 1 1 1 Two-hybrid
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein physical 1 1 1 Two-hybrid
MDH3 YDL078C Peroxisomal malate dehydrogenase genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Synthetic Lethality
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors physical 1 1 1 Affinity Capture-MS
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients physical 1 1 1 Biochemical Activity
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex physical 1 1 1 Two-hybrid
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway physical 1 1 1 Two-hybrid
ZIP2 YGL249W Meiosis-specific protein physical 1 1 1 Affinity Capture-MS
ZIP2 YGL249W Meiosis-specific protein genetic 1 1 1 Dosage Rescue
SPO16 YHR153C Meiosis-specific protein involved in synaptonemal complex assembly physical 1 1 1 Affinity Capture-MS
SPO13 YHR014W Meiotic regulator genetic 1 1 1 Synthetic Rescue
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Synthetic Rescue
SAE2 YGL175C Endonuclease required for telomere elongation genetic 1 1 1 Phenotypic Suppression
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Dosage Growth Defect
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Positive Genetic
RSM27 YGR215W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 1 1 1 Phenotypic Suppression
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Positive Genetic
HOP2 YGL033W Meiosis-specific protein that localizes to chromosomes genetic 1 1 1 Dosage Rescue
REC102 YLR329W Protein involved in early stages of meiotic recombination genetic 1 1 1 Negative Genetic
ATC1 YDR184C Nuclear protein genetic 1 1 1 Negative Genetic
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Dosage Growth Defect
REC8 YPR007C Meiosis-specific component of the sister chromatid cohesion complex physical 1 1 1 Affinity Capture-Western
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
HED1 YDR014W-A Meiosis-specific protein genetic 1 1 1 Dosage Rescue
PCH2 YBR186W Hexameric ring ATPase that remodels chromosome axis protein Hop1p genetic 1 1 1 Phenotypic Suppression
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
CSM4 YPL200W Protein required for accurate chromosome segregation during meiosis genetic 1 1 1 Phenotypic Suppression
ALK2 YBL009W Atypical protein kinase genetic 1 1 1 Negative Genetic
MND1 YGL183C Protein required for recombination and meiotic nuclear division genetic 1 1 1 Phenotypic Suppression