| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
physical |
11 |
5 |
6 |
Affinity Capture-Western, Co-localization, Co-localization, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-MS |
| ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
physical |
7 |
4 |
2 |
Co-localization, Co-localization, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
| VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| AVT5 |
YBL089W |
Putative transporter |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| DOT1 |
YDR440W |
Nucleosomal histone H3-Lys79 methylase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG14 |
YBR128C |
Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG18 |
YFR021W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG20 |
YDL113C |
Sorting nexin family member |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG13 |
YPR185W |
Regulatory subunit of the Atg1p signaling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NDL1 |
YLR254C |
Homolog of nuclear distribution factor NudE |
physical |
1 |
1 |
1 |
Two-hybrid |
| CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DNF2 |
YDR093W |
Aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RHO1 |
YPR165W |
GTP-binding protein of the rho subfamily of Ras-like proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SAR1 |
YPL218W |
ARF family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSO2 |
YMR183C |
Plasma membrane t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS45 |
YGL095C |
Protein of the Sec1p/Munc-18 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DNF1 |
YER166W |
Aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SDS24 |
YBR214W |
Protein involved in cell separation during budding |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YOP1 |
YPR028W |
Reticulon-interacting protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT52 |
YKR014C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EMP46 |
YLR080W |
Integral membrane component of ER-derived COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RBD2 |
YPL246C |
Possible rhomboid protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC22 |
YLR268W |
R-SNARE protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YIP1 |
YGR172C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EMP24 |
YGL200C |
Component of the p24 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFT1 |
YKL006C-A |
Intra-Golgi v-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC21 |
YNL287W |
Gamma subunit of coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TVP38 |
YKR088C |
Integral membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PEP12 |
YOR036W |
Target membrane receptor (t-SNARE) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT31 |
YER031C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT7 |
YML001W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YIP3 |
YNL044W |
Protein localized to COPII vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| EMP47 |
YFL048C |
Integral membrane component of ER-derived COPII-coated vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSP120 |
YLR250W |
Protein packaged into COPII vesicles for ER to Golgi trafficking |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| YPT1 |
YFL038C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SFT2 |
YBL102W |
Tetra-spanning membrane protein found mostly in the late Golgi |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SSO1 |
YPL232W |
Plasma membrane t-SNARE |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG23 |
YLR431C |
Peripheral membrane protein required for autophagy and CVT |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL092W |
YNL092W |
S-adenosylmethionine-dependent protein methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG29 |
YPL166W |
Autophagy-specific protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG3 |
YNR007C |
E2-like enzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG32 |
YIL146C |
Mitochondrial outer membrane protein required to initiate mitophagy |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG4 |
YNL223W |
Conserved cysteine protease required for autophagy |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG5 |
YPL149W |
Conserved protein involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG7 |
YHR171W |
Autophagy-related protein and dual specificity member of the E1 family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CLG1 |
YGL215W |
Cyclin-like protein that interacts with Pho85p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP1 |
YER047C |
Putative ATPase of the AAA family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX4 |
YGL187C |
Subunit IV of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZRT1 |
YGL255W |
High-affinity zinc transporter of the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOT13 |
YKL084W |
Zinc-binding mitochondrial intermembrane space (IMS) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSM22 |
YKL155C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRP49 |
YKL167C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIF1 |
YML061C |
DNA helicase, potent G-quadruplex DNA binder/unwinder |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL22 |
YNL177C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISM1 |
YPL040C |
Mitochondrial isoleucyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATG10 |
YLL042C |
Conserved E2-like conjugating enzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATG15 |
YCR068W |
Phospholipase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| AAD16 |
YFL057C |
Putative aryl alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |