| SRB4 |
YER022W |
Subunit of the RNA polymerase II mediator complex |
physical |
21 |
5 |
18 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Co-purification, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
physical |
10 |
5 |
6 |
Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Co-crystal Structure, Affinity Capture-Western, Reconstituted Complex |
| SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
physical |
8 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
| MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
physical |
7 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western |
| GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, PCA |
| CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SRB7 |
YDR308C |
Subunit of the RNA polymerase II mediator complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| SRB4 |
YER022W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| ADA2 |
YDR448W |
Transcription coactivator |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC40 |
YDR364C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP49 |
YKL167C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL39 |
YML009C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAM33 |
YIL070C |
Acidic protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL38 |
YKL170W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROX3 |
YBL093C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE1 |
YGL238W |
Nuclear envelope protein that acts as a recycling factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
PCA |
| SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SUA7 |
YPR086W |
Transcription factor TFIIB |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
physical |
1 |
1 |
1 |
Co-localization |
| TFB4 |
YPR056W |
Subunit of TFIIH complex |
physical |
1 |
1 |
1 |
Co-purification |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRL3 |
YKR091W |
Repressor of transcription at Start |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR407W |
YLR407W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL131W |
YOL131W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRM44 |
YPL030W |
tRNA(Ser) Um(44) 2'-O-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUN4 |
YNL066W |
Cell wall protein related to glucanases localized in birth scars |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MKS1 |
YNL076W |
Pleiotropic negative transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APP1 |
YNL094W |
Phosphatidate phosphatase, converts phosphatidate to diacylglycerol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNQ1 |
YCL028W |
[PIN(+)] prion |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PRM2 |
YIL037C |
Pheromone-regulated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHT1 |
YBR010W |
Histone H3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OMS1 |
YDR316W |
Protein integral to the mitochondrial membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUT1 |
YBR252W |
Deoxyuridine triphosphate diphosphatase (dUTPase) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSG5 |
YNL053W |
Dual-specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RNR3 |
YIL066C |
Minor isoform of large subunit of ribonucleotide-diphosphate reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAK1 |
YFL029C |
Cyclin-dependent kinase-activating kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTL1 |
YCR020W-B |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PAM18 |
YLR008C |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAL4 |
YPL248C |
DNA-binding transcription factor required for activating GAL genes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIC1 |
YHR061C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET122 |
YER153C |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APN2 |
YBL019W |
Class II abasic (AP) endonuclease involved in repair of DNA damage |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EUC1 |
YMR111C |
Sequence-specific DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIT1 |
YEL007W |
Transcriptional regulator of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPB1 |
YOR371C |
Multistep regulator of cAMP-PKA signaling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MTG1 |
YMR097C |
Putative GTPase peripheral to the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS14B |
YJL191W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CYC2 |
YOR037W |
Mitochondrial peripheral inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFG16 |
YOR030W |
Probable multiple transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCF2 |
YNR018W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSC6 |
YOR354C |
Multicopy suppressor of HER2 involved in mitochondrial translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNE1 |
YOR350C |
Protein involved in splicing Group I aI5-beta intron from COX1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FYV12 |
YOR183W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIN3 |
YMR182W-A |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
